PMC:7534795 / 65014-65451 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T263","span":{"begin":256,"end":265},"obj":"Body_part"}],"attributes":[{"id":"A263","pred":"fma_id","subj":"T263","obj":"http://purl.org/sig/ont/fma/fma241981"}],"text":". (D) N-3 PUFAs, DHA and EPA, are metabolized by CYP epoxygenases into bioactive epoxylipids with anti-inflammatory properties. (E) N-3 PUFAs are metabolized by COX/LOX into SPMs which act as potent anti-inflammatory modulators. AA, Arachidonic acid; CCL, Chemokine ligand; COX, Cyclooxygenase; CYP, Cytochrome P450; DHA, Docosahexaenoic acid; EDP, Epoxydocosapentaenoic acid; EEQ, Epoxyeicosatetraenoic acid; EPA, Eicosapentaenoic acid;"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T393","span":{"begin":128,"end":133},"obj":"http://purl.obolibrary.org/obo/CLO_0037161"},{"id":"T394","span":{"begin":229,"end":231},"obj":"http://purl.obolibrary.org/obo/CLO_0001627"}],"text":". (D) N-3 PUFAs, DHA and EPA, are metabolized by CYP epoxygenases into bioactive epoxylipids with anti-inflammatory properties. (E) N-3 PUFAs are metabolized by COX/LOX into SPMs which act as potent anti-inflammatory modulators. AA, Arachidonic acid; CCL, Chemokine ligand; COX, Cyclooxygenase; CYP, Cytochrome P450; DHA, Docosahexaenoic acid; EDP, Epoxydocosapentaenoic acid; EEQ, Epoxyeicosatetraenoic acid; EPA, Eicosapentaenoic acid;"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T41515","span":{"begin":10,"end":15},"obj":"Chemical"},{"id":"T49437","span":{"begin":17,"end":20},"obj":"Chemical"},{"id":"T8273","span":{"begin":25,"end":28},"obj":"Chemical"},{"id":"T273","span":{"begin":49,"end":52},"obj":"Chemical"},{"id":"T15459","span":{"begin":136,"end":141},"obj":"Chemical"},{"id":"T98235","span":{"begin":174,"end":178},"obj":"Chemical"},{"id":"T61651","span":{"begin":229,"end":231},"obj":"Chemical"},{"id":"T10468","span":{"begin":233,"end":249},"obj":"Chemical"},{"id":"T33326","span":{"begin":245,"end":249},"obj":"Chemical"},{"id":"T93741","span":{"begin":251,"end":254},"obj":"Chemical"},{"id":"T49022","span":{"begin":266,"end":272},"obj":"Chemical"},{"id":"T32999","span":{"begin":295,"end":298},"obj":"Chemical"},{"id":"T44466","span":{"begin":300,"end":310},"obj":"Chemical"},{"id":"T12742","span":{"begin":317,"end":320},"obj":"Chemical"},{"id":"T92319","span":{"begin":322,"end":342},"obj":"Chemical"},{"id":"T3064","span":{"begin":338,"end":342},"obj":"Chemical"},{"id":"T14197","span":{"begin":349,"end":375},"obj":"Chemical"},{"id":"T66732","span":{"begin":371,"end":375},"obj":"Chemical"},{"id":"T292","span":{"begin":377,"end":380},"obj":"Chemical"},{"id":"T45166","span":{"begin":382,"end":408},"obj":"Chemical"},{"id":"T89769","span":{"begin":404,"end":408},"obj":"Chemical"},{"id":"T46951","span":{"begin":410,"end":413},"obj":"Chemical"},{"id":"T32094","span":{"begin":415,"end":436},"obj":"Chemical"},{"id":"T89321","span":{"begin":432,"end":436},"obj":"Chemical"}],"attributes":[{"id":"A38971","pred":"chebi_id","subj":"T41515","obj":"http://purl.obolibrary.org/obo/CHEBI_26208"},{"id":"A4581","pred":"chebi_id","subj":"T49437","obj":"http://purl.obolibrary.org/obo/CHEBI_16016"},{"id":"A58554","pred":"chebi_id","subj":"T49437","obj":"http://purl.obolibrary.org/obo/CHEBI_28125"},{"id":"A82039","pred":"chebi_id","subj":"T49437","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A35363","pred":"chebi_id","subj":"T49437","obj":"http://purl.obolibrary.org/obo/CHEBI_36005"},{"id":"A6733","pred":"chebi_id","subj":"T8273","obj":"http://purl.obolibrary.org/obo/CHEBI_28364"},{"id":"A21568","pred":"chebi_id","subj":"T273","obj":"http://purl.obolibrary.org/obo/CHEBI_38559"},{"id":"A92764","pred":"chebi_id","subj":"T15459","obj":"http://purl.obolibrary.org/obo/CHEBI_26208"},{"id":"A19285","pred":"chebi_id","subj":"T98235","obj":"http://purl.obolibrary.org/obo/CHEBI_140399"},{"id":"A62200","pred":"chebi_id","subj":"T61651","obj":"http://purl.obolibrary.org/obo/CHEBI_15843"},{"id":"A59023","pred":"chebi_id","subj":"T61651","obj":"http://purl.obolibrary.org/obo/CHEBI_72816"},{"id":"A29753","pred":"chebi_id","subj":"T10468","obj":"http://purl.obolibrary.org/obo/CHEBI_15843"},{"id":"A22938","pred":"chebi_id","subj":"T33326","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A84220","pred":"chebi_id","subj":"T93741","obj":"http://purl.obolibrary.org/obo/CHEBI_3478"},{"id":"A88587","pred":"chebi_id","subj":"T49022","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A46688","pred":"chebi_id","subj