PMC:7534206 / 155-1260
Annnotations
{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/7534206","sourcedb":"PMC","sourceid":"7534206","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7534206","text":"al manifestations including stroke.\n\nObjectives\nWe present a case series of coronavirus disease 2019 patients from two institutions with acute cerebrovascular pathologies. In addition, we present a pooled analysis of published data on large vessel occlusion in the setting of coronavirus disease 2019 and a concise summary of the pathophysiology of acute cerebrovascular disease in the setting of coronavirus disease 2019.\n\nMethods\nA retrospective study across two institutions was conducted between 20 March 2020 and 20 May 2020, for patients developing acute cerebrovascular disease and diagnosed with coronavirus disease 2019. We performed a literature review using the PubMed search engine.\n\nResults\nThe total sample size was 22 patients. The mean age was 59.5 years, and 12 patients were female. The cerebrovascular pathologies were 17 cases of acute ischemic stroke, 3 cases of aneurysm rupture, and 2 cases of sinus thrombosis. Of the stroke and sinus thrombosis patients, the mean National Institute of Health Stroke Scale was 13.8 ± 8.0, and 16 (84.2%) patients underwent a mechanical thrombectom","divisions":[{"label":"sec","span":{"begin":37,"end":422}},{"label":"title","span":{"begin":37,"end":47}},{"label":"p","span":{"begin":48,"end":422}},{"label":"sec","span":{"begin":424,"end":694}},{"label":"title","span":{"begin":424,"end":431}},{"label":"p","span":{"begin":432,"end":694}},{"label":"title","span":{"begin":696,"end":703}}],"tracks":[{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":241,"end":247},"obj":"Body_part"},{"id":"T2","span":{"begin":1025,"end":1030},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000055"},{"id":"A2","pred":"uberon_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/UBERON_0002542"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T3","span":{"begin":28,"end":34},"obj":"Disease"},{"id":"T5","span":{"begin":76,"end":100},"obj":"Disease"},{"id":"T6","span":{"begin":276,"end":300},"obj":"Disease"},{"id":"T7","span":{"begin":355,"end":378},"obj":"Disease"},{"id":"T8","span":{"begin":397,"end":421},"obj":"Disease"},{"id":"T9","span":{"begin":561,"end":584},"obj":"Disease"},{"id":"T10","span":{"begin":604,"end":628},"obj":"Disease"},{"id":"T11","span":{"begin":865,"end":871},"obj":"Disease"},{"id":"T13","span":{"begin":923,"end":933},"obj":"Disease"},{"id":"T14","span":{"begin":942,"end":948},"obj":"Disease"},{"id":"T16","span":{"begin":959,"end":969},"obj":"Disease"},{"id":"T17","span":{"begin":1018,"end":1024},"obj":"Disease"}],"attributes":[{"id":"A3","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0005098"},{"id":"A4","pred":"mondo_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/MONDO_0011057"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0011057"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0011057"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005098"},{"id":"A12","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0011057"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0000831"},{"id":"A14","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0005098"},{"id":"A15","pred":"mondo_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/MONDO_0011057"},{"id":"A16","pred":"mondo_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/MONDO_0000831"},{"id":"A17","pred":"mondo_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/MONDO_0005098"},{"id":"A18","pred":"mondo_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/MONDO_0011057"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T9","