PMC:7532482 / 6134-6732 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7532482","sourcedb":"PMC","sourceid":"7532482","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7532482","text":"In the present study, the network pharmacological was used to investigate the possible mechanism and target of SFJDC in the treatment of COVID-19. COVID-19 is a type of Novel Coronavirus Pneumonia (NCP). The active ingredients and their target genes of SFJDC were collected from TCMSP. NCP-related target genes were collected from GeneCards database. The putative mechanism of SFJDC against NCP were analyzed by GO and KEGG pathway. The flowchart of network pharmacology was shown in Figure 1. The study provided possible theoretical reference for SFJDC in the prevention and treatment of COVID-19.","tracks":[{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T41","span":{"begin":137,"end":145},"obj":"Disease"},{"id":"T42","span":{"begin":147,"end":155},"obj":"Disease"},{"id":"T43","span":{"begin":187,"end":196},"obj":"Disease"},{"id":"T44","span":{"begin":589,"end":597},"obj":"Disease"}],"attributes":[{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T47","span":{"begin":159,"end":160},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T48","span":{"begin":208,"end":214},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T49","span":{"begin":244,"end":249},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"},{"id":"T50","span":{"begin":305,"end":310},"obj":"http://purl.obolibrary.org/obo/OGG_0000000002"}],"attributes":[{"subj":"T47","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"134","span":{"begin":137,"end":145},"obj":"Disease"},{"id":"135","span":{"begin":147,"end":155},"obj":"Disease"},{"id":"136","span":{"begin":169,"end":196},"obj":"Disease"},{"id":"137","span":{"begin":589,"end":597},"obj":"Disease"}],"attributes":[{"id":"A134","pred":"tao:has_database_id","subj":"134","obj":"MESH:C000657245"},{"id":"A135","pred":"tao:has_database_id","subj":"135","obj":"MESH:C000657245"},{"id":"A136","pred":"tao:has_database_id","subj":"136","obj":"MESH:C000657245"},{"id":"A137","pred":"tao:has_database_id","subj":"137","obj":"MESH:C000657245"},{"subj":"134","pred":"source","obj":"LitCovid-PubTator"},{"subj":"135","pred":"source","obj":"LitCovid-PubTator"},{"subj":"136","pred":"source","obj":"LitCovid-PubTator"},{"subj":"137","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T16","span":{"begin":187,"end":196},"obj":"Phenotype"}],"attributes":[{"id":"A16","pred":"hp_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"subj":"T16","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T41","span":{"begin":0,"end":146},"obj":"Sentence"},{"id":"T42","span":{"begin":147,"end":203},"obj":"Sentence"},{"id":"T43","span":{"begin":204,"end":285},"obj":"Sentence"},{"id":"T44","span":{"begin":286,"end":350},"obj":"Sentence"},{"id":"T45","span":{"begin":351,"end":432},"obj":"Sentence"},{"id":"T46","span":{"begin":433,"end":493},"obj":"Sentence"},{"id":"T47","span":{"begin":494,"end":598},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T41","pred":"source","obj":"LitCovid-sentences"},{"subj":"T42","pred":"source","obj":"LitCovid-sentences"},{"subj":"T43","pred":"source","obj":"LitCovid-sentences"},{"subj":"T44","pred":"source","obj":"LitCovid-sentences"},{"subj":"T45","pred":"source","obj":"LitCovid-sentences"},{"subj":"T46","pred":"source","obj":"LitCovid-sentences"},{"subj":"T47","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-MONDO","color":"#93eca9","default":true},{"id":"LitCovid-PD-CLO","color":"#ec9397"},{"id":"LitCovid-PubTator","color":"#93b1ec"},{"id":"LitCovid-PD-HP","color":"#cbec93"},{"id":"LitCovid-sentences","color":"#ec93e5"}]}]}}