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PMC:7519301 / 7257-8661 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T26 513-519 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T27 796-803 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T28 986-994 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T29 1081-1089 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T66 647-656 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T67 679-684 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T68 820-828 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T69 820-824 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T70 1166-1174 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T71 1166-1170 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T72 1220-1228 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T73 1220-1224 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T73 38-43 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T74 55-61 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T75 228-229 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T76 291-296 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T77 387-388 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T78 439-440 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T79 690-697 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T80 727-728 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T81 729-734 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T82 888-893 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T83 910-916 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans
T84 1195-1201 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes humans

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T24 796-803 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T25 986-994 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T26 1081-1089 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
165 845-846 Gene denotes S Gene:43740568
166 55-61 Species denotes humans Tax:9606
167 679-684 Species denotes Ebola Tax:1570291
168 820-830 Species denotes SARS-CoV-2 Tax:2697049
169 910-916 Species denotes humans Tax:9606
170 1166-1176 Species denotes SARS-CoV-2 Tax:2697049
171 1195-1201 Species denotes humans Tax:9606
172 1220-1230 Species denotes SARS-CoV-2 Tax:2697049
173 647-656 Species denotes influenza Tax:11309
174 181-189 Disease denotes infected MESH:D007239
175 240-253 Disease denotes viral fitness
176 270-283 Disease denotes viral fitness
177 873-880 Disease denotes fitness MESH:D012640

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T46 0-62 Sentence denotes New mutations will be observed as the virus spreads in humans.
T47 63-190 Sentence denotes The viral evolutionary dynamics can be characterized by analyzing viral sequences sampled from individuals who became infected.
T48 191-254 Sentence denotes The accumulation of mutations can be a marker of viral fitness:
T49 255-520 Sentence denotes An increase in viral fitness as the virus adapts to its host will be associated with pervasive mutations at specific sites, whereas a neutral evolution context will be associated with a minimal number of fixed mutations distributed stochastically across the genome.
T50 521-698 Sentence denotes Indicators of viral evolution have been shown to be robust predictors of transmission dynamics for several pathogens, such as influenza (19), Lassa (20), and Ebola (21) viruses.
T51 699-804 Sentence denotes Typically, the evolution of a virus is driven by genotypic and phenotypic changes in its surface protein.
T52 805-917 Sentence denotes In the case of SARS-CoV-2, mutations in S are most likely to confer fitness to the virus as it adapts to humans.
T53 918-1202 Sentence denotes However, adaptive changes can occur in structural and nonstructural proteins, and these changes, as well as different patterns across structural and nonstructural proteins, may provide insights into the near- and long-term evolutionary dynamics of SARS-CoV-2, as it spreads in humans.
T54 1203-1404 Sentence denotes Here we analyzed SARS-CoV-2 sequences sampled since the beginning of the pandemic and found that mutations were rare, indicating that potential vaccine candidates should cover all circulating variants.