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PMC:7532482 / 1308-24609 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T5 1220-1226 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T6 1458-1462 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T7 2299-2307 Body_part denotes Capsules http://purl.org/sig/ont/fma/fma85272
T8 2350-2358 Body_part denotes Capsules http://purl.org/sig/ont/fma/fma85272
T9 2376-2383 Body_part denotes capsule http://purl.org/sig/ont/fma/fma85272
T10 2623-2627 Body_part denotes body http://purl.org/sig/ont/fma/fma256135
T11 3009-3016 Body_part denotes capsule http://purl.org/sig/ont/fma/fma85272
T12 3433-3456 Body_part denotes upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T13 6059-6064 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T14 6065-6070 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T15 6604-6611 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T16 7211-7218 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T17 7219-7226 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T18 7563-7567 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T19 8539-8546 Body_part denotes Protein http://purl.org/sig/ont/fma/fma67257
T20 8547-8554 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T21 9205-9209 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T22 9363-9370 Body_part denotes Genomes http://purl.org/sig/ont/fma/fma84116
T23 9896-9900 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T24 10045-10049 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T25 10139-10143 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T26 11358-11362 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T27 14050-14068 Body_part denotes lipopolysaccharide http://purl.org/sig/ont/fma/fma82785
T28 15139-15152 Body_part denotes Bronchiolitis http://purl.org/sig/ont/fma/fma76497
T29 15228-15241 Body_part denotes bronchiolitis http://purl.org/sig/ont/fma/fma76497
T30 15264-15268 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T31 15316-15320 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T32 15366-15370 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T33 15622-15626 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T34 16322-16345 Body_part denotes upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T35 16382-16388 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T36 18728-18746 Body_part denotes lipopolysaccharide http://purl.org/sig/ont/fma/fma82785
T37 18827-18835 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T38 18959-18968 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T39 19117-19121 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T40 19506-19510 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T41 19563-19567 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T42 19568-19572 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T43 19642-19651 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T44 19690-19698 Body_part denotes cytokine http://purl.org/sig/ont/fma/fma84050
T45 19882-19895 Body_part denotes Bronchiolitis http://purl.org/sig/ont/fma/fma76497
T46 19971-19984 Body_part denotes bronchiolitis http://purl.org/sig/ont/fma/fma76497
T47 19990-19994 Body_part denotes lung http://purl.org/sig/ont/fma/fma7195
T48 20041-20045 Body_part denotes Gene http://purl.org/sig/ont/fma/fma74402
T49 20181-20185 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T50 20515-20531 Body_part denotes epithelial cells http://purl.org/sig/ont/fma/fma66768
T51 20526-20531 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T52 20533-20558 Body_part denotes alveolar epithelial cells http://purl.org/sig/ont/fma/fma62499
T53 20553-20558 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T54 20569-20586 Body_part denotes endothelial cells http://purl.org/sig/ont/fma/fma66772
T55 20581-20586 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T56 20601-20612 Body_part denotes macrophages http://purl.org/sig/ont/fma/fma63261
T57 20731-20740 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T58 20745-20755 Body_part denotes chemokines http://purl.org/sig/ont/fma/fma241981
T59 20987-20996 Body_part denotes cytokines http://purl.org/sig/ont/fma/fma84050
T60 21248-21252 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T61 21537-21545 Body_part denotes cysteine http://purl.org/sig/ont/fma/fma82751
T62 21644-21652 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T63 21701-21709 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T64 21757-21762 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T65 21989-21995 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T66 22126-22134 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T67 23049-23053 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T4 2376-2383 Body_part denotes capsule http://purl.obolibrary.org/obo/UBERON_0003893
T5 3009-3016 Body_part denotes capsule http://purl.obolibrary.org/obo/UBERON_0003893
T6 3433-3456 Body_part denotes upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T7 3439-3456 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T8 6059-6078 Body_part denotes blood-brain barrier http://purl.obolibrary.org/obo/UBERON_0000120
T9 6059-6064 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T10 6065-6070 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T11 8142-8147 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542
T12 15264-15268 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T13 16322-16345 Body_part denotes upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T14 16328-16345 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T15 16382-16388 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T16 19506-19510 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T17 19568-19572 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048
T18 19990-19994 Body_part denotes lung http://purl.obolibrary.org/obo/UBERON_0002048

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T10 54-63 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T11 97-101 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T12 228-237 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T13 238-246 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T14 324-332 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T15 610-618 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T16 741-776 Disease denotes acute respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0006502
T17 747-776 Disease denotes respiratory distress syndrome http://purl.obolibrary.org/obo/MONDO_0009971
T18 778-782 Disease denotes ARDS http://purl.obolibrary.org/obo/MONDO_0006502
T19 878-886 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T20 1296-1306 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T21 1359-1365 Disease denotes plague http://purl.obolibrary.org/obo/MONDO_0019095
T22 1747-1756 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T23 1757-1766 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T24 2464-2472 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T25 2814-2822 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T26 2903-2911 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T27 3073-3082 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T28 3304-3306 Disease denotes RB http://purl.obolibrary.org/obo/MONDO_0008380
T29 3439-3466 Disease denotes respiratory tract infection http://purl.obolibrary.org/obo/MONDO_0024355
T30 3457-3466 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T31 3478-3487 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T32 3572-3580 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T33 3581-3594 Disease denotes infections in http://purl.obolibrary.org/obo/MONDO_0005550
T34 3633-3642 Disease denotes Pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T35 3653-3661 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T36 3747-3756 Disease denotes Pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T37 3767-3775 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T38 4468-4476 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T39 4670-4678 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T40 4741-4749 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T41 4963-4971 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T42 4973-4981 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T43 5013-5022 Disease denotes Pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T44 5415-5423 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T45 6842-6850 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T46 6882-6891 Disease denotes Pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T47 7158-7167 Disease denotes Pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T48 8598-8601 Disease denotes DIP http://purl.obolibrary.org/obo/MONDO_0009887
T49 9292-9294 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T51 10388-10390 Disease denotes RB http://purl.obolibrary.org/obo/MONDO_0008380
T52 11033-11035 Disease denotes RB http://purl.obolibrary.org/obo/MONDO_0008380
T53 13784-13786 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T55 13868-13870 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T57 14149-14151 Disease denotes BH http://purl.obolibrary.org/obo/MONDO_0010873
T58 14633-14647 Disease denotes Kaposi sarcoma http://purl.obolibrary.org/obo/MONDO_0005055
T59 14640-14647 Disease denotes sarcoma http://purl.obolibrary.org/obo/MONDO_0005089
T60 14659-14680 Disease denotes herpesvirus infection http://purl.obolibrary.org/obo/MONDO_0005794
T61 14671-14680 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T62 14742-14767 Disease denotes cytomegalovirus infection http://purl.obolibrary.org/obo/MONDO_0005132
T63 14758-14767 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T64 14797-14808 Disease denotes Hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T65 14797-14806 Disease denotes Hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T66 15131-15137 Disease denotes Asthma http://purl.obolibrary.org/obo/MONDO_0004979
T67 15139-15152 Disease denotes Bronchiolitis http://purl.obolibrary.org/obo/MONDO_0002465
T68 15188-15211 Disease denotes Infections, respiratory http://purl.obolibrary.org/obo/MONDO_0024355
T69 15228-15241 Disease denotes bronchiolitis http://purl.obolibrary.org/obo/MONDO_0002465
T70 15290-15305 Disease denotes Virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T71 15296-15305 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T72 16040-16048 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T73 16322-16356 Disease denotes upper respiratory tract infections http://purl.obolibrary.org/obo/MONDO_0024355
T74 16366-16375 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T75 16377-16388 Disease denotes sore throat http://purl.obolibrary.org/obo/MONDO_0002258
T76 16390-16395 Disease denotes mumps http://purl.obolibrary.org/obo/MONDO_0000989
T77 16482-16490 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T78 16860-16868 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T79 17498-17504 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T80 17733-17739 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T81 18023-18031 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T82 18632-18634 Disease denotes MF http://purl.obolibrary.org/obo/MONDO_0009691|http://purl.obolibrary.org/obo/MONDO_0020481
T84 18805-18807 Disease denotes BH http://purl.obolibrary.org/obo/MONDO_0010873
T85 18854-18862 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T86 18863-18873 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T87 19009-19017 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T88 19257-19272 Disease denotes viral infection http://purl.obolibrary.org/obo/MONDO_0005108
T89 19263-19272 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T90 19283-19297 Disease denotes Kaposi sarcoma http://purl.obolibrary.org/obo/MONDO_0005055
T91 19290-19297 Disease denotes sarcoma http://purl.obolibrary.org/obo/MONDO_0005089
T92 19309-19330 Disease denotes herpesvirus infection http://purl.obolibrary.org/obo/MONDO_0005794
T93 19321-19330 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T94 19338-19363 Disease denotes cytomegalovirus infection http://purl.obolibrary.org/obo/MONDO_0005132
T95 19354-19363 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T96 19365-19376 Disease denotes Hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T97 19365-19374 Disease denotes Hepatitis http://purl.obolibrary.org/obo/MONDO_0002251
