PMC:7502678 / 17122-18167 JSONTXT

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    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T83","span":{"begin":87,"end":95},"obj":"Disease"},{"id":"T84","span":{"begin":154,"end":156},"obj":"Disease"},{"id":"T85","span":{"begin":233,"end":241},"obj":"Disease"},{"id":"T86","span":{"begin":283,"end":291},"obj":"Disease"},{"id":"T87","span":{"begin":388,"end":396},"obj":"Disease"},{"id":"T88","span":{"begin":405,"end":424},"obj":"Disease"},{"id":"T89","span":{"begin":583,"end":591},"obj":"Disease"},{"id":"T90","span":{"begin":740,"end":748},"obj":"Disease"},{"id":"T91","span":{"begin":972,"end":980},"obj":"Disease"},{"id":"T92","span":{"begin":1012,"end":1014},"obj":"Disease"}],"attributes":[{"id":"A83","pred":"mondo_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A84","pred":"mondo_id","subj":"T84","obj":"http://purl.obolibrary.org/obo/MONDO_0002125"},{"id":"A85","pred":"mondo_id","subj":"T85","obj":"http://purl.obolibrary.org/obo/MONDO_0005027"},{"id":"A86","pred":"mondo_id","subj":"T86","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A87","pred":"mondo_id","subj":"T87","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A88","pred":"mondo_id","subj":"T88","obj":"http://purl.obolibrary.org/obo/MONDO_0005845"},{"id":"A89","pred":"mondo_id","subj":"T89","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A90","pred":"mondo_id","subj":"T90","obj":"http://purl.obolibrary.org/obo/MONDO_0005027"},{"id":"A91","pred":"mondo_id","subj":"T91","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A92","pred":"mondo_id","subj":"T92","obj":"http://purl.obolibrary.org/obo/MONDO_0002125"}],"text":"There are very few data regarding the type of new-onset seizures seen in patients with COVID-19 in the literature. There is a single case report of focal SE as a presenting manifestation in a patient with underlying postencephalitic epilepsy.8 A small case series of 7 patients with COVID-19 presenting with seizures, of which 4 had new-onset seizures, has been reported.9 A patient with COVID-19 related meningoencephalitis was reported to have generalized seizures lasting about a minute.7 One EEG-based case series demonstrates abnormalities seen in encephalopathic patients with COVID-19, including generalized slowing, generalized epileptiform discharges and focal seizures, although many of the patients in the series had preexisting epilepsy.10 In this study, there were 2 patients with focal seizures, 1 was new onset and 1 was in a PWE. Additionally, in this study several patients had generalized periodic discharges of triphasic morphology. Other patients with COVID-19 related new onset seizures and SE have also been described.11,12"}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T65","span":{"begin":124,"end":125},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T66","span":{"begin":160,"end":161},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T67","span":{"begin":190,"end":191},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T68","span":{"begin":244,"end":245},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T69","span":{"begin":353,"end":356},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T70","span":{"begin":373,"end":374},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T71","span":{"begin":481,"end":482},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T72","span":{"begin":839,"end":840},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"There are very few data regarding the type of new-onset seizures seen in patients with COVID-19 in the literature. There is a single case report of focal SE as a presenting manifestation in a patient with underlying postencephalitic epilepsy.8 A small case series of 7 patients with COVID-19 presenting with seizures, of which 4 had new-onset seizures, has been reported.9 A patient with COVID-19 related meningoencephalitis was reported to have generalized seizures lasting about a minute.7 One EEG-based case series demonstrates abnormalities seen in encephalopathic patients with COVID-19, including generalized slowing, generalized epileptiform discharges and focal seizures, although many of the patients in the series had preexisting epilepsy.10 In this study, there were 2 patients with focal seizures, 1 was new onset and 1 was in a PWE. Additionally, in this study several patients had generalized periodic discharges of triphasic morphology. Other patients with COVID-19 related new onset seizures and SE have also been described.11,12"}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T18","span":{"begin":154,"end":156},"obj":"Chemical"},{"id":"T19","span":{"begin":496,"end":499},"obj":"Chemical"},{"id":"T20","span":{"begin":1012,"end":1014},"obj":"Chemical"}],"attributes":[{"id":"A18","pred":"chebi_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CHEBI_74813"},{"id":"A19","pred":"chebi_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/CHEBI_73494"},{"id":"A20","pred":"chebi_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CHEBI_74813"}],"text":"There are very few data regarding the type of new-onset seizures seen in patients with COVID-19 in the literature. There is a single case report of focal SE as a presenting manifestation in a patient with underlying postencephalitic epilepsy.8 A small case series of 7 patients with COVID-19 presenting with seizures, of which 4 had new-onset seizures, has been reported.9 A patient with COVID-19 related meningoencephalitis was reported to have generalized seizures lasting about a minute.7 One EEG-based case series demonstrates abnormalities seen in encephalopathic patients with COVID-19, including generalized slowing, generalized epileptiform discharges and focal seizures, although many of the patients in the series had preexisting epilepsy.10 In this study, there were 2 patients with focal seizures, 1 was new onset and 1 was in a PWE. Additionally, in this study several patients had generalized periodic discharges of triphasic morphology. Other patients with COVID-19 related new onset seizures and SE have also been described.11,12"}

