PMC:7534795 / 36918-37889
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T288 | 31-43 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T289 | 188-194 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T290 | 541-544 | Disease | denotes | ARB | http://purl.obolibrary.org/obo/MONDO_0012733 |
| T291 | 684-690 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T253 | 364-365 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T282 | 207-213 | Chemical | denotes | statin | http://purl.obolibrary.org/obo/CHEBI_87631 |
| T283 | 236-242 | Chemical | denotes | statin | http://purl.obolibrary.org/obo/CHEBI_87631 |
| T284 | 257-263 | Chemical | denotes | statin | http://purl.obolibrary.org/obo/CHEBI_87631 |
| T285 | 270-282 | Chemical | denotes | Atorvastatin | http://purl.obolibrary.org/obo/CHEBI_39548 |
| T286 | 338-345 | Chemical | denotes | statins | http://purl.obolibrary.org/obo/CHEBI_87631 |
| T287 | 391-403 | Chemical | denotes | atorvastatin | http://purl.obolibrary.org/obo/CHEBI_39548 |
| T288 | 469-475 | Chemical | denotes | statin | http://purl.obolibrary.org/obo/CHEBI_87631 |
| T289 | 568-574 | Chemical | denotes | statin | http://purl.obolibrary.org/obo/CHEBI_87631 |
| T290 | 620-626 | Chemical | denotes | statin | http://purl.obolibrary.org/obo/CHEBI_87631 |
| T291 | 719-721 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T293 | 738-744 | Chemical | denotes | statin | http://purl.obolibrary.org/obo/CHEBI_87631 |
| T294 | 851-857 | Chemical | denotes | statin | http://purl.obolibrary.org/obo/CHEBI_87631 |
| T295 | 930-937 | Chemical | denotes | statins | http://purl.obolibrary.org/obo/CHEBI_87631 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T91 | 31-43 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T256 | 0-94 | Sentence | denotes | • Statin therapy and impact on inflammation and patient prognosis • Retrospective cohort study |
| T257 | 95-143 | Sentence | denotes | • Primary endpoint of 28-day all-cause mortality |
| T258 | 144-194 | Sentence | denotes | • Secondary endpoint included acute cardiac injury |
| T259 | 195-217 | Sentence | denotes | • N = 1219 statin use |
| T260 | 218-267 | Sentence | denotes | • N = 12, 762 no statin • In-hospital statin use |
| T261 | 268-289 | Sentence | denotes | • Atorvastatin 83.2%, |
| T262 | 290-310 | Sentence | denotes | • Rosuvastatin 15.6% |
| T263 | 311-521 | Sentence | denotes | • Dose differences between statins were converted to a daily equivalent dose of atorvastatin ranging from 18.9–20.0 mg/day • Reduced all-cause mortality with statin use hazard ratio (HR) 0.63 (95% CI 0.48–0.84) |
| T264 | 522-632 | Sentence | denotes | • Patients on ACEi/ARB therapy in addition to statin did not have increased mortality compared to statin alone |
| T265 | 633-690 | Sentence | denotes | • Statin therapy not associated with acute cardiac injury |
| T266 | 691-971 | Sentence | denotes | • Inflammatory markers CRP, IL-6 were lower in statin treated patients while in hospital • Reduced mortality and improved prognosis associated with in-hospital statin use may be due to the anti-inflammatory and immunomodulatory effects of statins (Zhang, Qin, Cheng, et al., 2020) |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1183 | 714-717 | Gene | denotes | CRP | Gene:1401 |
| 1184 | 719-723 | Gene | denotes | IL-6 | Gene:3569 |
| 1186 | 48-55 | Species | denotes | patient | Tax:9606 |
| 1187 | 524-532 | Species | denotes | Patients | Tax:9606 |
| 1188 | 753-761 | Species | denotes | patients | Tax:9606 |
| 1202 | 31-43 | Disease | denotes | inflammation | MESH:D007249 |
| 1203 | 180-199 | Disease | denotes | cardiac injury • N | MESH:D006331 |
| 1204 | 454-463 | Disease | denotes | mortality | MESH:D003643 |
| 1205 | 598-607 | Disease | denotes | mortality | MESH:D003643 |
| 1206 | 676-705 | Disease | denotes | cardiac injury • Inflammatory | MESH:D006331 |
| 1207 | 790-799 | Disease | denotes | mortality | MESH:D003643 |