PMC:7534795 / 62648-63646
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T252 | 769-775 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T90 | 769-775 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T425 | 76-84 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T426 | 363-379 | Disease | denotes | viral infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
| T427 | 802-814 | Disease | denotes | coagulopathy | http://purl.obolibrary.org/obo/MONDO_0001531 |
| T428 | 950-962 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T429 | 989-997 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T374 | 87-88 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T375 | 202-203 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T376 | 407-415 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
| T377 | 458-468 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activating |
| T378 | 688-693 | http://purl.obolibrary.org/obo/CLO_0037161 | denotes | (E) N |
| T379 | 911-912 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T80175 | 52-57 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T24234 | 94-99 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T7018 | 209-214 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T98746 | 324-329 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T70497 | 530-535 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T32324 | 696-701 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T84667 | 710-721 | Chemical | denotes | antioxidant | http://purl.obolibrary.org/obo/CHEBI_22586 |
| T12453 | 785-790 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
| T24148 | 860-872 | Chemical | denotes | triglyceride | http://purl.obolibrary.org/obo/CHEBI_17855 |
| T15454 | 896-901 | Chemical | denotes | PUFAs | http://purl.obolibrary.org/obo/CHEBI_26208 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T110 | 124-140 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune responses |
| T111 | 299-314 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
| T112 | 363-379 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infections |
| T113 | 950-962 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T474 | 0-998 | Sentence | denotes | Fig. 2 Potential cardioprotective mechanisms of n-3 PUFAs in the setting of COVID-19. (A) N-3 PUFAs ameliorate uncontrolled immune responses and exert anti-inflammatory effects via several mechanisms. (B) N-3 PUFAs attenuate the vicious cycle/interaction of mitochondrial dysfunction and aggravated immune response. (C) N-3 PUFAs have the capability to attenuate viral infections via both direct effects on membrane integrity and indirect mechanisms through activating the humoral response to decrease overall viral load. (D) N-3 PUFAs have the ability to regulate the RAAS system in the favor of the vasodilatory, the anti-inflammatory and the cardioprotective ACE2/Ang (1–7) effectors. (E) N-3 PUFAs enhance antioxidant capacity and attenuate oxidative stress in the tissue. (F) N-3 PUFAs ameliorate coagulopathy by exerting anti-thrombotic effects. (G) The triglyceride-lowering effect of n-3 PUFAs may play a key role in blunting the exaggerated inflammation observed in patients with COVID-19. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T200 | 258-283 | Phenotype | denotes | mitochondrial dysfunction | http://purl.obolibrary.org/obo/HP_0003287 |
| T201 | 745-761 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
| T202 | 802-814 | Phenotype | denotes | coagulopathy | http://purl.obolibrary.org/obo/HP_0003256 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1848 | 662-666 | Gene | denotes | ACE2 | Gene:59272 |
| 1857 | 975-983 | Species | denotes | patients | Tax:9606 |
| 1858 | 90-99 | Chemical | denotes | N-3 PUFAs | MESH:D015525 |
| 1859 | 205-214 | Chemical | denotes | N-3 PUFAs | MESH:D015525 |
| 1860 | 526-535 | Chemical | denotes | N-3 PUFAs | MESH:D015525 |
| 1861 | 692-701 | Chemical | denotes | N-3 PUFAs | MESH:D015525 |
| 1862 | 781-790 | Chemical | denotes | N-3 PUFAs | MESH:D015525 |
| 1863 | 860-872 | Chemical | denotes | triglyceride | MESH:D014280 |
| 1870 | 76-84 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 1871 | 258-283 | Disease | denotes | mitochondrial dysfunction | MESH:D028361 |
| 1872 | 363-379 | Disease | denotes | viral infections | MESH:D001102 |
| 1873 | 802-814 | Disease | denotes | coagulopathy | MESH:D001778 |
| 1874 | 950-962 | Disease | denotes | inflammation | MESH:D007249 |
| 1875 | 989-997 | Disease | denotes | COVID-19 | MESH:C000657245 |