    LitCovid-PubTator

    {"project":"LitCovid-PubTator","denotations":[{"id":"328","span":{"begin":73,"end":81},"obj":"Species"},{"id":"329","span":{"begin":192,"end":199},"obj":"Species"},{"id":"330","span":{"begin":269,"end":277},"obj":"Species"},{"id":"331","span":{"begin":375,"end":382},"obj":"Species"},{"id":"332","span":{"begin":569,"end":577},"obj":"Species"},{"id":"333","span":{"begin":701,"end":709},"obj":"Species"},{"id":"334","span":{"begin":780,"end":788},"obj":"Species"},{"id":"335","span":{"begin":882,"end":890},"obj":"Species"},{"id":"336","span":{"begin":958,"end":966},"obj":"Species"},{"id":"337","span":{"begin":56,"end":64},"obj":"Disease"},{"id":"338","span":{"begin":87,"end":95},"obj":"Disease"},{"id":"339","span":{"begin":154,"end":156},"obj":"Disease"},{"id":"340","span":{"begin":216,"end":241},"obj":"Disease"},{"id":"341","span":{"begin":283,"end":291},"obj":"Disease"},{"id":"342","span":{"begin":308,"end":316},"obj":"Disease"},{"id":"343","span":{"begin":343,"end":351},"obj":"Disease"},{"id":"344","span":{"begin":388,"end":396},"obj":"Disease"},{"id":"345","span":{"begin":405,"end":424},"obj":"Disease"},{"id":"346","span":{"begin":458,"end":466},"obj":"Disease"},{"id":"347","span":{"begin":553,"end":568},"obj":"Disease"},{"id":"348","span":{"begin":583,"end":591},"obj":"Disease"},{"id":"349","span":{"begin":636,"end":659},"obj":"Disease"},{"id":"350","span":{"begin":670,"end":678},"obj":"Disease"},{"id":"351","span":{"begin":740,"end":748},"obj":"Disease"},{"id":"352","span":{"begin":800,"end":808},"obj":"Disease"},{"id":"353","span":{"begin":972,"end":980},"obj":"Disease"},{"id":"354","span":{"begin":999,"end":1007},"obj":"Disease"},{"id":"355","span":{"begin":1012,"end":1014},"obj":"Disease"}],"attributes":[{"id":"A328","pred":"tao:has_database_id","subj":"328","obj":"Tax:9606"},{"id":"A329","pred":"tao:has_database_id","subj":"329","obj":"Tax:9606"},{"id":"A330","pred":"tao:has_database_id","subj":"330","obj":"Tax:9606"},{"id":"A331","pred":"tao:has_database_id","subj":"331","obj":"Tax:9606"},{"id":"A332","pred":"tao:has_database_id","subj":"332","obj":"Tax:9606"},{"id":"A333","pred":"tao:has_database_id","subj":"333","obj":"Tax:9606"},{"id":"A334","pred":"tao:has_database_id","subj":"334","obj":"Tax:9606"},{"id":"A335","pred":"tao:has_database_id","subj":"335","obj":"Tax:9606"},{"id":"A336","pred":"tao:has_database_id","subj":"336","obj":"Tax:9606"},{"id":"A337","pred":"tao:has_database_id","subj":"337","obj":"MESH:D012640"},{"id":"A338","pred":"tao:has_database_id","subj":"338","obj":"MESH:C000657245"},{"id":"A340","pred":"tao:has_database_id","subj":"340","obj":"MESH:D010301"},{"id":"A341","pred":"tao:has_database_id","subj":"341","obj":"MESH:C000657245"},{"id":"A342","pred":"tao:has_database_id","subj":"342","obj":"MESH:D012640"},{"id":"A343","pred":"tao:has_database_id","subj":"343","obj":"MESH:D012640"},{"id":"A344","pred":"tao:has_database_id","subj":"344","obj":"MESH:C000657245"},{"id":"A345","pred":"tao:has_database_id","subj":"345","obj":"MESH:D008590"},{"id":"A346","pred":"tao:has_database_id","subj":"346","obj":"MESH:D012640"},{"id":"A348","pred":"tao:has_database_id","subj":"348","obj":"MESH:C000657245"},{"id":"A349","pred":"tao:has_database_id","subj":"349","obj":"MESH:D019522"},{"id":"A350","pred":"tao:has_database_id","subj":"350","obj":"MESH:D012640"},{"id":"A351","pred":"tao:has_database_id","subj":"351","obj":"MESH:D004827"},{"id":"A352","pred":"tao:has_database_id","subj":"352","obj":"MESH:D012640"},{"id":"A353","pred":"tao:has_database_id","subj":"353","obj":"MESH:C000657245"},{"id":"A354","pred":"tao:has_database_id","subj":"354","obj":"MESH:D012640"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"There are very few data regarding the type of new-onset seizures seen in patients with COVID-19 in the literature. There is a single case report of focal SE as a presenting manifestation in a patient with underlying postencephalitic epilepsy.8 A small case series of 7 patients with COVID-19 presenting with seizures, of which 4 had new-onset seizures, has been reported.9 A patient with COVID-19 related meningoencephalitis was reported to have generalized seizures lasting about a minute.7 One EEG-based case series demonstrates abnormalities seen in encephalopathic patients with COVID-19, including generalized slowing, generalized epileptiform discharges and focal seizures, although many of the patients in the series had preexisting epilepsy.10 In this study, there were 2 patients with focal seizures, 1 was new onset and 1 was in a PWE. Additionally, in this study several patients had generalized periodic discharges of triphasic morphology. Other patients with COVID-19 related new onset seizures and SE have also been described.11,12"}