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T10","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T11","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T13","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T14","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T16","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T17","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1","span":{"begin":37,"end":47},"obj":"http://purl.obolibrary.org/obo/BFO_0000030"},{"id":"T2","span":{"begin":59,"end":60},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T3","span":{"begin":196,"end":197},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T4","span":{"begin":241,"end":247},"obj":"http://purl.obolibrary.org/obo/UBERON_0000055"},{"id":"T5","span":{"begin":305,"end":306},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T6","span":{"begin":432,"end":433},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T7","span":{"begin":643,"end":644},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T8","span":{"begin":730,"end":732},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"},{"id":"T9","span":{"begin":793,"end":799},"obj":"http://purl.obolibrary.org/obo/UBERON_0003100"},{"id":"T10","span":{"begin":1081,"end":1082},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T9","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T10","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T1","span":{"begin":28,"end":34},"obj":"Phenotype"},{"id":"T2","span":{"begin":856,"end":871},"obj":"Phenotype"},{"id":"T3","span":{"begin":884,"end":892},"obj":"Phenotype"},{"id":"T4","span":{"begin":942,"end":948},"obj":"Phenotype"},{"id":"T5","span":{"begin":1018,"end":1024},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/HP_0001297"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/HP_0002140"},{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0002617"},{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0001297"},{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0001297"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T5","span":{"begin":37,"end":47},"obj":"Sentence"},{"id":"T6","span":{"begin":48,"end":171},"obj":"Sentence"},{"id":"T7","span":{"begin":172,"end":422},"obj":"Sentence"},{"id":"T8","span":{"begin":424,"end":431},"obj":"Sentence"},{"id":"T9","span":{"begin":432,"end":629},"obj":"Sentence"},{"id":"T10","span":{"begin":630,"end":694},"obj":"Sentence"},{"id":"T11","span":{"begin":696,"end":703},"obj":"Sentence"},{"id":"T12","span":{"begin":704,"end":742},"obj":"Sentence"},{"id":"T13","span":{"begin":743,"end":800},"obj":"Sentence"},{"id":"T14","span":{"begin":801,"end":934},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T5","pred":"source","obj":"LitCovid-sentences"},{"subj":"T6","pred":"source","obj":"LitCovid-sentences"},{"subj":"T7","pred":"source","obj":"LitCovid-sentences"},{"subj":"T8","pred":"source","obj":"LitCovid-sentences"},{"subj":"T9","pred":"source","obj":"LitCovid-sentences"},{"subj":"T10","pred":"source","obj":"LitCovid-sentences"},{"subj":"T11","pred":"source","obj":"LitCovid-sentences"},{"subj":"T12","pred":"source","obj":"LitCovid-sentences"},{"subj":"T13","pred":"source","obj":"LitCovid-sentences"},{"subj":"T14","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"9","span":{"begin":28,"end":34},"obj":"Disease"},{"id":"16","span":{"begin":101,"end":109},"obj":"Species"},{"id":"17","span":{"begin":76,"end":100},"obj":"Disease"},{"id":"18","span":{"begin":143,"end":170},"obj":"Disease"},{"id":"19","span":{"begin":276,"end":300},"obj":"Disease"},{"id":"20","span":{"begin":349,"end":378},"obj":"Disease"},{"id":"21","span":{"begin":397,"end":421},"obj":"Disease"},{"id":"25","span":{"begin":535,"end":543},"obj":"Species"},{"id":"26","span":{"begin":