PMC:7534206 / 0-1105
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7534206","sourcedb":"PMC","sourceid":"7534206","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7534206","text":"Cerebral ischemic and hemorrhagic complications of coronavirus disease 2019\n\nAbstract\nBackground\nThe coronavirus disease 2019 is associated with neurological manifestations including stroke.\n\nObjectives\nWe present a case series of coronavirus disease 2019 patients from two institutions with acute cerebrovascular pathologies. In addition, we present a pooled analysis of published data on large vessel occlusion in the setting of coronavirus disease 2019 and a concise summary of the pathophysiology of acute cerebrovascular disease in the setting of coronavirus disease 2019.\n\nMethods\nA retrospective study across two institutions was conducted between 20 March 2020 and 20 May 2020, for patients developing acute cerebrovascular disease and diagnosed with coronavirus disease 2019. We performed a literature review using the PubMed search engine.\n\nResults\nThe total sample size was 22 patients. The mean age was 59.5 years, and 12 patients were female. The cerebrovascular pathologies were 17 cases of acute ischemic stroke, 3 cases of aneurysm rupture, and 2 cases of sinus thrombosis. Of the stroke 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