    LitCovid-PD-HP

    {"project":"LitCovid-PD-HP","denotations":[{"id":"T64","span":{"begin":56,"end":64},"obj":"Phenotype"},{"id":"T65","span":{"begin":154,"end":156},"obj":"Phenotype"},{"id":"T66","span":{"begin":233,"end":241},"obj":"Phenotype"},{"id":"T67","span":{"begin":308,"end":316},"obj":"Phenotype"},{"id":"T68","span":{"begin":343,"end":351},"obj":"Phenotype"},{"id":"T69","span":{"begin":446,"end":466},"obj":"Phenotype"},{"id":"T70","span":{"begin":664,"end":678},"obj":"Phenotype"},{"id":"T71","span":{"begin":740,"end":748},"obj":"Phenotype"},{"id":"T72","span":{"begin":794,"end":808},"obj":"Phenotype"},{"id":"T73","span":{"begin":999,"end":1007},"obj":"Phenotype"},{"id":"T74","span":{"begin":1012,"end":1014},"obj":"Phenotype"}],"attributes":[{"id":"A64","pred":"hp_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/HP_0001250"},{"id":"A65","pred":"hp_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/HP_0002133"},{"id":"A66","pred":"hp_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/HP_0001250"},{"id":"A67","pred":"hp_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/HP_0001250"},{"id":"A68","pred":"hp_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/HP_0001250"},{"id":"A69","pred":"hp_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/HP_0002197"},{"id":"A70","pred":"hp_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/HP_0007359"},{"id":"A71","pred":"hp_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/HP_0001250"},{"id":"A72","pred":"hp_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/HP_0007359"},{"id":"A73","pred":"hp_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/HP_0001250"},{"id":"A74","pred":"hp_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/HP_0002133"}],"text":"There are very few data regarding the type of new-onset seizures seen in patients with COVID-19 in the literature. There is a single case report of focal SE as a presenting manifestation in a patient with underlying postencephalitic epilepsy.8 A small case series of 7 patients with COVID-19 presenting with seizures, of which 4 had new-onset seizures, has been reported.9 A patient with COVID-19 related meningoencephalitis was reported to have generalized seizures lasting about a minute.7 One EEG-based case series demonstrates abnormalities seen in encephalopathic patients with COVID-19, including generalized slowing, generalized epileptiform discharges and focal seizures, although many of the patients in the series had preexisting epilepsy.10 In this study, there were 2 patients with focal seizures, 1 was new onset and 1 was in a PWE. Additionally, in this study several patients had generalized periodic discharges of triphasic morphology. Other patients with COVID-19 related new onset seizures and SE have also been described.11,12"}

