PMC:7519301 / 99-866
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 459-466 | Body_part | denotes | genomes | http://purl.org/sig/ont/fma/fma84116 |
| T2 | 493-500 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T3 | 38-46 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T4 | 48-56 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T5 | 48-52 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T6 | 291-299 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T7 | 291-295 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T8 | 448-456 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T9 | 448-452 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T10 | 686-694 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T11 | 686-690 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 24-29 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T3 | 102-103 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T4 | 139-144 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T5 | 159-160 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T6 | 521-524 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T7 | 717-718 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T1 | 493-500 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id | tao:has_standard_notation |
|---|---|---|---|---|---|---|
| 10 | 487-492 | Gene | denotes | Spike | Gene:43740568 | |
| 11 | 606-610 | Gene | denotes | ACE2 | Gene:59272 | |
| 12 | 48-58 | Species | denotes | SARS-CoV-2 | Tax:2697049 | |
| 13 | 291-301 | Species | denotes | SARS-CoV-2 | Tax:2697049 | |
| 14 | 448-458 | Species | denotes | SARS-CoV-2 | Tax:2697049 | |
| 15 | 686-696 | Species | denotes | SARS-CoV-2 | Tax:2697049 | |
| 16 | 38-46 | Disease | denotes | COVID-19 | MESH:C000657245 | |
| 17 | 506-511 | Mutation | denotes | D614G | p.D614G |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 0-134 | Sentence | denotes | The rapid spread of the virus causing COVID-19, SARS-CoV-2, raises questions about the possibility of a universally effective vaccine. |
| T4 | 135-244 | Sentence | denotes | The virus can mutate in a given individual, and these variants can be propagated across populations and time. |
| T5 | 245-340 | Sentence | denotes | To understand this process, we analyze 18,514 SARS-CoV-2 sequences sampled since December 2019. |
| T6 | 341-467 | Sentence | denotes | We find that neutral evolution, rather than adaptive selection, can explain the rare mutations seen across SARS-CoV-2 genomes. |
| T7 | 468-620 | Sentence | denotes | In the immunogenic Spike protein, the D614G mutation has become consensus, yet there is no evidence of mutations affecting binding to the ACE2 receptor. |
| T8 | 621-767 | Sentence | denotes | Our results suggest that, to date, the limited diversity seen in SARS-CoV-2 should not preclude a single vaccine from providing global protection. |