PMC:7519301 / 478-906 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7519301","sourcedb":"PMC","sourceid":"7519301","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7519301","text":" than adaptive selection, can explain the rare mutations seen across SARS-CoV-2 genomes. In the immunogenic Spike protein, the D614G mutation has become consensus, yet there is no evidence of mutations affecting binding to the ACE2 receptor. Our results suggest that, to date, the limited diversity seen in SARS-CoV-2 should not preclude a single vaccine from providing global protection.\n\nAbstract\nThe magnitude of the COVID-19","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T1","span":{"begin":80,"end":87},"obj":"Body_part"},{"id":"T2","span":{"begin":114,"end":121},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma67257"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T8","span":{"begin":69,"end":77},"obj":"Disease"},{"id":"T9","span":{"begin":69,"end":73},"obj":"Disease"},{"id":"T10","span":{"begin":307,"end":315},"obj":"Disease"},{"id":"T11","span":{"begin":307,"end":311},"obj":"Disease"},{"id":"T12","span":{"begin":420,"end":428},"obj":"Disease"}],"attributes":[{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T9","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T10","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T11","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T12","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T6","span":{"begin":142,"end":145},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T7","span":{"begin":338,"end":339},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T6","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":114,"end":121},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"subj":"T1","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"10","span":{"begin":108,"end":113},"obj":"Gene"},{"id":"11","span":{"begin":227,"end":231},"obj":"Gene"},{"id":"14","span":{"begin":69,"end":79},"obj":"Species"},{"id":"15","span":{"begin":307,"end":317},"obj":"Species"},{"id":"17","span":{"begin":127,"end":132},"obj":"Mutation"},{"id":"37","span":{"begin":420,"end":428},"obj":"Disease"}],"attributes":[{"id":"A10","pred":"tao:has_database_id","subj":"10","obj":"Gene:43740568"},{"id":"A11","pred":"tao:has_database_id","subj":"11","obj":"Gene:59272"},{"id":"A14","pred":"tao:has_database_id","subj":"14","obj":"Tax:2697049"},{"id":"A15","pred":"tao:has_database_id","subj":"15","obj":"Tax:2697049"},{"id":"A17","pred":"tao:has_standard_notation","subj":"17","obj":"p.D614G"},{"id":"A37","pred":"tao:has_database_id","subj":"37","obj":"MESH:C000657245"},{"subj":"10","pred":"source","obj":"LitCovid-PubTator"},{"subj":"11","pred":"source","obj":"LitCovid-PubTator"},{"subj":"14","pred":"source","obj":"LitCovid-PubTator"},{"subj":"15","pred":"source","obj":"LitCovid-PubTator"},{"subj":"17","pred":"source","obj":"LitCovid-PubTator"},{"subj":"37","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T7","span":{"begin":89,"end":241},"obj":"Sentence"},{"id":"T8","span":{"begin":242,"end":388},"obj":"Sentence"},{"id":"T9","span":{"begin":390,"end":398},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T7","pred":"source","obj":"LitCovid-sentences"},{"subj":"T8","pred":"source","obj":"LitCovid-sentences"},{"subj":"T9","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#9bec93","default":true},{"id":"LitCovid-PD-MONDO","color":"#ec93b5"},{"id":"LitCovid-PD-CLO","color":"#93cfec"},{"id":"LitCovid-PD-CHEBI","color":"#e9ec93"},{"id":"LitCovid-PubTator","color":"#d593ec"},{"id":"LitCovid-sentences","color":"#93ecbb"}]}]}}