T98 19378-19387 Disease denotes Influenza http://purl.obolibrary.org/obo/MONDO_0005812
T99 19391-19419 Disease denotes Epstein-Barr virus infection http://purl.obolibrary.org/obo/MONDO_0005111
T100 19404-19419 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T101 19410-19419 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T102 19427-19443 Disease denotes immunodeficiency http://purl.obolibrary.org/obo/MONDO_0021094
T103 19452-19461 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T104 19466-19473 Disease denotes Measles http://purl.obolibrary.org/obo/MONDO_0004619
T105 19506-19518 Disease denotes lung disease http://purl.obolibrary.org/obo/MONDO_0005275
T106 19529-19541 Disease denotes tuberculosis http://purl.obolibrary.org/obo/MONDO_0018076
T107 19543-19552 Disease denotes pertussis http://purl.obolibrary.org/obo/MONDO_0005077
T108 19557-19579 Disease denotes small cell lung cancer http://purl.obolibrary.org/obo/MONDO_0008433
T109 19568-19579 Disease denotes lung cancer http://purl.obolibrary.org/obo/MONDO_0008903
T110 19573-19579 Disease denotes cancer http://purl.obolibrary.org/obo/MONDO_0004992
T111 19663-19675 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T112 19874-19880 Disease denotes Asthma http://purl.obolibrary.org/obo/MONDO_0004979
T113 19882-19895 Disease denotes Bronchiolitis http://purl.obolibrary.org/obo/MONDO_0002465
T114 19931-19954 Disease denotes Infections, respiratory http://purl.obolibrary.org/obo/MONDO_0024355
T115 19971-19984 Disease denotes bronchiolitis http://purl.obolibrary.org/obo/MONDO_0002465
T116 20016-20031 Disease denotes Virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T117 20022-20031 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T118 20317-20364 Disease denotes Severe Acute Respiratory Syndrome-Coronavirus-2 http://purl.obolibrary.org/obo/MONDO_0100096
T119 20317-20350 Disease denotes Severe Acute Respiratory Syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T120 20366-20370 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T121 20378-20387 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T122 20410-20428 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T123 20419-20428 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T124 20471-20475 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T125 21040-21049 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T126 21053-21061 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T127 21322-21334 Disease denotes inflammation http://purl.obolibrary.org/obo/MONDO_0021166
T128 21485-21493 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T129 21494-21503 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T130 21735-21744 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T131 21768-21776 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T132 21972-21980 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T133 22192-22200 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T134 22341-22349 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T135 22441-22449 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T136 22565-22573 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T137 22626-22634 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T138 22744-22752 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T139 23131-23140 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T140 23230-23238 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T18 34-35 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T19 109-112 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T20 259-261 http://purl.obolibrary.org/obo/CLO_0053733 denotes 11
T21 284-285 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T22 494-497 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T23 1220-1226 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T24 1326-1331 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T25 1539-1542 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T26 1543-1544 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T27 1721-1722 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T28 1901-1902 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T29 2520-2521 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T30 2728-2730 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T31 2797-2799 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T32 2811-2813 http://purl.obolibrary.org/obo/CLO_0001407 denotes 52
T33 3028-3029 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 3092-3094 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T35 3224-3226 http://purl.obolibrary.org/obo/CLO_0003797 denotes HP
T36 3224-3226 http://purl.obolibrary.org/obo/PR_000008725 denotes HP
T37 3325-3328 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T38 3802-3804 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T39 3830-3831 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T40 3945-3951 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T41 4062-4071 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T42 4157-4163 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T43 4219-4224 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T44 4348-4353 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T45 4755-4761 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T46 4782-4787 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T47 4985-4986 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T48 5034-5040 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T49 5070-5075 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T50 5131-5136 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T51 5462-5468 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T52 5508-5514 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T53 5671-5672 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T54 5762-5767 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T55 6059-6064 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T56 6059-6064 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T57 6065-6070 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T58 6065-6070 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T59 6113-6119 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T60 6113-6119 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T61 6113-6119 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T62 6113-6119 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T63 6134-6140 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T64 6134-6140 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T65 6134-6140 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T66 6134-6140 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T67 6165-6167 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T68 6216-6219 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T69 6238-6244 http://purl.obolibrary.org/obo/CLO_0002172 denotes Caco-2
T70 6238-6244 http://purl.obolibrary.org/obo/CLO_0051943 denotes Caco-2
T71 6238-6244 http://purl.obolibrary.org/obo/CLO_0051958 denotes Caco-2
T72 6238-6244 http://purl.obolibrary.org/obo/CLO_0051960 denotes Caco-2
T73 6284-6290 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T74 6374-6379 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T75 6445-6450 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T76 6454-6460 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T77 6543-6544 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T78 6700-6706 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T79 6801-6806 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T80 6854-6855 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T81 6989-6990 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T82 7110-7115 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T83 7116-7121 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T84 7302-7307 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T85 7450-7456 http://purl.obolibrary.org/obo/CLO_0001658 denotes Active
T86 7563-7567 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T87 7919-7920 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T88 8099-8100 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T89 8418-8419 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T90 8481-8482 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T91 8652-8653 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T92 8860-8862 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T93 8936-8938 http://purl.obolibrary.org/obo/CLO_0002878 denotes EC
T94 9001-9006 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T95 9205-9209 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T96 9301-9320 http://purl.obolibrary.org/obo/GO_0005575 denotes cellular components
T97 9322-9324 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T98 9353-9358 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Genes
T99 9667-9670 http://purl.obolibrary.org/obo/CLO_0001547 denotes A P
T100 9896-9900 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T101 9997-10002 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T102 10045-10049 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T103 10095-10100 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T104 10139-10143 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T105 10175-10181 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T106 10255-10261 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T107 10352-10354 http://purl.obolibrary.org/obo/CLO_0003797 denotes HP
T108 10352-10354 http://purl.obolibrary.org/obo/PR_000008725 denotes HP
T109 10445-10451 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T110 10583-10588 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T111 10634-10639 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T112 10658-10664 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T113 10763-10768 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T114 10808-10811 http://purl.obolibrary.org/obo/CLO_0050884 denotes ten
T115 10908-10913 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T116 10926-10931 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T117 10970-10975 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T118 11021-11023 http://purl.obolibrary.org/obo/CLO_0003797 denotes HP
T119 11021-11023 http://purl.obolibrary.org/obo/PR_000008725 denotes HP
T120 11063-11065 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T121 11088-11093 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T122 11231-11232 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T123 11246-11251 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T124 11331-11336 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T125 11358-11362 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T126 11442-11447 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T127 11535-11540 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T128 11590-11595 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T129 11705-11710 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T130 11767-11769 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2A
T131 11814-11819 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T132 11899-11904 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T133 11997-12002 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T134 12278-12283 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T135 12297-12298 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T136 12425-12430 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T137 12504-12505 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T138 12542-12543 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T139 12583-12588 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T140 12640-12641 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T141 13091-13096 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T142 13098-13099 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T143 13126-13131 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T144 13282-13287 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T145 13314-13315 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T146 13382-13384 http://purl.obolibrary.org/obo/CLO_0001387 denotes 4C
