PMC:7534795 / 104520-105999 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T34 414-422 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T35 1004-1009 Body_part denotes Heart http://purl.org/sig/ont/fma/fma7088
T36 1078-1083 Body_part denotes Heart http://purl.org/sig/ont/fma/fma7088

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T137 1004-1009 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948
T138 1078-1083 Body_part denotes Heart http://purl.obolibrary.org/obo/UBERON_0000948

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T575 127-135 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T576 264-272 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T577 457-465 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T578 476-482 Disease denotes injury http://purl.obolibrary.org/obo/MONDO_0021178
T579 576-584 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T580 599-611 Disease denotes hypertension http://purl.obolibrary.org/obo/MONDO_0005044
T581 682-690 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T582 894-902 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T583 1023-1026 Disease denotes AHA http://purl.obolibrary.org/obo/MONDO_0020108
T584 1078-1091 Disease denotes Heart Failure http://purl.obolibrary.org/obo/MONDO_0005252
T585 1308-1316 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T586 1319-1328 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T587 1461-1469 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T55 62-70 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T56 412-413 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T57 490-492 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T58 490-492 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T59 522-523 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T60 970-971 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T61 1004-1009 http://purl.obolibrary.org/obo/UBERON_0000948 denotes Heart
T62 1004-1009 http://purl.obolibrary.org/obo/UBERON_0007100 denotes Heart
T63 1004-1009 http://purl.obolibrary.org/obo/UBERON_0015228 denotes Heart
T64 1004-1009 http://www.ebi.ac.uk/efo/EFO_0000815 denotes Heart
T65 1078-1083 http://purl.obolibrary.org/obo/UBERON_0000948 denotes Heart
T66 1078-1083 http://purl.obolibrary.org/obo/UBERON_0007100 denotes Heart
T67 1078-1083 http://purl.obolibrary.org/obo/UBERON_0015228 denotes Heart
T68 1078-1083 http://www.ebi.ac.uk/efo/EFO_0000815 denotes Heart
T69 1343-1344 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T8642 214-228 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T64765 218-228 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T98256 490-492 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T99 618-632 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T58213 622-632 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T47825 717-731 Chemical denotes ACE inhibitors http://purl.obolibrary.org/obo/CHEBI_35457
T12352 721-731 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T22206 843-852 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T31919 1023-1026 Chemical denotes AHA http://purl.obolibrary.org/obo/CHEBI_27777
T30574 1065-1068 Chemical denotes ACC http://purl.obolibrary.org/obo/CHEBI_18053|http://purl.obolibrary.org/obo/CHEBI_30526
T36552 1148-1161 Chemical denotes ACE inhibitor http://purl.obolibrary.org/obo/CHEBI_35457
T48816 1152-1161 Chemical denotes inhibitor http://purl.obolibrary.org/obo/CHEBI_35222
T31232 1261-1263 Chemical denotes II http://purl.obolibrary.org/obo/CHEBI_74067

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T13 1368-1389 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T14 1394-1410 http://purl.obolibrary.org/obo/GO_0042310 denotes vasoconstriction

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T652 0-169 Sentence denotes Importantly, evidence demonstrating upregulation and enhanced activity of ACE2 suggested it will facilitate the infectivity of SARS-CoV-2 (South, Diz, & Chappell, 2020).
T653 170-316 Sentence denotes Accordingly, some researchers proposed that ACE inhibitors and ARBs should be discontinued in COVID-19 patients (Diaz, 2020; Esler & Esler, 2020).
T654 317-521 Sentence denotes However, in addition to the direct effects on cardiac ACE2 other mechanisms such as triggering a cytokine storm will markedly contribute to SARS-CoV-2-induced injury (Chen, Li, Chen, Feng, & Xiong, 2020).
T655 522-757 Sentence denotes A recent study conducted by Yang et al., demonstrated COVID-19 patients with hypertension using ACE inhibitors/ARBs had lower mortality rates than hypertensive COVID-19 patients that were not on ACE inhibitors/ARBs (Yang et al., 2020).
T656 758-954 Sentence denotes Moreover, Mancia et al. examined 6272 patients and found no association between RAAS inhibitor use and susceptibility or development of COVID-19 (Mancia, Rea, Ludergnani, Apolone, & Corrao, 2020).
T657 955-1199 Sentence denotes In that sense, a published statement by American Heart Association (AHA), the American College of Cardiology (ACC) and the Heart Failure Society of America strongly recommended continuation of ACE inhibitor/ARBs (Zhang, Zhu, Cai, et al., 2020).
T658 1200-1479 Sentence denotes Together, these data suggest therapies targeting ACE and Ang II do not appear to increase the likelihood of SARS-CoV-2 infection, but may have a role in abrogating the inflammatory response and vasoconstriction that contributes to the clinical deterioration in COVID-19 patients.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T234 414-428 Phenotype denotes cytokine storm http://purl.obolibrary.org/obo/HP_0033041
T235 599-611 Phenotype denotes hypertension http://purl.obolibrary.org/obo/HP_0000822
T236 1078-1091 Phenotype denotes Heart Failure http://purl.obolibrary.org/obo/HP_0001635

2_test

Id Subject Object Predicate Lexical cue
33031856-32228252-84039124 163-167 32228252 denotes 2020
33031856-32195824-84039125 310-314 32195824 denotes 2020
33031856-32227090-84039126 515-519 32227090 denotes 2020
33031856-32348166-84039127 751-755 32348166 denotes 2020
33031856-32356627-84039128 948-952 32356627 denotes 2020
33031856-32302265-84039129 1193-1197 32302265 denotes 2020

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2956 74-78 Gene denotes ACE2 Gene:59272
2957 214-217 Gene denotes ACE Gene:1636
2958 371-375 Gene denotes ACE2 Gene:59272
2959 618-621 Gene denotes ACE Gene:1636
2960 717-720 Gene denotes ACE Gene:1636
2961 1148-1151 Gene denotes ACE Gene:1636
2962 1249-1252 Gene denotes ACE Gene:1636
2963 127-137 Species denotes SARS-CoV-2 Tax:2697049
2964 273-281 Species denotes patients Tax:9606
2965 457-467 Species denotes SARS-CoV-2 Tax:2697049
2966 585-593 Species denotes patients Tax:9606
2967 691-699 Species denotes patients Tax:9606
2968 796-804 Species denotes patients Tax:9606
2969 1470-1478 Species denotes patients Tax:9606
2970 264-272 Disease denotes COVID-19 MESH:C000657245
2971 576-584 Disease denotes COVID-19 MESH:C000657245
2972 599-611 Disease denotes hypertension MESH:D006973
2973 648-657 Disease denotes mortality MESH:D003643
2974 669-681 Disease denotes hypertensive MESH:D006973
2975 682-690 Disease denotes COVID-19 MESH:C000657245
2976 894-902 Disease denotes COVID-19 MESH:C000657245
2977 1023-1026 Disease denotes AHA
2978 1308-1328 Disease denotes SARS-CoV-2 infection MESH:C000657245
2979 1461-1469 Disease denotes COVID-19 MESH:C000657245