":"T32999","obj":"http://purl.obolibrary.org/obo/CHEBI_38559"},{"id":"A8202","pred":"chebi_id","subj":"T44466","obj":"http://purl.obolibrary.org/obo/CHEBI_4056"},{"id":"A10640","pred":"chebi_id","subj":"T12742","obj":"http://purl.obolibrary.org/obo/CHEBI_16016"},{"id":"A5446","pred":"chebi_id","subj":"T12742","obj":"http://purl.obolibrary.org/obo/CHEBI_28125"},{"id":"A81270","pred":"chebi_id","subj":"T12742","obj":"http://purl.obolibrary.org/obo/CHEBI_28689"},{"id":"A45576","pred":"chebi_id","subj":"T12742","obj":"http://purl.obolibrary.org/obo/CHEBI_36005"},{"id":"A47508","pred":"chebi_id","subj":"T92319","obj":"http://purl.obolibrary.org/obo/CHEBI_28125"},{"id":"A88988","pred":"chebi_id","subj":"T3064","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A6172","pred":"chebi_id","subj":"T14197","obj":"http://purl.obolibrary.org/obo/CHEBI_72654"},{"id":"A63515","pred":"chebi_id","subj":"T66732","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A52287","pred":"chebi_id","subj":"T292","obj":"http://purl.obolibrary.org/obo/CHEBI_144559"},{"id":"A30987","pred":"chebi_id","subj":"T292","obj":"http://purl.obolibrary.org/obo/CHEBI_72852"},{"id":"A90870","pred":"chebi_id","subj":"T45166","obj":"http://purl.obolibrary.org/obo/CHEBI_72852"},{"id":"A28090","pred":"chebi_id","subj":"T89769","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"id":"A78562","pred":"chebi_id","subj":"T46951","obj":"http://purl.obolibrary.org/obo/CHEBI_28364"},{"id":"A91934","pred":"chebi_id","subj":"T32094","obj":"http://purl.obolibrary.org/obo/CHEBI_28364"},{"id":"A11666","pred":"chebi_id","subj":"T89321","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":". (D) N-3 PUFAs, DHA and EPA, are metabolized by CYP epoxygenases into bioactive epoxylipids with anti-inflammatory properties. (E) N-3 PUFAs are metabolized by COX/LOX into SPMs which act as potent anti-inflammatory modulators. AA, Arachidonic acid; CCL, Chemokine ligand; COX, Cyclooxygenase; CYP, Cytochrome P450; DHA, Docosahexaenoic acid; EDP, Epoxydocosapentaenoic acid; EEQ, Epoxyeicosatetraenoic acid; EPA, Eicosapentaenoic acid;"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T125","span":{"begin":300,"end":310},"obj":"http://purl.obolibrary.org/obo/GO_0045158"},{"id":"T126","span":{"begin":300,"end":310},"obj":"http://purl.obolibrary.org/obo/GO_0045157"},{"id":"T127","span":{"begin":300,"end":310},"obj":"http://purl.obolibrary.org/obo/GO_0045156"},{"id":"T128","span":{"begin":300,"end":310},"obj":"http://purl.obolibrary.org/obo/GO_0008121"}],"text":". (D) N-3 PUFAs, DHA and EPA, are metabolized by CYP epoxygenases into bioactive epoxylipids with anti-inflammatory properties. (E) N-3 PUFAs are metabolized by COX/LOX into SPMs which act as potent anti-inflammatory modulators. AA, Arachidonic acid; CCL, Chemokine ligand; COX, Cyclooxygenase; CYP, Cytochrome P450; DHA, Docosahexaenoic acid; EDP, Epoxydocosapentaenoic acid; EEQ, Epoxyeicosatetraenoic acid; EPA, Eicosapentaenoic acid;"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1936","span":{"begin":295,"end":298},"obj":"Gene"},{"id":"1937","span":{"begin":300,"end":315},"obj":"Gene"},{"id":"1948","span":{"begin":49,"end":52},"obj":"Gene"},{"id":"1950","span":{"begin":6,"end":15},"obj":"Chemical"},{"id":"1951","span":{"begin":17,"end":20},"obj":"Chemical"},{"id":"1952","span":{"begin":25,"end":28},"obj":"Chemical"},{"id":"1953","span":{"begin":132,"end":141},"obj":"Chemical"}],"attributes":[{"id":"A1936","pred":"tao:has_database_id","subj":"1936","obj":"Gene:4051"},{"id":"A1937","pred":"tao:has_database_id","subj":"1937","obj":"Gene:4051"},{"id":"A1948","pred":"tao:has_database_id","subj":"1948","obj":"Gene:4051"},{"id":"A1950","pred":"tao:has_database_id","subj":"1950","obj":"MESH:D015525"},{"id":"A1951","pred":"tao:has_database_id","subj":"1951","obj":"MESH:D004281"},{"id":"A1952","pred":"tao:has_database_id","subj":"1952","obj":"MESH:D015118"},{"id":"A1953","pred":"tao:has_database_id","subj":"1953","obj":"MESH:D015525"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":". (D) N-3 PUFAs, DHA and EPA, are metabolized by CYP epoxygenases into bioactive epoxylipids with anti-inflammatory properties. (E) N-3 PUFAs are metabolized by COX/LOX into SPMs which act as potent anti-inflammatory modulators. AA, Arachidonic acid; CCL, Chemokine ligand; COX, Cyclooxygenase; CYP, Cytochrome P450; DHA, Docosahexaenoic acid; EDP, Epoxydocosapentaenoic acid; EEQ, Epoxyeicosatetraenoic acid; EPA, Eicosapentaenoic acid;"}