T147 13391-13396 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T148 13466-13471 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T149 13472-13477 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T150 13492-13497 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T151 13528-13533 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T152 13594-13599 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T153 13780-13782 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T154 13858-13864 http://purl.obolibrary.org/obo/CLO_0002223 denotes CC, 39
T155 13858-13860 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T156 14112-14120 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T157 14127-14135 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T158 14542-14547 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T159 14691-14700 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T160 14736-14741 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T161 14775-14784 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T162 14807-14808 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T163 14989-14990 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T164 15139-15152 http://purl.obolibrary.org/obo/UBERON_0002186 denotes Bronchiolitis
T165 15182-15187 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T166 15222-15227 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T167 15228-15241 http://purl.obolibrary.org/obo/UBERON_0002186 denotes bronchiolitis
T168 15264-15268 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T169 15264-15268 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T170 15290-15295 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T171 15316-15320 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T172 15366-15370 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T173 15551-15556 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T174 15622-15626 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T175 15664-15669 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T176 15767-15772 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T177 15856-15857 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T178 15930-15933 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T179 16007-16010 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T180 16011-16012 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T181 16056-16059 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T182 16256-16258 http://purl.obolibrary.org/obo/CLO_0001302 denotes 34
T183 16269-16270 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T184 16432-16435 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T185 16491-16493 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T186 16559-16562 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T187 16754-16756 http://purl.obolibrary.org/obo/CLO_0001313 denotes 36
T188 16789-16795 http://purl.obolibrary.org/obo/CLO_0001658 denotes active
T189 17099-17104 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T190 17199-17204 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T191 17236-17237 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T192 17281-17286 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T193 17384-17385 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T194 17417-17420 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T195 17441-17449 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T196 17590-17598 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T197 17646-17650 http://purl.obolibrary.org/obo/CLO_0001627 denotes a, a
T198 17801-17802 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T199 18042-18043 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T200 18265-18270 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T201 18309-18314 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T202 18391-18392 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T203 18410-18415 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T204 18485-18490 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T205 18491-18496 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T206 18511-18516 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T207 18541-18546 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T208 18628-18630 http://purl.obolibrary.org/obo/GO_0005575 denotes CC
T209 18768-18776 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T210 18783-18791 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T211 18884-18885 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T212 18941-18942 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T213 18974-18983 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T214 19068-19069 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T215 19083-19086 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T216 19117-19121 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T217 19332-19337 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T218 19375-19376 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T219 19388-19389 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T220 19404-19409 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T221 19421-19426 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes Human
T222 19444-19449 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T223 19506-19510 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T224 19506-19510 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T225 19563-19567 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T226 19568-19572 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T227 19568-19572 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T228 19628-19638 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T229 19723-19732 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T230 19749-19758 http://purl.obolibrary.org/obo/SO_0000418 denotes signaling
T231 19882-19895 http://purl.obolibrary.org/obo/UBERON_0002186 denotes Bronchiolitis
T232 19925-19930 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T233 19965-19970 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T234 19971-19984 http://purl.obolibrary.org/obo/UBERON_0002186 denotes bronchiolitis
T235 19990-19994 http://purl.obolibrary.org/obo/UBERON_0002048 denotes lung
T236 19990-19994 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lung
T237 20016-20021 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T238 20041-20045 http://purl.obolibrary.org/obo/OGG_0000000002 denotes Gene
T239 20105-20110 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T240 20181-20185 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T241 20202-20207 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T242 20276-20281 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T243 20435-20436 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T244 20482-20487 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T245 20515-20525 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T246 20526-20531 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T247 20542-20552 http://purl.obolibrary.org/obo/CL_0000066 denotes epithelial
T248 20553-20558 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T249 20569-20586 http://purl.obolibrary.org/obo/CL_0000115 denotes endothelial cells
T250 20794-20796 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T251 20805-20807 http://purl.obolibrary.org/obo/CLO_0007074 denotes kB
T252 20805-20807 http://purl.obolibrary.org/obo/CLO_0051988 denotes kB
T253 20830-20831 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T254 20879-20888 http://purl.obolibrary.org/obo/CLO_0001658 denotes activator
T255 20894-20903 http://purl.obolibrary.org/obo/CLO_0001658 denotes activates
T256 21248-21252 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T257 21347-21357 http://purl.obolibrary.org/obo/CLO_0001658 denotes activating
T258 21525-21526 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T259 21614-21624 http://purl.obolibrary.org/obo/CLO_0001658 denotes activation
T260 21710-21712 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T261 21748-21751 http://purl.obolibrary.org/obo/CLO_0001230 denotes 293
T262 21748-21751 http://purl.obolibrary.org/obo/CLO_0037237 denotes 293
T263 21748-21751 http://purl.obolibrary.org/obo/CLO_0050903 denotes 293
T264 21748-21751 http://purl.obolibrary.org/obo/CLO_0054249 denotes 293
T265 21748-21751 http://purl.obolibrary.org/obo/CLO_0054250 denotes 293
T266 21748-21751 http://purl.obolibrary.org/obo/CLO_0054251 denotes 293
T267 21748-21751 http://purl.obolibrary.org/obo/CLO_0054252 denotes 293
T268 21757-21762 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T269 21777-21786 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T270 21898-21907 http://purl.obolibrary.org/obo/CLO_0001658 denotes activated
T271 21989-21995 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T272 22066-22067 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T273 22080-22089 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humanized
T274 22095-22100 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T275 22260-22262 http://purl.obolibrary.org/obo/CLO_0001382 denotes 48
T276 22267-22270 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T277 22909-22910 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T278 23036-23041 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T279 23049-23053 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T6 840-844 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T7 949-955 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T8 965-974 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T9 984-997 Chemical denotes antimicrobial http://purl.obolibrary.org/obo/CHEBI_33281
T10 1018-1026 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T11 1095-1101 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T12 1398-1406 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T13 1483-1491 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T14 1523-1531 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T15 1533-1536 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T16 1875-1883 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T17 1933-1941 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T18 2702-2710 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T19 2721-2726 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T20 2781-2789 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T21 2790-2795 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T22 2881-2889 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T23 3050-3058 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T24 3181-3183 Chemical denotes FF http://purl.obolibrary.org/obo/CHEBI_72723
T25 3202-3204 Chemical denotes IR http://purl.obolibrary.org/obo/CHEBI_74061
T26 3224-3226 Chemical denotes HP http://purl.obolibrary.org/obo/CHEBI_74055
T27 3249-3251 Chemical denotes PR http://purl.obolibrary.org/obo/CHEBI_73645
T28 3269-3271 Chemical denotes VH http://purl.obolibrary.org/obo/CHEBI_73700
T29 3329-3338 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T30 3359-3370 Chemical denotes antipyretic http://purl.obolibrary.org/obo/CHEBI_35493
T31 3522-3526 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T32 3975-3979 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T33 4198-4206 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T34 4408-4411 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T35 4415-4418 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T36 4502-4510 Chemical denotes solution http://purl.obolibrary.org/obo/CHEBI_75958
T37 4587-4592 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T38 5748-5753 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T39 5868-5872 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T40 6146-6150 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T41 6161-6163 Chemical denotes DL http://purl.obolibrary.org/obo/CHEBI_68596
T42 6228-6230 Chemical denotes DL http://purl.obolibrary.org/obo/CHEBI_68596
T43 6604-6611 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T44 7206-7209 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T46 7211-7218 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T47 7219-7226 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T48 7312-7315 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T50 7510-7512 Chemical denotes Co http://purl.obolibrary.org/obo/CHEBI_27638
T51 7579-7581 Chemical denotes Co http://purl.obolibrary.org/obo/CHEBI_27638