555,"end":584},"obj":"Disease"},{"id":"27","span":{"begin":604,"end":628},"obj":"Disease"},{"id":"48","span":{"begin":733,"end":741},"obj":"Species"},{"id":"49","span":{"begin":779,"end":787},"obj":"Species"},{"id":"50","span":{"begin":970,"end":978},"obj":"Species"},{"id":"51","span":{"begin":1062,"end":1070},"obj":"Species"},{"id":"57","span":{"begin":805,"end":832},"obj":"Disease"},{"id":"58","span":{"begin":856,"end":871},"obj":"Disease"},{"id":"59","span":{"begin":884,"end":900},"obj":"Disease"},{"id":"60","span":{"begin":917,"end":933},"obj":"Disease"},{"id":"61","span":{"begin":942,"end":948},"obj":"Disease"},{"id":"62","span":{"begin":953,"end":969},"obj":"Disease"},{"id":"63","span":{"begin":1018,"end":1024},"obj":"Disease"}],"attributes":[{"id":"A9","pred":"tao:has_database_id","subj":"9","obj":"MESH:D020521"},{"id":"A16","pred":"tao:has_database_id","subj":"16","obj":"Tax:9606"},{"id":"A17","pred":"tao:has_database_id","subj":"17","obj":"MESH:C000657245"},{"id":"A18","pred":"tao:has_database_id","subj":"18","obj":"MESH:D002561"},{"id":"A19","pred":"tao:has_database_id","subj":"19","obj":"MESH:C000657245"},{"id":"A20","pred":"tao:has_database_id","subj":"20","obj":"MESH:D002561"},{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"MESH:C000657245"},{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"Tax:9606"},{"id":"A26","pred":"tao:has_database_id","subj":"26","obj":"MESH:D002561"},{"id":"A27","pred":"tao:has_database_id","subj":"27","obj":"MESH:C000657245"},{"id":"A48","pred":"tao:has_database_id","subj":"48","obj":"Tax:9606"},{"id":"A49","pred":"tao:has_database_id","subj":"49","obj":"Tax:9606"},{"id":"A50","pred":"tao:has_database_id","subj":"50","obj":"Tax:9606"},{"id":"A51","pred":"tao:has_database_id","subj":"51","obj":"Tax:9606"},{"id":"A57","pred":"tao:has_database_id","subj":"57","obj":"MESH:D002561"},{"id":"A58","pred":"tao:has_database_id","subj":"58","obj":"MESH:D002544"},{"id":"A59","pred":"tao:has_database_id","subj":"59","obj":"MESH:D017542"},{"id":"A60","pred":"tao:has_database_id","subj":"60","obj":"MESH:D012851"},{"id":"A61","pred":"tao:has_database_id","subj":"61","obj":"MESH:D020521"},{"id":"A62","pred":"tao:has_database_id","subj":"62","obj":"MESH:D012851"},{"id":"A63","pred":"tao:has_database_id","subj":"63","obj":"MESH:D020521"},{"subj":"9","pred":"source","obj":"LitCovid-PubTator"},{"subj":"16","pred":"source","obj":"LitCovid-PubTator"},{"subj":"17","pred":"source","obj":"LitCovid-PubTator"},{"subj":"18","pred":"source","obj":"LitCovid-PubTator"},{"subj":"19","pred":"source","obj":"LitCovid-PubTator"},{"subj":"20","pred":"source","obj":"LitCovid-PubTator"},{"subj":"21","pred":"source","obj":"LitCovid-PubTator"},{"subj":"25","pred":"source","obj":"LitCovid-PubTator"},{"subj":"26","pred":"source","obj":"LitCovid-PubTator"},{"subj":"27","pred":"source","obj":"LitCovid-PubTator"},{"subj":"48","pred":"source","obj":"LitCovid-PubTator"},{"subj":"49","pred":"source","obj":"LitCovid-PubTator"},{"subj":"50","pred":"source","obj":"LitCovid-PubTator"},{"subj":"51","pred":"source","obj":"LitCovid-PubTator"},{"subj":"57","pred":"source","obj":"LitCovid-PubTator"},{"subj":"58","pred":"source","obj":"LitCovid-PubTator"},{"subj":"59","pred":"source","obj":"LitCovid-PubTator"},{"subj":"60","pred":"source","obj":"LitCovid-PubTator"},{"subj":"61","pred":"source","obj":"LitCovid-PubTator"},{"subj":"62","pred":"source","obj":"LitCovid-PubTator"},{"subj":"63","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-UBERON","color":"#93a5ec","default":true},{"id":"LitCovid-PD-MONDO","color":"#bfec93"},{"id":"LitCovid-PD-CLO","color":"#ec93da"},{"id":"LitCovid-PD-HP","color":"#93ece4"},{"id":"LitCovid-sentences","color":"#ecca93"},{"id":"LitCovid-PubTator","color":"#b093ec"}]}]}}