PMC:7530350 / 663-1498
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T5 | 534-539 | Body_part | denotes | serum | http://purl.org/sig/ont/fma/fma63083 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 534-539 | Body_part | denotes | serum | http://purl.obolibrary.org/obo/UBERON_0001977 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T6 | 80-88 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T7 | 133-141 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T7 | 396-400 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | male |
| T8 | 396-400 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | male |
| T9 | 609-610 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T10 | 636-638 | http://purl.obolibrary.org/obo/CLO_0008426 | denotes | pg |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T7 | 32-34 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T9 | 296-301 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T10 | 366-371 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T11 | 396-400 | Chemical | denotes | male | http://purl.obolibrary.org/obo/CHEBI_30780 |
| T12 | 415-420 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T13 | 459-464 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T14 | 550-552 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T16 | 569-574 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T17 | 598-603 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T18 | 811-813 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 30 | 32-36 | Gene | denotes | IL-6 | Gene:3569 |
| 31 | 550-554 | Gene | denotes | IL-6 | Gene:3569 |
| 32 | 811-815 | Gene | denotes | IL-6 | Gene:3569 |
| 33 | 47-55 | Species | denotes | patients | Tax:9606 |
| 34 | 102-110 | Species | denotes | patients | Tax:9606 |
| 35 | 220-228 | Species | denotes | patients | Tax:9606 |
| 36 | 80-88 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 37 | 133-141 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T10 | 0-155 | Sentence | denotes | Eleven studies provided data of IL-6 levels in patients with severe to critical COVID-19 (severe) and patients with mild to moderate COVID-19 (non-severe). |
| T11 | 156-210 | Sentence | denotes | The included studies were of moderate to high quality. |
| T12 | 211-372 | Sentence | denotes | The mean patients’ age was 60.9 years, ranging from 45.2 to 76.7 years in the severe group and 46.8 years, ranging from 37.9 to 61 years, in the nonsevere group. |
| T13 | 373-465 | Sentence | denotes | Fifty-two percent were male in the severe group, as compared to 46% in the non-severe group. |
| T14 | 466-650 | Sentence | denotes | An overall random effects meta-analysis showed significantly higher serum levels of IL-6 in the severe group than in the non-severe group with a mean difference of +23.1 pg/mL (95% CI: |
| T15 | 651-713 | Sentence | denotes | 12.42–33.79) and the overall effect of 4.24 (P-value < 0.001). |
| T16 | 714-835 | Sentence | denotes | Meta-regressions showed that neither age nor sex significantly influenced the mean difference of IL-6 between the groups. |