T52 7651-7654 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T54 7689-7692 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T56 8317-8320 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T58 8420-8423 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T60 8539-8546 Chemical denotes Protein http://purl.obolibrary.org/obo/CHEBI_16541
T61 8547-8554 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T62 8860-8862 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T63 8906-8909 Chemical denotes LAC http://purl.obolibrary.org/obo/CHEBI_90184
T64 9266-9268 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T65 9292-9294 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T66 9322-9324 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T67 10333-10335 Chemical denotes FF http://purl.obolibrary.org/obo/CHEBI_72723
T68 10343-10345 Chemical denotes IR http://purl.obolibrary.org/obo/CHEBI_74061
T69 10352-10354 Chemical denotes HP http://purl.obolibrary.org/obo/CHEBI_74055
T70 10361-10363 Chemical denotes PR http://purl.obolibrary.org/obo/CHEBI_73645
T71 10370-10372 Chemical denotes VH http://purl.obolibrary.org/obo/CHEBI_73700
T72 11000-11002 Chemical denotes PR http://purl.obolibrary.org/obo/CHEBI_73645
T73 11011-11013 Chemical denotes IR http://purl.obolibrary.org/obo/CHEBI_74061
T74 11021-11023 Chemical denotes HP http://purl.obolibrary.org/obo/CHEBI_74055
T75 11056-11058 Chemical denotes FF http://purl.obolibrary.org/obo/CHEBI_72723
T76 11389-11392 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T78 11482-11485 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T80 11786-11789 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T82 11905-11908 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T84 12482-12489 Chemical denotes Wogonin http://purl.obolibrary.org/obo/CHEBI_10043
T85 12510-12518 Chemical denotes acacetin http://purl.obolibrary.org/obo/CHEBI_57284
T86 12520-12527 Chemical denotes Wogonin http://purl.obolibrary.org/obo/CHEBI_10043
T87 12548-12556 Chemical denotes acacetin http://purl.obolibrary.org/obo/CHEBI_57284
T88 12618-12625 Chemical denotes Wogonin http://purl.obolibrary.org/obo/CHEBI_10043
T89 12646-12654 Chemical denotes acacetin http://purl.obolibrary.org/obo/CHEBI_57284
T90 12785-12788 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T92 12827-12830 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T94 13776-13778 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T95 13780-13782 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T96 13784-13786 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T97 13848-13850 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T98 13858-13860 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T99 13868-13870 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T100 14050-14068 Chemical denotes lipopolysaccharide http://purl.obolibrary.org/obo/CHEBI_16412
T101 14082-14090 Chemical denotes molecule http://purl.obolibrary.org/obo/CHEBI_25367
T102 14682-14685 Chemical denotes AGE http://purl.obolibrary.org/obo/CHEBI_84123
T103 14769-14771 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T105 15875-15879 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T106 15926-15929 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T107 16003-16006 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T108 16199-16207 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T109 16291-16299 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T110 16456-16460 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T111 16536-16544 Chemical denotes medicine http://purl.obolibrary.org/obo/CHEBI_23888
T112 17214-17221 Chemical denotes Wogonin http://purl.obolibrary.org/obo/CHEBI_10043
T113 17242-17250 Chemical denotes acacetin http://purl.obolibrary.org/obo/CHEBI_57284
T114 17375-17382 Chemical denotes Wogonin http://purl.obolibrary.org/obo/CHEBI_10043
T115 17406-17415 Chemical denotes flavonoid http://purl.obolibrary.org/obo/CHEBI_47916|http://purl.obolibrary.org/obo/CHEBI_72544
T117 17560-17567 Chemical denotes wogonin http://purl.obolibrary.org/obo/CHEBI_10043|http://purl.obolibrary.org/obo/CHEBI_78338
T119 17651-17660 Chemical denotes flavonoid http://purl.obolibrary.org/obo/CHEBI_47916|http://purl.obolibrary.org/obo/CHEBI_72544
T121 17791-17799 Chemical denotes Acacetin http://purl.obolibrary.org/obo/CHEBI_15335
T122 17801-17810 Chemical denotes a flavone http://purl.obolibrary.org/obo/CHEBI_24043
T123 17803-17810 Chemical denotes flavone http://purl.obolibrary.org/obo/CHEBI_42491
T124 17928-17936 Chemical denotes acacetin http://purl.obolibrary.org/obo/CHEBI_57284
T125 17951-17953 Chemical denotes PR http://purl.obolibrary.org/obo/CHEBI_73645
T126 17955-17957 Chemical denotes IR http://purl.obolibrary.org/obo/CHEBI_74061
T127 18160-18163 Chemical denotes PPI http://purl.obolibrary.org/obo/CHEBI_53266|http://purl.obolibrary.org/obo/CHEBI_60614
T129 18624-18626 Chemical denotes BP http://purl.obolibrary.org/obo/CHEBI_29865
T130 18628-18630 Chemical denotes CC http://purl.obolibrary.org/obo/CHEBI_28940
T131 18632-18634 Chemical denotes MF http://purl.obolibrary.org/obo/CHEBI_74708
T132 18728-18746 Chemical denotes lipopolysaccharide http://purl.obolibrary.org/obo/CHEBI_16412
T133 19070-19073 Chemical denotes TCM http://purl.obolibrary.org/obo/CHEBI_145500
T134 19717-19719 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T136 20635-20646 Chemical denotes Angiotensin http://purl.obolibrary.org/obo/CHEBI_2719
T137 20767-20769 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T139 20778-20780 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T141 20802-20804 Chemical denotes NF http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224
T144 21388-21403 Chemical denotes MAPK inhibitors http://purl.obolibrary.org/obo/CHEBI_79091
T145 21393-21403 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T146 21537-21545 Chemical denotes cysteine http://purl.obolibrary.org/obo/CHEBI_15356
T147 21644-21652 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T148 21701-21709 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T149 22005-22007 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T151 22101-22103 Chemical denotes IL http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072
T153 22887-22894 Chemical denotes Wogonin http://purl.obolibrary.org/obo/CHEBI_10043
T154 22915-22923 Chemical denotes acacetin http://purl.obolibrary.org/obo/CHEBI_57284

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
35 80-95 Species denotes new coronavirus Tax:2697049
36 97-107 Species denotes SARS-COV-2 Tax:2697049
37 36-63 Disease denotes novel coronavirus pneumonia MESH:C000657245
38 210-237 Disease denotes novel coronavirus pneumonia MESH:C000657245
39 238-246 Disease denotes COVID-19 MESH:C000657245
40 324-332 Disease denotes COVID-19 MESH:C000657245
41 354-360 Disease denotes deaths MESH:D003643
54 602-608 Species denotes people Tax:9606
55 624-632 Species denotes patients Tax:9606
56 707-715 Species denotes patients Tax:9606
57 427-438 Species denotes respiratory Tax:12814
58 610-618 Disease denotes COVID-19 MESH:C000657245
59 646-651 Disease denotes fever MESH:D005334
60 653-660 Disease denotes fatigue MESH:D005221
61 662-671 Disease denotes dry cough MESH:D003371
62 732-739 Disease denotes dyspnea MESH:D004417
63 741-776 Disease denotes acute respiratory distress syndrome MESH:D012128
64 778-782 Disease denotes ARDS MESH:D012128
65 787-799 Disease denotes septic shock MESH:D012772
83 1210-1218 Species denotes patients Tax:9606
84 1252-1260 Species denotes patients Tax:9606
85 2473-2481 Species denotes patients Tax:9606
86 2823-2831 Species denotes patients Tax:9606
87 2944-2951 Species denotes patient Tax:9606
88 1058-1069 Species denotes respiratory Tax:12814
89 949-955 Chemical denotes oxygen MESH:D010100
90 1095-1101 Chemical denotes oxygen MESH:D010100
91 878-886 Disease denotes COVID-19 MESH:C000657245
92 1195-1209 Disease denotes critically ill MESH:D016638
93 1296-1315 Disease denotes infectious diseases MESH:D003141
94 1735-1766 Disease denotes coronavirus infection pneumonia MESH:D018352
95 2262-2280 Disease denotes QingFei PaiDu Tang MESH:C536897
96 2464-2472 Disease denotes COVID-19 MESH:C000657245
97 2814-2822 Disease denotes COVID-19 MESH:C000657245
98 2840-2858 Disease denotes QingFei PaiDu Tang MESH:C536897
99 2903-2911 Disease denotes COVID-19 MESH:C000657245
111 3202-3204 Gene denotes IR Gene:3643
112 3249-3251 Gene denotes PR Gene:140738
113 3229-3247 Disease denotes Phragmitis Rhizoma
114 3433-3466 Disease denotes upper respiratory tract infection MESH:D012141
115 3468-3487 Disease denotes pulmonary infection MESH:D012141
116 3572-3580 Disease denotes COVID-19 MESH:C000657245
117 3581-3591 Disease denotes infections MESH:D007239
118 3633-3642 Disease denotes Pneumonia MESH:D011014
119 3653-3661 Disease denotes COVID-19 MESH:C000657245
120 3747-3756 Disease denotes Pneumonia MESH:D011014
121 3767-3775 Disease denotes COVID-19 MESH:C000657245
126 4468-4476 Disease denotes COVID-19 MESH:C000657245
127 4631-4649 Disease denotes QingFei PaiDu Tang MESH:C536897
128 4670-4678 Disease denotes COVID-19 MESH:C000657245
129 4741-4749 Disease denotes COVID-19 MESH:C000657245
134 4963-4971 Disease denotes COVID-19 MESH:C000657245
135 4973-4981 Disease denotes COVID-19 MESH:C000657245
136 4995-5022 Disease denotes Novel Coronavirus Pneumonia MESH:C000657245
137 5415-5423 Disease denotes COVID-19 MESH:C000657245
142 6220-6222 Gene denotes OB Gene:1009
143 6108-6110 Gene denotes OB Gene:1009
144 5890-5894 Chemical denotes ADME
145 6238-6244 Chemical denotes Caco-2
147 6822-6825 Gene denotes NCP
152 7110-7115 Species denotes human Tax:9606
153 6842-6850 Disease denotes COVID-19 MESH:C000657245
154 6864-6891 Disease denotes Novel Coronavirus Pneumonia MESH:C000657245
155 7140-7167 Disease denotes Novel Coronavirus Pneumonia MESH:C000657245
157 7847-7852 Gene denotes SFJDC
159 8019-8029 Species denotes Strawberry Tax:3747
162 8626-8630 Gene denotes MINT Gene:23013
163 8936-8938 Disease denotes EC MESH:D005955
166 10343-10345 Gene denotes IR Gene:3643
167 10361-10363 Gene denotes PR Gene:140738
170 11011-11013 Gene denotes IR Gene:3643
171 11000-11002 Gene denotes PR Gene:140738
173 12029-12034 Gene denotes SFJDC
184 12612-12614 Gene denotes OB Gene:1009
185 12482-12489 Chemical denotes Wogonin MESH:C085514
186 12491-12505 Chemical denotes licochalcone a MESH:C070840
187 12510-12518 Chemical denotes acacetin MESH:C023717
188 12520-12527 Chemical denotes Wogonin MESH:C085514
189 12529-12543 Chemical denotes licochalcone a MESH:C070840
190 12548-12556 Chemical denotes acacetin MESH:C023717
191 12618-12625 Chemical denotes Wogonin MESH:C085514
192 12627-12641 Chemical denotes licochalcone a MESH:C070840
193 12646-12654 Chemical denotes acacetin MESH:C023717
195 13466-13471 Species denotes human Tax:9606
198 14050-14068 Chemical denotes lipopolysaccharide MESH:D008070
199 14171-14176 Disease denotes death MESH:D003643
207 14682-14685 Gene denotes AGE Gene:5973
208 14686-14690 Gene denotes RAGE Gene:177
209 14769-14774 Gene denotes IL-17 Gene:3605
210 14633-14680 Disease denotes Kaposi sarcoma-associated herpesvirus infection MESH:D012514
211 14712-14734 Disease denotes diabetic complications MESH:D048909
212 14742-14767 Disease denotes cytomegalovirus infection MESH:D003586
213 14797-14808 Disease denotes Hepatitis B MESH:D006509
217 15139-15198 Disease denotes Bronchiolitis Viral, Respiratory Syncytial Virus Infections
218 15200-15241 Disease denotes respiratory syncytial virus bronchiolitis
219 15290-15313 Disease denotes Virus infection disease MESH:D001102
226 15597-15601 Gene denotes RELA Gene:5970
227 15701-15706 Gene denotes MAPK1 Gene:5594
228 15708-15714 Gene denotes MAPK14 Gene:1432
229 15716-15721 Gene denotes CASP3 Gene:836
230 15723-15728 Gene denotes CASP8 Gene:841
231 15733-15736 Gene denotes IL6 Gene:3569
237 16040-16048 Disease denotes COVID-19 MESH:C000657245
238 16322-16356 Disease denotes upper respiratory tract infections MESH:D012141
239 16377-16388 Disease denotes sore throat MESH:D010608
240 16482-16490 Disease denotes COVID-19 MESH:C000657245
241 16860-16868 Disease denotes COVID-19 MESH:C000657245
255 17616-17620 Gene denotes AMPK Gene:5562
256 17214-17221 Chemical denotes Wogonin MESH:C085514
257 17223-17237 Chemical denotes licochalcone a MESH:C070840
258 17242-17250 Chemical denotes acacetin MESH:C023717
259 17375-17382 Chemical denotes Wogonin MESH:C085514
260 17406-17415 Chemical denotes flavonoid MESH:D005419
261 17633-17647 Chemical denotes Licochalcone a MESH:C070840
