PMC:7519301 / 7257-8661
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T26 | 513-519 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
| T27 | 796-803 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T28 | 986-994 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
| T29 | 1081-1089 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T66 | 647-656 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T67 | 679-684 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
| T68 | 820-828 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T69 | 820-824 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T70 | 1166-1174 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T71 | 1166-1170 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T72 | 1220-1228 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T73 | 1220-1224 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T73 | 38-43 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T74 | 55-61 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T75 | 228-229 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T76 | 291-296 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T77 | 387-388 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T78 | 439-440 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T79 | 690-697 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T80 | 727-728 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T81 | 729-734 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T82 | 888-893 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T83 | 910-916 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
| T84 | 1195-1201 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T24 | 796-803 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T25 | 986-994 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
| T26 | 1081-1089 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 165 | 845-846 | Gene | denotes | S | Gene:43740568 |
| 166 | 55-61 | Species | denotes | humans | Tax:9606 |
| 167 | 679-684 | Species | denotes | Ebola | Tax:1570291 |
| 168 | 820-830 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 169 | 910-916 | Species | denotes | humans | Tax:9606 |
| 170 | 1166-1176 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 171 | 1195-1201 | Species | denotes | humans | Tax:9606 |
| 172 | 1220-1230 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 173 | 647-656 | Species | denotes | influenza | Tax:11309 |
| 174 | 181-189 | Disease | denotes | infected | MESH:D007239 |
| 175 | 240-253 | Disease | denotes | viral fitness | |
| 176 | 270-283 | Disease | denotes | viral fitness | |
| 177 | 873-880 | Disease | denotes | fitness | MESH:D012640 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T46 | 0-62 | Sentence | denotes | New mutations will be observed as the virus spreads in humans. |
| T47 | 63-190 | Sentence | denotes | The viral evolutionary dynamics can be characterized by analyzing viral sequences sampled from individuals who became infected. |
| T48 | 191-254 | Sentence | denotes | The accumulation of mutations can be a marker of viral fitness: |
| T49 | 255-520 | Sentence | denotes | An increase in viral fitness as the virus adapts to its host will be associated with pervasive mutations at specific sites, whereas a neutral evolution context will be associated with a minimal number of fixed mutations distributed stochastically across the genome. |
| T50 | 521-698 | Sentence | denotes | Indicators of viral evolution have been shown to be robust predictors of transmission dynamics for several pathogens, such as influenza (19), Lassa (20), and Ebola (21) viruses. |
| T51 | 699-804 | Sentence | denotes | Typically, the evolution of a virus is driven by genotypic and phenotypic changes in its surface protein. |
| T52 | 805-917 | Sentence | denotes | In the case of SARS-CoV-2, mutations in S are most likely to confer fitness to the virus as it adapts to humans. |
| T53 | 918-1202 | Sentence | denotes | However, adaptive changes can occur in structural and nonstructural proteins, and these changes, as well as different patterns across structural and nonstructural proteins, may provide insights into the near- and long-term evolutionary dynamics of SARS-CoV-2, as it spreads in humans. |
| T54 | 1203-1404 | Sentence | denotes | Here we analyzed SARS-CoV-2 sequences sampled since the beginning of the pandemic and found that mutations were rare, indicating that potential vaccine candidates should cover all circulating variants. |