PMC:7534795 / 85058-85335 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T406","span":{"begin":30,"end":35},"obj":"Body_part"},{"id":"T407","span":{"begin":65,"end":68},"obj":"Body_part"},{"id":"T408","span":{"begin":118,"end":125},"obj":"Body_part"}],"attributes":[{"id":"A406","pred":"fma_id","subj":"T406","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A407","pred":"fma_id","subj":"T407","obj":"http://purl.org/sig/ont/fma/fma82785"},{"id":"A408","pred":"fma_id","subj":"T408","obj":"http://purl.org/sig/ont/fma/fma74413"}],"text":"In a study using HL-1 cardiac cells, 19,20-EDP protected against LPS-stimulated inflammatory injury by activating the histone deacetylase Sirtuin-1 inhibiting the activation the pro-inflammatory transcription factor NF-κB (Samokhvalov, Jamieson, Vriend, Quan, \u0026 Seubert, 2015)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T493","span":{"begin":93,"end":99},"obj":"Disease"}],"attributes":[{"id":"A493","pred":"mondo_id","subj":"T493","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"}],"text":"In a study using HL-1 cardiac cells, 19,20-EDP protected against LPS-stimulated inflammatory injury by activating the histone deacetylase Sirtuin-1 inhibiting the activation the pro-inflammatory transcription factor NF-κB (Samokhvalov, Jamieson, Vriend, Quan, \u0026 Seubert, 2015)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T561","span":{"begin":3,"end":4},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T562","span":{"begin":17,"end":21},"obj":"http://purl.obolibrary.org/obo/CLO_0052763"},{"id":"T563","span":{"begin":30,"end":35},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T564","span":{"begin":103,"end":113},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T565","span":{"begin":163,"end":173},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T566","span":{"begin":220,"end":221},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"}],"text":"In a study using HL-1 cardiac cells, 19,20-EDP protected against LPS-stimulated inflammatory injury by activating the histone deacetylase Sirtuin-1 inhibiting the activation the pro-inflammatory transcription factor NF-κB (Samokhvalov, Jamieson, Vriend, Quan, \u0026 Seubert, 2015)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T651","span":{"begin":17,"end":19},"obj":"Chemical"},{"id":"T652","span":{"begin":37,"end":46},"obj":"Chemical"},{"id":"T653","span":{"begin":65,"end":68},"obj":"Chemical"},{"id":"T656","span":{"begin":118,"end":125},"obj":"Chemical"},{"id":"T657","span":{"begin":216,"end":218},"obj":"Chemical"}],"attributes":[{"id":"A651","pred":"chebi_id","subj":"T651","obj":"http://purl.obolibrary.org/obo/CHEBI_5729"},{"id":"A652","pred":"chebi_id","subj":"T652","obj":"http://purl.obolibrary.org/obo/CHEBI_72653"},{"id":"A653","pred":"chebi_id","subj":"T653","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"id":"A654","pred":"chebi_id","subj":"T653","obj":"http://purl.obolibrary.org/obo/CHEBI_52603"},{"id":"A655","pred":"chebi_id","subj":"T653","obj":"http://purl.obolibrary.org/obo/CHEBI_89981"},{"id":"A656","pred":"chebi_id","subj":"T656","obj":"http://purl.obolibrary.org/obo/CHEBI_15358"},{"id":"A657","pred":"chebi_id","subj":"T657","obj":"http://purl.obolibrary.org/obo/CHEBI_141424"},{"id":"A658","pred":"chebi_id","subj":"T657","obj":"http://purl.obolibrary.org/obo/CHEBI_25573"},{"id":"A659","pred":"chebi_id","subj":"T657","obj":"http://purl.obolibrary.org/obo/CHEBI_1224"}],"text":"In a study using HL-1 cardiac cells, 19,20-EDP protected against LPS-stimulated inflammatory injury by activating the histone deacetylase Sirtuin-1 inhibiting the activation the pro-inflammatory transcription factor NF-κB (Samokhvalov, Jamieson, Vriend, Quan, \u0026 Seubert, 2015)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T195","span":{"begin":195,"end":215},"obj":"http://purl.obolibrary.org/obo/GO_0000981"},{"id":"T196","span":{"begin":195,"end":208},"obj":"http://purl.obolibrary.org/obo/GO_0006351"}],"text":"In a study using HL-1 cardiac cells, 19,20-EDP protected against LPS-stimulated inflammatory injury by activating the histone deacetylase Sirtuin-1 inhibiting the activation the pro-inflammatory transcription factor NF-κB (Samokhvalov, Jamieson, Vriend, Quan, \u0026 Seubert, 2015)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T564","span":{"begin":0,"end":277},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In a study using HL-1 cardiac cells, 19,20-EDP protected against LPS-stimulated inflammatory injury by activating the histone deacetylase Sirtuin-1 inhibiting the activation the pro-inflammatory transcription factor NF-κB (Samokhvalov, Jamieson, Vriend, Quan, \u0026 Seubert, 2015)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2392","span":{"begin":138,"end":147},"obj":"Gene"},{"id":"2393","span":{"begin":216,"end":221},"obj":"Gene"},{"id":"2425","span":{"begin":39,"end":46},"obj":"Chemical"},{"id":"2426","span":{"begin":65,"end":68},"obj":"Chemical"},{"id":"2438","span":{"begin":80,"end":99},"obj":"Disease"},{"id":"2443","span":{"begin":17,"end":21},"obj":"CellLine"}],"attributes":[{"id":"A2392","pred":"tao:has_database_id","subj":"2392","obj":"Gene:23411"},{"id":"A2393","pred":"tao:has_database_id","subj":"2393","obj":"Gene:4790"},{"id":"A2426","pred":"tao:has_database_id","subj":"2426","obj":"MESH:D008070"},{"id":"A2438","pred":"tao:has_database_id","subj":"2438","obj":"MESH:D007249"},{"id":"A2443","pred":"tao:has_database_id","subj":"2443","obj":"CVCL:0303"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In a study using HL-1 cardiac cells, 19,20-EDP protected against LPS-stimulated inflammatory injury by activating the histone deacetylase Sirtuin-1 inhibiting the activation the pro-inflammatory transcription factor NF-κB (Samokhvalov, Jamieson, Vriend, Quan, \u0026 Seubert, 2015)."}