262 17651-17660 Chemical denotes flavonoid MESH:D005419
263 17791-17799 Chemical denotes Acacetin MESH:C023717
264 17803-17810 Chemical denotes flavone MESH:C043562
265 17483-17491 Disease denotes fibrosis MESH:D005355
266 17498-17504 Disease denotes cancer MESH:D009369
267 17733-17739 Disease denotes cancer MESH:D009369
273 17955-17957 Gene denotes IR Gene:3643
274 17921-17923 Gene denotes OB Gene:1009
275 17951-17953 Gene denotes PR Gene:140738
276 17928-17936 Chemical denotes acacetin MESH:C023717
277 18023-18031 Disease denotes COVID-19 MESH:C000657245
279 18485-18490 Species denotes human Tax:9606
284 18728-18746 Chemical denotes lipopolysaccharide MESH:D008070
285 18854-18862 Disease denotes COVID-19 MESH:C000657245
286 18863-18873 Disease denotes infections MESH:D007239
287 19009-19017 Disease denotes COVID-19 MESH:C000657245
303 19717-19722 Gene denotes IL-17 Gene:3605
304 19745-19748 Gene denotes TNF Gene:7124
305 19257-19272 Disease denotes viral infection MESH:D001102
306 19283-19330 Disease denotes Kaposi sarcoma-associated herpesvirus infection MESH:D012514
307 19338-19363 Disease denotes cytomegalovirus infection MESH:D003586
308 19365-19376 Disease denotes Hepatitis B MESH:D006509
309 19391-19419 Disease denotes Epstein-Barr virus infection MESH:D020031
310 19427-19461 Disease denotes immunodeficiency virus 1 infection MESH:D001102
311 19506-19518 Disease denotes lung disease MESH:D008171
312 19529-19541 Disease denotes tuberculosis MESH:D014376
313 19557-19579 Disease denotes small cell lung cancer MESH:D055752
314 19663-19675 Disease denotes inflammation MESH:D007249
315 19882-19941 Disease denotes Bronchiolitis Viral, Respiratory Syncytial Virus Infections
316 19943-19984 Disease denotes respiratory syncytial virus bronchiolitis
317 20016-20039 Disease denotes Virus infection disease MESH:D001102
365 20136-20140 Gene denotes RELA Gene:5970
366 20216-20221 Gene denotes MAPK1 Gene:5594
367 20223-20229 Gene denotes MAPK14 Gene:1432
368 20231-20236 Gene denotes CASP3 Gene:836
369 20238-20243 Gene denotes CASP8 Gene:841
370 20248-20251 Gene denotes IL6 Gene:3569
371 20635-20666 Gene denotes Angiotensin converting enzyme 2 Gene:59272
372 20668-20672 Gene denotes ACE2 Gene:59272
373 20767-20771 Gene denotes IL-6 Gene:3569
374 20773-20776 Gene denotes TNF Gene:7124
375 20778-20783 Gene denotes IL-10 Gene:3586
376 20788-20792 Gene denotes MCP1 Gene:6347
377 20822-20826 Gene denotes RELA Gene:5970
378 21001-21005 Gene denotes RELA Gene:5970
379 21063-21068 Gene denotes MAPK1 Gene:5594
380 21073-21079 Gene denotes MAPK14 Gene:1432
381 21508-21513 Gene denotes CASP3 Gene:836
382 21518-21523 Gene denotes CASP8 Gene:841
383 21824-21832 Gene denotes caspase3 Gene:836
384 21834-21843 Gene denotes caspase 8 Gene:841
385 21875-21880 Gene denotes CASP3 Gene:836
386 21885-21890 Gene denotes CASP8 Gene:841
387 22005-22009 Gene denotes IL-6 Gene:3569
388 20317-20364 Species denotes Severe Acute Respiratory Syndrome-Coronavirus-2 Tax:2697049
389 20366-20376 Species denotes SARS-COV-2 Tax:2697049
390 20471-20481 Species denotes SARS-COV-2 Tax:2697049
391 21296-21301 Species denotes CoV-2 Tax:2697049
392 21768-21776 Species denotes SARS-CoV Tax:694009
393 22027-22035 Species denotes patients Tax:9606
394 22201-22209 Species denotes patients Tax:9606
395 20503-20514 Species denotes respiratory Tax:12814
396 22095-22100 Species denotes human Tax:9606
397 22053-22064 Chemical denotes Tocilizumab MESH:C502936
398 20378-20387 Disease denotes infection MESH:D007239
399 20410-20428 Disease denotes SARS-CoV infection MESH:C000657245
400 21040-21049 Disease denotes infection MESH:D007239
401 21053-21061 Disease denotes COVID-19 MESH:C000657245
402 21271-21277 Disease denotes Joseph MESH:D017827
403 21322-21334 Disease denotes inflammation MESH:D007249
404 21485-21493 Disease denotes COVID-19 MESH:C000657245
405 21494-21503 Disease denotes infection MESH:D007239
406 21735-21744 Disease denotes infection MESH:D007239
407 21972-21980 Disease denotes COVID-19 MESH:C000657245
408 22041-22049 Disease denotes COVID-19 MESH:C000657245
409 22192-22200 Disease denotes COVID-19 MESH:C000657245
410 22250-22259 Disease denotes mortality MESH:D003643
411 21748-21756 CellLine denotes 293/ACE2 CVCL:L310
421 22450-22458 Species denotes patients Tax:9606
422 22574-22582 Species denotes patients Tax:9606
423 22614-22621 Chemical denotes Arbidol MESH:C086979
424 22662-22669 Chemical denotes Arbidol MESH:C086979
425 22341-22349 Disease denotes COVID-19 MESH:C000657245
426 22441-22449 Disease denotes COVID-19 MESH:C000657245
427 22565-22573 Disease denotes COVID-19 MESH:C000657245
428 22626-22634 Disease denotes COVID-19 MESH:C000657245
429 22744-22752 Disease denotes COVID-19 MESH:C000657245
441 22972-22976 Gene denotes RELA Gene:5970
442 22978-22983 Gene denotes MAPK1 Gene:5594
443 22985-22991 Gene denotes MAPK14 Gene:1432
444 22993-22998 Gene denotes CASP3 Gene:836
445 23000-23005 Gene denotes CASP8 Gene:841
446 23010-23013 Gene denotes IL6 Gene:3569
447 22887-22894 Chemical denotes Wogonin MESH:C085514
448 22896-22910 Chemical denotes licochalcone a MESH:C070840
449 22915-22923 Chemical denotes acacetin MESH:C023717
450 23113-23140 Disease denotes novel coronavirus pneumonia MESH:C000657245
451 23230-23238 Disease denotes COVID-19 MESH:C000657245
461 9008-9010 Chemical denotes CG
471 6400-6405 Chemical denotes TCMSP

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T3 54-63 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T4 228-237 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T5 646-651 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T6 653-660 Phenotype denotes fatigue http://purl.obolibrary.org/obo/HP_0012378
T7 662-671 Phenotype denotes dry cough http://purl.obolibrary.org/obo/HP_0031246
T8 732-739 Phenotype denotes dyspnea http://purl.obolibrary.org/obo/HP_0002094
T9 747-767 Phenotype denotes respiratory distress http://purl.obolibrary.org/obo/HP_0002098
T10 794-799 Phenotype denotes shock http://purl.obolibrary.org/obo/HP_0031273
T11 1757-1766 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T12 3433-3466 Phenotype denotes upper respiratory tract infection http://purl.obolibrary.org/obo/HP_0002788
T13 3468-3487 Phenotype denotes pulmonary infection http://purl.obolibrary.org/obo/HP_0006532
T14 3633-3642 Phenotype denotes Pneumonia http://purl.obolibrary.org/obo/HP_0002090
T15 3747-3756 Phenotype denotes Pneumonia http://purl.obolibrary.org/obo/HP_0002090
T16 5013-5022 Phenotype denotes Pneumonia http://purl.obolibrary.org/obo/HP_0002090
T17 6882-6891 Phenotype denotes Pneumonia http://purl.obolibrary.org/obo/HP_0002090
T18 7158-7167 Phenotype denotes Pneumonia http://purl.obolibrary.org/obo/HP_0002090
T19 14633-14647 Phenotype denotes Kaposi sarcoma http://purl.obolibrary.org/obo/HP_0100726
T20 14797-14806 Phenotype denotes Hepatitis http://purl.obolibrary.org/obo/HP_0012115
T21 15131-15137 Phenotype denotes Asthma http://purl.obolibrary.org/obo/HP_0002099
T22 15139-15152 Phenotype denotes Bronchiolitis http://purl.obolibrary.org/obo/HP_0011950
T23 15228-15241 Phenotype denotes bronchiolitis http://purl.obolibrary.org/obo/HP_0011950
T24 16322-16356 Phenotype denotes upper respiratory tract infections http://purl.obolibrary.org/obo/HP_0002788
T25 16377-16388 Phenotype denotes sore throat http://purl.obolibrary.org/obo/HP_0033050
T26 17498-17504 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T27 17733-17739 Phenotype denotes cancer http://purl.obolibrary.org/obo/HP_0002664
T28 19283-19297 Phenotype denotes Kaposi sarcoma http://purl.obolibrary.org/obo/HP_0100726
T29 19365-19374 Phenotype denotes Hepatitis http://purl.obolibrary.org/obo/HP_0012115
T30 19427-19443 Phenotype denotes immunodeficiency http://purl.obolibrary.org/obo/HP_0002721
T31 19506-19518 Phenotype denotes lung disease http://purl.obolibrary.org/obo/HP_0002088
T32 19557-19579 Phenotype denotes small cell lung cancer http://purl.obolibrary.org/obo/HP_0030357
T33 19874-19880 Phenotype denotes Asthma http://purl.obolibrary.org/obo/HP_0002099
T34 19882-19895 Phenotype denotes Bronchiolitis http://purl.obolibrary.org/obo/HP_0011950
T35 19971-19984 Phenotype denotes bronchiolitis http://purl.obolibrary.org/obo/HP_0011950
T36 21180-21196 Phenotype denotes oxidative stress http://purl.obolibrary.org/obo/HP_0025464
T37 23131-23140 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 4048-4080 http://purl.obolibrary.org/obo/GO_0009966 denotes regulation of signaling pathways
T2 4048-4071 http://purl.obolibrary.org/obo/GO_0023051 denotes regulation of signaling
T3 4048-4058 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T4 4062-4071 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T5 4089-4099 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T6 5962-5972 http://purl.obolibrary.org/obo/GO_0008152 denotes metabolism
T7 5977-5986 http://purl.obolibrary.org/obo/GO_0007588 denotes excretion
T8 10714-10721 http://purl.obolibrary.org/obo/GO_0015292 denotes Uniport
T9 14038-14068 http://purl.obolibrary.org/obo/GO_0032496 denotes response to lipopolysaccharide
T10 14070-14110 http://purl.obolibrary.org/obo/GO_0002237 denotes response to molecule of bacterial origin
T11 14691-14708 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T12 14691-14700 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T13 14775-14792 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T14 14775-14784 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T15 17616-17620 http://purl.obolibrary.org/obo/GO_0050405 denotes AMPK
T16 17616-17620 http://purl.obolibrary.org/obo/GO_0047322 denotes AMPK
T17 17616-17620 http://purl.obolibrary.org/obo/GO_0004691 denotes AMPK
T18 18716-18746 http://purl.obolibrary.org/obo/GO_0032496 denotes response to lipopolysaccharide
T19 18893-18908 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T20 19257-19272 http://purl.obolibrary.org/obo/GO_0016032 denotes viral infection
T21 19663-19675 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T22 19723-19740 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T23 19723-19732 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T24 19749-19766 http://purl.obolibrary.org/obo/GO_0007165 denotes signaling pathway
T25 19749-19758 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T26 20444-20465 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammatory response
T27 20863-20878 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T28 21099-21103 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T29 21140-21158 http://purl.obolibrary.org/obo/GO_0009987 denotes cellular processes
T30 21168-21196 http://purl.obolibrary.org/obo/GO_0006979 denotes response to oxidative stress
T31 21217-21232 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response
T32 21234-21243 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T33 21234-21243 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T34 21248-21266 http://purl.obolibrary.org/obo/GO_0008283 denotes cell proliferation
T35 21322-21334 http://purl.obolibrary.org/obo/GO_0006954 denotes inflammation
T36 21362-21366 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T37 21388-21392 http://purl.obolibrary.org/obo/GO_0004707 denotes MAPK
T38 21665-21676 http://purl.obolibrary.org/obo/GO_0006508 denotes proteolysis
T39 21777-21796 http://purl.obolibrary.org/obo/GO_0043065 denotes activated apoptosis
T40 21787-21796 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T41 21787-21796 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T15 0-12 Sentence denotes Introduction
T16 13-194 Sentence denotes Since December 2019, a novel coronavirus pneumonia (NCP) caused by new coronavirus (SARS-COV-2) has been prevalent in China and other countries, such as United States and Korea 1-3.
T17 195-385 Sentence denotes WHO named this novel coronavirus pneumonia COVID-19 on February 11, 2020 4 and there was a total of 20 million reported cases of COVID-19 globally and 750,000 deaths as of August 10, 2020 5.
T18 386-609 Sentence denotes Its transmission route is mainly through respiratory droplets, but also through contact transmission, which has the characteristics of rapid spread, strong infectivity and general susceptibility of various groups of people.
T19 610-819 Sentence denotes COVID-19 mild patients present with fever, fatigue, dry cough and other symptoms, whereas severe patients can appear with dyspnea, acute respiratory distress syndrome (ARDS) or septic shock and other symptoms.
