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PMC:7532482 / 153-1306 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T2 14-21 Body_part denotes capsule http://purl.org/sig/ont/fma/fma85272
T3 570-574 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T4 824-828 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T2 14-21 Body_part denotes capsule http://purl.obolibrary.org/obo/UBERON_0003893
T3 824-828 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T3 105-113 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T4 114-124 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T5 285-293 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 325-334 Disease denotes Pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T7 833-848 Disease denotes Virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T8 839-848 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T9 969-977 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 31-32 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T2 63-66 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T3 207-213 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T4 243-248 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T5 297-298 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 361-366 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T7 497-502 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T8 570-574 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T9 627-632 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T10 648-654 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T11 679-684 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T12 721-726 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T13 796-801 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T14 824-828 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T15 824-828 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T16 833-838 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T17 912-917 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 53-61 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T2 452-455 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T4 1081-1089 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T5 1091-1094 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
16 850-854 Gene denotes RELA Gene:5970
17 856-861 Gene denotes MAPK1 Gene:5594
18 863-869 Gene denotes MAPK14 Gene:1432
19 871-876 Gene denotes CASP3 Gene:836
20 878-883 Gene denotes CASP8 Gene:841
21 888-891 Gene denotes IL6 Gene:3569
22 105-113 Disease denotes COVID-19 MESH:C000657245
23 114-124 Disease denotes infections MESH:D007239
24 285-293 Disease denotes COVID-19 MESH:C000657245
25 307-334 Disease denotes Novel Coronavirus Pneumonia MESH:C000657245
26 833-848 Disease denotes Virus infection MESH:D001102
27 969-977 Disease denotes COVID-19 MESH:C000657245

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T2 325-334 Phenotype denotes Pneumonia http://purl.obolibrary.org/obo/HP_0002090

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T3 0-125 Sentence denotes ShuFeng JieDu capsule (SFJDC), a traditional Chinese medicine, has been recommended for the treatment of COVID-19 infections.
T4 126-202 Sentence denotes However, the pharmacological mechanism of SFJDC still remains vague to date.
T5 203-284 Sentence denotes The active ingredients and their target genes of SFJDC were collected from TCMSP.
T6 285-341 Sentence denotes COVID-19 is a type of Novel Coronavirus Pneumonia (NCP).
T7 342-406 Sentence denotes NCP-related target genes were collected from GeneCards database.
T8 407-482 Sentence denotes The ingredients-targets network of SFJDC and PPI networks were constructed.
T9 483-565 Sentence denotes The candidate genes were screened by Venn diagram package for enrichment analysis.
T10 566-633 Sentence denotes The gene-pathway network was structured to obtain key target genes.
T11 634-742 Sentence denotes In total, 124 active ingredients, 120 target genes of SFJDC and 251 NCP-related target genes were collected.
T12 743-849 Sentence denotes The functional annotations cluster 1 of 23 candidate genes (CGs) were related to lung and Virus infection.
T13 850-918 Sentence denotes RELA, MAPK1, MAPK14, CASP3, CASP8 and IL6 were the key target genes.
T14 919-1153 Sentence denotes The results suggested that SFJDC cloud be treated COVID-19 by multi-compounds and multi-pathways, and this study showed that the mechanism of traditional Chinese medicine (TCM) in the treatment of disease from the overall perspective.