PMC:7534795 / 6145-6443 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T90573","span":{"begin":19,"end":27},"obj":"Body_part"},{"id":"T84940","span":{"begin":144,"end":155},"obj":"Body_part"},{"id":"T2963","span":{"begin":156,"end":166},"obj":"Body_part"},{"id":"T89453","span":{"begin":197,"end":200},"obj":"Body_part"},{"id":"T80835","span":{"begin":218,"end":221},"obj":"Body_part"},{"id":"T16035","span":{"begin":268,"end":279},"obj":"Body_part"}],"attributes":[{"id":"A37735","pred":"fma_id","subj":"T90573","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A8018","pred":"fma_id","subj":"T84940","obj":"http://purl.org/sig/ont/fma/fma62854"},{"id":"A79436","pred":"fma_id","subj":"T2963","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A20235","pred":"fma_id","subj":"T89453","obj":"http://purl.org/sig/ont/fma/fma20935"},{"id":"A13646","pred":"fma_id","subj":"T80835","obj":"http://purl.org/sig/ont/fma/fma20935"},{"id":"A20919","pred":"fma_id","subj":"T16035","obj":"http://purl.org/sig/ont/fma/fma63261"}],"text":"eutic potential in cytokine storm, given its effectiveness on patient survival in severe sepsis (Alijotas-Reig et al., 2020; Rizk et al., 2020)\nGranulocyte-macrophage-colony stimulating factor (GM-CSF) inhibition • GM-CSF can play a pro-inflammatory role signaling to macrophages\n• COVID-19 patient"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T54","span":{"begin":282,"end":290},"obj":"Disease"}],"attributes":[{"id":"A54","pred":"mondo_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"}],"text":"eutic potential in cytokine storm, given its effectiveness on patient survival in severe sepsis (Alijotas-Reig et al., 2020; Rizk et al., 2020)\nGranulocyte-macrophage-colony stimulating factor (GM-CSF) inhibition • GM-CSF can play a pro-inflammatory role signaling to macrophages\n• COVID-19 patient"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T23727","span":{"begin":231,"end":232},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T5199","span":{"begin":255,"end":264},"obj":"http://purl.obolibrary.org/obo/SO_0000418"}],"text":"eutic potential in cytokine storm, given its effectiveness on patient survival in severe sepsis (Alijotas-Reig et al., 2020; Rizk et al., 2020)\nGranulocyte-macrophage-colony stimulating factor (GM-CSF) inhibition • GM-CSF can play a pro-inflammatory role signaling to macrophages\n• COVID-19 patient"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T57","span":{"begin":194,"end":196},"obj":"Chemical"},{"id":"T58","span":{"begin":215,"end":217},"obj":"Chemical"}],"attributes":[{"id":"A57","pred":"chebi_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/CHEBI_74120"},{"id":"A58","pred":"chebi_id","subj":"T58","obj":"http://purl.obolibrary.org/obo/CHEBI_74120"}],"text":"eutic potential in cytokine storm, given its effectiveness on patient survival in severe sepsis (Alijotas-Reig et al., 2020; Rizk et al., 2020)\nGranulocyte-macrophage-colony stimulating factor (GM-CSF) inhibition • GM-CSF can play a pro-inflammatory role signaling to macrophages\n• COVID-19 patient"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T38785","span":{"begin":255,"end":264},"obj":"http://purl.obolibrary.org/obo/GO_0023052"}],"text":"eutic potential in cytokine storm, given its effectiveness on patient survival in severe sepsis (Alijotas-Reig et al., 2020; Rizk et al., 2020)\nGranulocyte-macrophage-colony stimulating factor (GM-CSF) inhibition • GM-CSF can play a pro-inflammatory role signaling to macrophages\n• COVID-19 patient"}

{"project":"LitCovid-sentences","denotations":[{"id":"T34","span":{"begin":144,"end":279},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"eutic potential in cytokine storm, given its effectiveness on patient survival in severe sepsis (Alijotas-Reig et al., 2020; Rizk et al., 2020)\nGranulocyte-macrophage-colony stimulating factor (GM-CSF) inhibition • GM-CSF can play a pro-inflammatory role signaling to macrophages\n• COVID-19 patient"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T23","span":{"begin":19,"end":33},"obj":"Phenotype"},{"id":"T24","span":{"begin":89,"end":95},"obj":"Phenotype"}],"attributes":[{"id":"A23","pred":"hp_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/HP_0033041"},{"id":"A24","pred":"hp_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/HP_0100806"}],"text":"eutic potential in cytokine storm, given its effectiveness on patient survival in severe sepsis (Alijotas-Reig et al., 2020; Rizk et al., 2020)\nGranulocyte-macrophage-colony stimulating factor (GM-CSF) inhibition • GM-CSF can play a pro-inflammatory role signaling to macrophages\n• COVID-19 patient"}

{"project":"2_test","denotations":[{"id":"33031856-32696108-84038809","span":{"begin":138,"end":142},"obj":"32696108"},{"id":"33031856-32696108-84038811","span":{"begin":138,"end":142},"obj":"32696108"}],"text":"eutic potential in cytokine storm, given its effectiveness on patient survival in severe sepsis (Alijotas-Reig et al., 2020; Rizk et al., 2020)\nGranulocyte-macrophage-colony stimulating factor (GM-CSF) inhibition • GM-CSF can play a pro-inflammatory role signaling to macrophages\n• COVID-19 patient"}

{"project":"LitCovid-PubTator","denotations":[{"id":"166","span":{"begin":144,"end":192},"obj":"Gene"},{"id":"167","span":{"begin":194,"end":200},"obj":"Gene"},{"id":"178","span":{"begin":62,"end":69},"obj":"Species"},{"id":"180","span":{"begin":215,"end":221},"obj":"Gene"},{"id":"193","span":{"begin":89,"end":95},"obj":"Disease"},{"id":"194","span":{"begin":268,"end":290},"obj":"Disease"}],"attributes":[{"id":"A166","pred":"tao:has_database_id","subj":"166","obj":"Gene:1437"},{"id":"A167","pred":"tao:has_database_id","subj":"167","obj":"Gene:1437"},{"id":"A178","pred":"tao:has_database_id","subj":"178","obj":"Tax:9606"},{"id":"A180","pred":"tao:has_database_id","subj":"180","obj":"Gene:1437"},{"id":"A193","pred":"tao:has_database_id","subj":"193","obj":"MESH:D018805"},{"id":"A194","pred":"tao:has_database_id","subj":"194","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"eutic potential in cytokine storm, given its effectiveness on patient survival in severe sepsis (Alijotas-Reig et al., 2020; Rizk et al., 2020)\nGranulocyte-macrophage-colony stimulating factor (GM-CSF) inhibition • GM-CSF can play a pro-inflammatory role signaling to macrophages\n• COVID-19 patient"}