T20 820-860 Sentence denotes There is no special drug at present 6,7.
T21 861-1037 Sentence denotes The treatment of COVID-19 mainly consisted of bed rest; intensive supportive treatment; oxygen therapy; antiviral therapy; antimicrobial therapy and Chinese medicine treatment.
T22 1038-1283 Sentence denotes Critical cases need respiratory support (high flow nasal oxygen therapy, non-invasive ventilator or invasive mechanical ventilator); circulatory support for critically ill patients; plasma treatment from recovered patients and immunotherapy 8,9.
T23 1284-1466 Sentence denotes Most of the infectious diseases caused by virus belong to the category of "plague" in ancient Chinese traditional medicine, which is caused by many evil spirits invading the body 10.
T24 1467-1581 Sentence denotes The traditional medicine, including traditional Chinese medicine (TCM), has a good therapeutic effect on it 11,12.
T25 1582-1987 Sentence denotes The Health and Health Commission of China and the State Administration of traditional Chinese Medicine in the "circular on the issuance of a new type of coronavirus infection pneumonia diagnosis and treatment program (version 5)" requested to strengthen the integration of Chinese and western medicine, and recommended a number of proprietary Chinese medicine in the process of diagnosis and treatment 13.
T26 1988-2203 Sentence denotes On the basis of the national plan and in accordance with the principle of "three conditions and conditions", local prevention and control projects have also been successively issued according to local conditions 14.
T27 2204-2386 Sentence denotes Recommended Chinese medicines include MaXing ShiGan Tang, QingFei PaiDu Tang, HuoXiang ZhengQi Capsules, JinHua QingGan Granules, LianHua QingWen Capsules or ShuFeng JieDu capsule 8.
T28 2387-2519 Sentence denotes One clinical study showed that LianHua QingWen could improve the symptoms of COVID-19 patients and shorten the course of disease 15.
T29 2520-2994 Sentence denotes A retrospective analysis study showed that the time of disappearance of clinical symptoms, recovery of body temperature, average length of stay in the integrated Chinese and western medicine treatment group (34) was significantly lower than that of the western medicine group (18) among the 52 COVID-19 patients 16.With QingFei PaiDu Tang combined with western medicine to treat the COVID-19 could significantly improve the patient's symptoms and achieved better results 17.
T30 2995-3095 Sentence denotes ShuFeng JieDu capsule (SFJDC) is a traditional Chinese medicine used to treat influenza in China 18.
T31 3096-3318 Sentence denotes SFJDC is composed of Polygoni Cuspidati Rhizoma Et Radix (PCRR), Forsythiae Fructus (FF), Isatidis Radix (IR), Herba Patriniae (HP), Phragmitis Rhizoma (PR), Verbenae Herb (VH), licorice (I), Radix Bupleuri (RB) (Table 1).
T32 3319-3404 Sentence denotes SFJDC has antiviral, anti-inflammatory, antipyretic and immune regulatory effects 19.
T33 3405-3680 Sentence denotes SFJDC was commonly used for upper respiratory tract infection, pulmonary infection, AECOPD and other disease 20.This drug now is also recommended for the treatment of COVID-19 infections in the latest Diagnosis and Treatment of Pneumonia Caused by COVID-19 (version 5) 13,21.
T34 3681-3805 Sentence denotes Currently, SFJDC is recommended in the Diagnosis and Treatment of Pneumonia Caused by COVID-19 in 5 provinces and cities 22.
T35 3806-3997 Sentence denotes Network pharmacology is a new discipline based on the theory of system biology, which analyzes the biological systems and selects specific signal nodes for multi-target drug molecular design.
T36 3998-4266 Sentence denotes Network pharmacology emphasizes the multi-pathway regulation of signaling pathways and the regulation of multi-component, multi-target, multi-pathway, linking active components in traditional chinese medicine with target genes from molecular and biological aspects 23.
T37 4267-4429 Sentence denotes Network pharmacology will help to understand the relationship among ingredients, genes and diseases and is suitable for the study of complex TCM or TCM compounds.
T38 4430-4573 Sentence denotes The potential mechanism of preventing COVID-19 by HuoXiang ZhengQi oral solution was realized by network pharmacology and molecular docking 24.
T39 4574-4709 Sentence denotes The research group Jing Zhao elucidated the mechanism of QingFei PaiDu Tang in the treatment of COVID-19 using network pharmacology 25.
T40 4710-4825 Sentence denotes SFJDC could be efficacious for COVID-19, but active incredients, target genes and putative mechanism are not known.
T41 4826-4972 Sentence denotes In the present study, the network pharmacological was used to investigate the possible mechanism and target of SFJDC in the treatment of COVID-19.
T42 4973-5029 Sentence denotes COVID-19 is a type of Novel Coronavirus Pneumonia (NCP).
T43 5030-5111 Sentence denotes The active ingredients and their target genes of SFJDC were collected from TCMSP.
T44 5112-5176 Sentence denotes NCP-related target genes were collected from GeneCards database.
T45 5177-5258 Sentence denotes The putative mechanism of SFJDC against NCP were analyzed by GO and KEGG pathway.
T46 5259-5319 Sentence denotes The flowchart of network pharmacology was shown in Figure 1.
T47 5320-5424 Sentence denotes The study provided possible theoretical reference for SFJDC in the prevention and treatment of COVID-19.
T48 5426-5447 Sentence denotes Materials and Methods
T49 5449-5489 Sentence denotes Screening of active Ingredients in SFJDC
T50 5490-5661 Sentence denotes We identified the active ingredients of SFJDC from Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP http://tcmspw.com/tcmsp.php) 26.
T51 5662-5781 Sentence denotes TCMSP is a unique herbal pharmacology platform that captures the relationship between drugs, target genes and diseases.
T52 5782-5889 Sentence denotes The database includes the detection of natural compounds such as chemical, target and drug target networks.
T53 5890-6021 Sentence denotes ADME is pharmacokinetics, which refers to the absorption, distribution, metabolism and excretion of exogenous chemicals by myosome.
T54 6022-6168 Sentence denotes The four key parameters of ADME were blood-brain barrier (BBB), oral bioavailability (OB), Caco-2 permeability (Caco-2) and drug-likeness (DL) 27.
T55 6169-6332 Sentence denotes In this study select candidate compounds which has OB≥30%, DL≥ 0.18, Caco-2≥-0.4, BBB≥-0.3.Then we sorted out each active ingredient for identification of targets.
T56 6334-6379 Sentence denotes Identification of SFJDC putative target genes
T57 6380-6482 Sentence denotes This study used the TCMSP platform to obtain the putative target genes of active ingredients of SFJDC.
T58 6483-6646 Sentence denotes The Uniprot (https://www.uniprot.org/) 28 database provides a comprehensive, high quality and freely available source of protein sequence and function information.
T59 6647-6807 Sentence denotes The putative target information corresponding to the active ingredients were input into UniProt database to obtain the standard name of the action target genes.
T60 6809-6841 Sentence denotes Screening of NCP related targets
T61 6842-6898 Sentence denotes COVID-19 is a type of Novel Coronavirus Pneumonia (NCP).
T62 6899-7125 Sentence denotes So We collected NCP related targets from GeneCards (https://www.genecards.org/), which is a searchable, integrative database that provides comprehensive, user-friendly information on all annotated and predicted human genes 29.
T63 7126-7204 Sentence denotes The key word “Novel Coronavirus Pneumonia” was used in the GeenCards database.
T64 7206-7307 Sentence denotes PPI (Protein-Protein Interaction) network construction of SFJDC putative and NCP related target genes
T65 7308-7449 Sentence denotes The PPI network of SFJDC putative and NCP related targets would be obtained from STRING (https://string-db.org/ ver11.0, update Jan 2019) 30.
T66 7450-7497 Sentence denotes Active interaction sources were set as follows:
T67 7498-7593 Sentence denotes Textmining, Co-expression, Neighborhood, Experiments, Databases, Gene Fusion and Co-occurrence.
T68 7594-7723 Sentence denotes The required minimum interaction score was set at 0.4 in PPI network of SFJDC related targets, PPI network of NCP was set at 0.9.
T69 7724-7829 Sentence denotes The barplot were generated by the R software (https://www.r-project.org/ver 3.6.2) based on counts value.
T70 7831-7878 Sentence denotes Construction of SFJDC ingredient-target network
T71 7879-8010 Sentence denotes Perl (https://www.perl.org/get.html) is a programming language suitable for writing simple scripts as well as complex applications.
T72 8011-8085 Sentence denotes We used Strawberry Perl 5.30.1.1 to prepare the ingredient-target network.
T73 8086-8218 Sentence denotes Cytoscape is a universal open source software for large-scale integrated development of molecular interaction networks working data.
T74 8219-8315 Sentence denotes Then the ingredients-targets network of SFJDC was constructed using Cytoscape 3.7.2 software 31.
T75 8317-8362 Sentence denotes PPI network construction of SFJDC against NCP
T76 8363-8522 Sentence denotes In order to reveal the mechanism of SFJDC against NCP, a PPI network was constructed by the BisoGenet client which is a Cytoscape plugin was used to visualize.
T77 8523-8640 Sentence denotes In this plugin, Protein-protein interactions information is taken from the DIP, BIOGRID, HPRD, INTACT, MINT, BIND 32.
T78 8641-8971 Sentence denotes CytoNCA is a Cytoscape plugin integrating calculation, evaluation and visualization analysis for multiple centrality measure measures including Betweenness Centrality (BC), Degree Centrality (DC), Colseness Centrality (CC), Local average connectivity-based method (LAC), Eigenvector Centrality (EC) and Network Centrality (NC) 33.
T79 8973-9043 Sentence denotes Identification of candidate genes (CGs) and enrichment analysis of CGs
T80 9044-9178 Sentence denotes The CGs were filtered with R software using the Venn Diagram package (https://cran.r-project.org/web/packages/VennDiagram/index.html).
T81 9179-9387 Sentence denotes The CGs would be used for Gene Ontology (GO) analysis (including biological processes (BP), molecular functions (MF), and cellular components (CC)) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways.
T82 9388-9666 Sentence denotes GO and KEGG pathway analyses results were processed by the “enrichplot” (http://www.bioconductor.org/packages/release/bioc/html/enrichplot.html) “clusterProfiler” (http://www.bioconductor.org/packages/release/bioc/html/clusterProfiler.html) and “ggplot2” packages by R software.
T83 9667-9742 Sentence denotes A P value of less than 0.05 was used regarded as statistically significant.
T84 9743-9878 Sentence denotes At the same time, we input CGs into DAVID (https://david.ncifcrf.gov/) for functional enrichment analysis to obtain disease clustering.
T85 9880-9916 Sentence denotes Construction of gene-pathway network
T86 9917-9992 Sentence denotes KEGG pathways that had significant changes of P<0.05 were further analyzed.
T87 9993-10079 Sentence denotes The genes that significantly regulated pathways for gene-pathway network construction.
T88 10080-10160 Sentence denotes The key target genes of SFJDC against NCP were screened by gene-pathway network.
T89 10162-10169 Sentence denotes Results
T90 10171-10225 Sentence denotes The active ingredients of each herb contained in SFJDC
T91 10226-10421 Sentence denotes One hundred and thirty-seven active ingredients were screened out of TCMSP based on ADME, 4 in PCRR, 17 in FF, 25 in IR, 9 in HP, 7 in PR, 7 in VH, 1 in I, 67 in RB and 13 of which were repeated.
T92 10422-10565 Sentence denotes Finally, 124 candidate active components of each herb contained in SFJDC were screened for further analysis after removing duplation (Table 2).
T93 10567-10639 Sentence denotes Putative target genes of each herb in SFJDC and NCP related target genes
T94 10640-10791 Sentence denotes The 124 candidate active components were imported into TCMSP database and Uniport database to identify the Putative target genes of each herb in SFJDC.
T95 10792-10914 Sentence denotes One hundred and ten components were finally selected after removing 14 ingredients which did not link to any target genes.
T96 10915-10964 Sentence denotes The target genes of 110 compounds were collected.
T97 10965-11071 Sentence denotes 1705 genes were identified, 103 in PR, 209 in IR, 65 in HP, 1052 in RB, 75 in PCRR, 173 in FF and 27 in I.
T98 11072-11230 Sentence denotes There were 1585 genes of the eight herbs overlapped, which was suggestive of potential interaction between the compounds of SFJDCA in the course of treatment.
T99 11231-11303 Sentence denotes A total of 120 genes were identified after removing duplation (Table 3).
T100 11304-11388 Sentence denotes And 251 NCP related target genes were identified from Gene Cards database (Table 4).
T101 11389-11447 Sentence denotes PPI network of SFJDC putative and NCP related target genes
T102 11448-11552 Sentence denotes In this study, we constructed the PPI network of SFJDC putative and NCP related target genes separately.
T103 11553-11771 Sentence denotes The network of SFJDC putative target genes which minimum interaction score was set at 0.4 contained 119 nodes and 1108 edges which indicated the target genes interactions after removing the discrete points (Figure 2A).
T104 11772-11845 Sentence denotes According the PPI network, the top thirty genes were listed in Figure 2B.
T105 11846-11964 Sentence denotes After hiding the discrete points, NCP-related target genes PPI network contained 248 nodes and 1235 edges (Figure 2C).
T106 11965-12027 Sentence denotes Similarly, the first 30 related genes were shown in Figure 2D.
T107 12029-12069 Sentence denotes SFJDC ingredient-target network analysis
T108 12070-12195 Sentence denotes The ingredient-target network of SFJDC was constructed using the screened ingredients and their targets as shown in Figure 3.
T109 12196-12296 Sentence denotes The network contained 117 nodes and 419 edges which indicated the compound-target genes interaction.
T110 12297-12431 Sentence denotes A median of 110 candidate compouds was 5 degrees which indicating that most compounds of SFJDC were affected by multiple target genes.
T111 12432-12519 Sentence denotes The top three effective ingredient according were Wogonin, licochalcone a and acacetin.
T112 12520-12603 Sentence denotes Wogonin, licochalcone a and acacetin have 42, 30 and 23 target genes, respectively.
T113 12604-12698 Sentence denotes And the OB of Wogonin, licochalcone a and acacetin were 30.68, 40.79 and 34.97%, respectively.
T114 12699-12783 Sentence denotes Hence, they might be the crucial effective compounds of SFJDC according the network.
T115 12785-12826 Sentence denotes PPI network analysis of SFJDC against NCP
T116 12827-12901 Sentence denotes PPI network of SFJDC against NCP were visualized using Cytoscape software.
T117 12902-12974 Sentence denotes The network contained 2407 nodes and 53639 edges was shown in Figure 4A.
T118 12975-13097 Sentence denotes The average degree of all nodes was 44.5692 and we selected the nodes with more than 44.5692 degrees as significant genes.
T119 13098-13227 Sentence denotes A subnetwork of significant genes for SFJDC against NCP was constructed which consisted of 766 nodes and 28872 edges (Figure 4B).
T120 13228-13265 Sentence denotes The average value of BC was 711.9504.
T121 13266-13386 Sentence denotes The significant genes were further screened and a new network was constructed with 169 nodes and 4238 edges (Figure 4C).
T122 13387-13498 Sentence denotes 169 genes were eventually identified for SFJDC against NCP including 156 other human genes and 13 target genes.
T123 13500-13570 Sentence denotes Identification of candidate genes (CGs) and Enrichment analysis of CGs
T124 13571-13666 Sentence denotes Twenty-three candidate genes (CGs) were identified by using the VennDiagram package (Figure 5).
T125 13667-13743 Sentence denotes Then R software was used to perform GO and KEGG pathway analysis of the CGs.
T126 13744-13787 Sentence denotes GO of CGs was analyzed based on BP, CC, MF.
T127 13788-13871 Sentence denotes 1215 GO terms were significantly enriched (P<0.05), 1148 in BP, 28 in CC, 39 in MF.
T128 13872-13908 Sentence denotes Top 20 terms were shown in Figure 6.
T129 13909-13963 Sentence denotes The data of top 20 GO analysis were listed in Table 5.
T130 13964-14254 Sentence denotes Based on these GO terms data, we found that most significantly terms were response to lipopolysaccharide, response to molecule of bacterial origin, membrane raft, membrane microdomain, BH domain binding and death domain binding, suggested that SFJDC could treat NCP with multiple synergies.
T131 14255-14373 Sentence denotes The pathways that were significantly affected by SFJDC in the process of treating NCP were identified by KEGG pathway.
T132 14374-14429 Sentence denotes 110 KEGG pathways were significantly enriched (P<0.05).
T133 14430-14548 Sentence denotes Top twenty pathways were shown in Figure 7, color represented P value and size of the spot represented count of genes.
T134 14549-14871 Sentence denotes Based on the analysis of KEGG pathway data (Table 6), the top five pathways such as Kaposi sarcoma-associated herpesvirus infection, AGE-RAGE signaling pathway in diabetic complications, Human cytomegalovirus infection, IL-17 signaling pathway and Hepatitis B, might be the core pharmacological mechanism of SFJDC for NCP.
T135 14872-14988 Sentence denotes In this study, we chose the functional annotation clustering and set the classification stringency as high in DAVID.
T136 14989-15058 Sentence denotes A total of 20 functional annotation clusters were obtained (Table 7).
T137 15059-15130 Sentence denotes Annotation Cluster 1 (enrichment score 6.04) contains three categories:
T138 15131-15314 Sentence denotes Asthma, Bronchiolitis Viral, Respiratory Syncytial Virus Infections, respiratory syncytial virus bronchiolitis, and all of them were lung related diseases and Virus infection disease.
T139 15316-15345 Sentence denotes Gene-pathway network analysis
T140 15346-15484 Sentence denotes The construction of gene-pathway network is based on significant enrichment pathway and regulated these ways, which was shown in Figure 8.
T141 15485-15572 Sentence denotes The V shapes represented pathway and the squares represent target genes in the network.
T142 15573-15652 Sentence denotes The network showed that RELA was the core target gene which had largest degree.
T143 15653-15737 Sentence denotes Other five genes also had larger degree such as MAPK1, MAPK14, CASP3, CASP8 and IL6.
T144 15738-15816 Sentence denotes They might be the key target genes using SFJDC in the process of treating NCP.
T145 15817-15899 Sentence denotes All of the above analysis could reveal a new strategy for drug development on NCP.
T146 15901-15911 Sentence denotes Discussion
T147 15912-15992 Sentence denotes The theory of TCM has been formed and developed for thousands of years in China.
T148 15993-16117 Sentence denotes In China, TCM has a good therapeutic effect on COVID-19, which has been written into the diagnosis and treatment guidelines.
T149 16118-16259 Sentence denotes The guideline points out that the combination of traditional Chinese and western medicine should be strengthened in the treatment process 34.
T150 16260-16416 Sentence denotes SFJDC is a traditional Chinese medicine, mainly used to treat upper respiratory tract infections, such as influenza, sore throat, mumps, streptococcus, etc.
T151 16417-16420 Sentence denotes 21.
T152 16421-16494 Sentence denotes Now, SFJDC has become an effective drug for the treatment of COVID-19 35.
T153 16495-16629 Sentence denotes In recent years, the research on Chinese medicine prescriptions has developed to the level of effective parts, components, components.
T154 16630-16757 Sentence denotes Network pharmacology can better understand and demonstrate the interaction between multi-component multi-target and disease 36.
T155 16758-16898 Sentence denotes This study aims to analyze the active components and potential mechanism of SFJDC in the treatment of COVID-19 through network pharmacology.
T156 16899-17016 Sentence denotes In the present study, the ingredients-targets network of SFJDC was constructed using 110 ingredients and 120 targets.
T157 17017-17117 Sentence denotes The network contained 117 nodes and 419 edges which indicated the compound-target genes interaction.
T158 17118-17301 Sentence denotes The results showed that most compounds of SFJDC were affected by multiple target genes, such as Wogonin, licochalcone a and acacetin acted on 42, 30 and 23 target genes, respectively.
T159 17302-17374 Sentence denotes Various compounds of SFJDC may have the same targets to achieve synergy.
T160 17375-17541 Sentence denotes Wogonin, a naturally occurring flavonoid, has been shown to multi-activity, such as anti-inflammatory, anti-fibrosis, anti-cancer and chondroprotective properties 37.
T161 17542-17632 Sentence denotes Study showed that wogonin had an anti-infulenza activity by modulation of AMPK pathway 38.
T162 17633-17790 Sentence denotes Licochalcone a, a flavonoid extracted from licorice toot, was known for its anti-inflammatory, anti-cancer, anti-oxidative and anti-bacterial bioactivity 39.
T163 17791-17892 Sentence denotes Acacetin, a flavone compound, played an important role in anti-inflammatory and anti-peroxidative 40.
T164 17893-17968 Sentence denotes In addition, they have high OB and acacetin from 2 herbs (PR, IR) of SFJDC.
T165 17969-18074 Sentence denotes The three main ingredients were anti-inflammatory and COVID-19 caused by a series of inflammatory storms.
T166 18075-18159 Sentence denotes Hence, they might be the crucial effective compounds of SFJDC according the network.
T167 18160-18271 Sentence denotes PPI network of SFJDC against NCP were visualized using Cytoscape software to obtain the candidate target genes.
T168 18272-18405 Sentence denotes In order to obtain the more accurate genes, two parameters including DC and BC were used to screen nodes and structure a new network.
T169 18406-18517 Sentence denotes 169 genes were eventually identified for SFJDC against NCP including 156 other human genes and 13 target genes.
T170 18518-18602 Sentence denotes Twenty-three candidate genes (CGs) were identified by using the VennDiagram package.
T171 18603-18661 Sentence denotes CGs were enriched in BP, CC, MF by GO enrichment analysis.
T172 18662-18853 Sentence denotes Based on GO terms data, we found that some terms were response to lipopolysaccharide or bacterial origin, membrane raft, membrane microdomain, BH domain binding and cytokine receptor binding.
T173 18854-19057 Sentence denotes COVID-19 infections leaded to a strong immune response and inflammatory storm in which a large number of cytokines were activated, so SFJDC might regulate COVID-19 through the above biological processes.
T174 19058-19137 Sentence denotes SFJDC, as a TCM formula, has multi-component, multi-target-gene, multi-pathway.
T175 19138-19206 Sentence denotes In the present study, 110 KEGG pathways were significantly enriched.
T176 19207-19580 Sentence denotes Seven of the top 20 pathways were associated with viral infection including Kaposi sarcoma-associated herpesvirus infection, Human cytomegalovirus infection, Hepatitis B, Influenza A, Epstein-Barr virus infection, Human immunodeficiency virus 1 infection and Measles, and three were associated with lung disease contained tuberculosis, pertussis and small cell lung cancer.
T177 19581-19767 Sentence denotes Multiple targets of SFJDC may also inhibit the activation of cytokines and reduce inflammation by regulating cytokine pathways, such as IL-17 signaling pathway and TNF signaling pathway.
T178 19768-19843 Sentence denotes In this study, we obtained 20 functional annotation clusters through DAVID.
T179 19844-20040 Sentence denotes Annotation Cluster1 including Asthma, Bronchiolitis Viral, Respiratory Syncytial Virus Infections, respiratory syncytial virus bronchiolitis were lung related diseases and Virus infection disease.
T180 20041-20111 Sentence denotes Gene-pathway network was constructed to the core and key target genes.
T181 20112-20186 Sentence denotes The network showed that RELA had largest degree, was the core target gene.
T182 20187-20282 Sentence denotes Other top five genes such as MAPK1, MAPK14, CASP3, CASP8 and IL6 might be the key target genes.
T183 20283-20466 Sentence denotes The pathophysiological process of Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-COV-2) infection is similar to that of SARS-CoV infection, with a strong inflammatory response.
T184 20467-20797 Sentence denotes The SARS-COV-2 virus mainly targets respiratory epithelial cells, alveolar epithelial cells, vascular endothelial cells and pulmonary macrophages, all of which express Angiotensin converting enzyme 2 (ACE2) receptor, triggering the generation of pro- inflammatory cytokines and chemokines (including IL-6, TNF, IL-10 and MCP1) 41.
T185 20798-21000 Sentence denotes The NF-kB family member RELA is a widely expressed and effective transcriptional activator that activates the expression of many inflammatory through exposure to pathogens and inflammatory cytokines 42.
T186 21001-21062 Sentence denotes RELA may play an important role in the infection of COVID-19.
T187 21063-21270 Sentence denotes MAPK1 and MAPK14 are members of the MAPK family, which can regulate multiple cellular processes, such as response to oxidative stress, anti-inflammatory, immune response, apoptosis and cell proliferation 43.
T188 21271-21507 Sentence denotes Joseph et al showed SASR-CoV-2 could induce severe inflammation by directly activating p38 MAPK pathway and many p38 MAPK inhibitors are in the clinical stage and should be considered for clinical trial for severe COVID-19 infection 44.
T189 21508-21713 Sentence denotes CASP3 and CASP8, a family of cysteine-dependent proteases, play an important role in these events through activation of other apoptotic proteins mediated by proteolysis and cleavage of nuclear proteins 45.
T190 21714-21846 Sentence denotes In Krahling's study, infection of 293/ACE2 cells with SARS-CoV activated apoptosis-associated events, such as caspase3, caspase 846.
T191 21847-21981 Sentence denotes Therefore, we conclude that CASP3 and CASP8 may be activated and play an important role in the pathophysiological process of COVID-19.
T192 21982-22052 Sentence denotes Higher plasma level of IL-6 was found in ICU patients with COVID-1947.
T193 22053-22263 Sentence denotes Tocilizumab, a recombinant humanized anti-human IL-6 receptor monoclonal antibody, improved the clinical outcome in 20 severe and critical COVID-19 patients and is an effective treatment to reduce mortality 48.
T194 22264-22350 Sentence denotes It has been clinically confirmed that SFJDC is effective in the treatment of COVID-19.
T195 22351-22537 Sentence denotes Wang et al shown that conventional treatment combined with SFJDC treatment for 4 cases of COVID-19 patients could significantly improve symptoms and promote viral negative conversion 49.
T196 22538-22776 Sentence denotes Another study including 70 COVID-19 patients found that SFJDC combined with Arbidol for COVID-19 compared with single using Arbidol could significantly shorten the time of clinical symptoms improvement and COVID-19 negative conversion 50.
T197 22777-22886 Sentence denotes To summarise, the compound and targets of SFJDC were systematically studied by applying network pharmacology.
T198 22887-22971 Sentence denotes Wogonin, licochalcone a and acacetin regulated the most targets associated with NCP.
T199 22972-23096 Sentence denotes RELA, MAPK1, MAPK14, CASP3, CASP8 and IL6 were the core and key genes in the gene-network of SFJDC for the treatment of NCP.
T200 23097-23239 Sentence denotes SFJDC regulated novel coronavirus pneumonia by multi-compound and multi-target, which provided theoretical support for SFJDC against COVID-19.
T201 23240-23301 Sentence denotes More mechanism and roles require further clinical validation.

2_test

Id Subject Object Predicate Lexical cue
33029094-31978945-50187120 190-191 31978945 denotes 1
33029094-32030925-50187120 190-191 32030925 denotes 1
33029094-32004427-50187120 190-191 32004427 denotes 1
33029094-32029004-50187121 1279-1280 32029004 denotes 8
33029094-32122113-50187122 1575-1577 32122113 denotes 11
33029094-32172669-50187123 2200-2202 32172669 denotes 14
33029094-32029004-50187124 2384-2385 32029004 denotes 8
33029094-24241177-50187125 3092-3094 24241177 denotes 18
33029094-30308517-50187126 3401-3403 30308517 denotes 19
33029094-31734578-50187127 3514-3516 31734578 denotes 20
33029094-30395287-50187128 6522-6524 30395287 denotes 28
33029094-27322403-50187129 7122-7124 27322403 denotes 29
33029094-30476243-50187130 7446-7448 30476243 denotes 30
33029094-25451770-50187131 8312-8314 25451770 denotes 31
33029094-20163717-50187132 8637-8639 20163717 denotes 32
33029094-14597658-50187133 8968-8970 14597658 denotes 33
33029094-23787177-50187134 16754-16756 23787177 denotes 36
33029094-28237856-50187135 17538-17540 28237856 denotes 37
33029094-29521106-50187136 17629-17631 29521106 denotes 38
33029094-22400806-50187137 17787-17789 22400806 denotes 39
33029094-29243040-50187138 17889-17891 29243040 denotes 40
33029094-32346093-50187139 20794-20796 32346093 denotes 41
33029094-32101750-50187140 20997-20999 32101750 denotes 42
33029094-28550733-50187141 21267-21269 28550733 denotes 43
33029094-32422320-50187142 21504-21506 32422320 denotes 44
33029094-19109397-50187143 21842-21845 19109397 denotes 846
33029094-32350134-50187144 22260-22262 32350134 denotes 48
T81980 190-191 31978945 denotes 1
T37391 190-191 32030925 denotes 1
T34268 190-191 32004427 denotes 1
T23189 1279-1280 32029004 denotes 8
T14097 1575-1577 32122113 denotes 11
T94880 2200-2202 32172669 denotes 14
T65876 2384-2385 32029004 denotes 8
T9291 3092-3094 24241177 denotes 18
T86512 3401-3403 30308517 denotes 19
T88255 3514-3516 31734578 denotes 20
T70581 6522-6524 30395287 denotes 28
T45961 7122-7124 27322403 denotes 29
T62344 7446-7448 30476243 denotes 30
T30724 8312-8314 25451770 denotes 31
T82585 8637-8639 20163717 denotes 32
T70814 8968-8970 14597658 denotes 33
T10094 16754-16756 23787177 denotes 36
T33835 17538-17540 28237856 denotes 37
T23665 17629-17631 29521106 denotes 38
T6828 17787-17789 22400806 denotes 39
T7761 17889-17891 29243040 denotes 40
T53886 20794-20796 32346093 denotes 41
T53825 20997-20999 32101750 denotes 42
T29108 21267-21269 28550733 denotes 43
T27530 21504-21506 32422320 denotes 44
T42089 21842-21845 19109397 denotes 846
T80753 22260-22262 32350134 denotes 48