    0_colil

    {"project":"0_colil","denotations":[{"id":"32942901-32344366-1069","span":{"begin":242,"end":243},"obj":"32344366"},{"id":"32942901-32739397-1070","span":{"begin":371,"end":372},"obj":"32739397"},{"id":"32942901-32251791-1071","span":{"begin":490,"end":491},"obj":"32251791"},{"id":"32942901-32578124-1072","span":{"begin":1040,"end":1042},"obj":"32578124"}],"text":"There are very few data regarding the type of new-onset seizures seen in patients with COVID-19 in the literature. There is a single case report of focal SE as a presenting manifestation in a patient with underlying postencephalitic epilepsy.8 A small case series of 7 patients with COVID-19 presenting with seizures, of which 4 had new-onset seizures, has been reported.9 A patient with COVID-19 related meningoencephalitis was reported to have generalized seizures lasting about a minute.7 One EEG-based case series demonstrates abnormalities seen in encephalopathic patients with COVID-19, including generalized slowing, generalized epileptiform discharges and focal seizures, although many of the patients in the series had preexisting epilepsy.10 In this study, there were 2 patients with focal seizures, 1 was new onset and 1 was in a PWE. Additionally, in this study several patients had generalized periodic discharges of triphasic morphology. Other patients with COVID-19 related new onset seizures and SE have also been described.11,12"}

    TEST0

    {"project":"TEST0","denotations":[{"id":"32942901-236-241-1069","span":{"begin":242,"end":243},"obj":"[\"32344366\"]"},{"id":"32942901-238-243-1070","span":{"begin":371,"end":372},"obj":"[\"32739397\"]"},{"id":"32942901-119-124-1071","span":{"begin":490,"end":491},"obj":"[\"32251791\"]"},{"id":"32942901-88-94-1072","span":{"begin":1040,"end":1042},"obj":"[\"32578124\"]"}],"text":"There are very few data regarding the type of new-onset seizures seen in patients with COVID-19 in the literature. There is a single case report of focal SE as a presenting manifestation in a patient with underlying postencephalitic epilepsy.8 A small case series of 7 patients with COVID-19 presenting with seizures, of which 4 had new-onset seizures, has been reported.9 A patient with COVID-19 related meningoencephalitis was reported to have generalized seizures lasting about a minute.7 One EEG-based case series demonstrates abnormalities seen in encephalopathic patients with COVID-19, including generalized slowing, generalized epileptiform discharges and focal seizures, although many of the patients in the series had preexisting epilepsy.10 In this study, there were 2 patients with focal seizures, 1 was new onset and 1 was in a PWE. Additionally, in this study several patients had generalized periodic discharges of triphasic morphology. Other patients with COVID-19 related new onset seizures and SE have also been described.11,12"}

    2_test

    {"project":"2_test","denotations":[{"id":"32942901-32344366-28639241","span":{"begin":242,"end":243},"obj":"32344366"},{"id":"32942901-32739397-28639242","span":{"begin":371,"end":372},"obj":"32739397"},{"id":"32942901-32251791-28639243","span":{"begin":490,"end":491},"obj":"32251791"},{"id":"32942901-32578124-28639244","span":{"begin":1040,"end":1042},"obj":"32578124"}],"text":"There are very few data regarding the type of new-onset seizures seen in patients with COVID-19 in the literature. There is a single case report of focal SE as a presenting manifestation in a patient with underlying postencephalitic epilepsy.8 A small case series of 7 patients with COVID-19 presenting with seizures, of which 4 had new-onset seizures, has been reported.9 A patient with COVID-19 related meningoencephalitis was reported to have generalized seizures lasting about a minute.7 One EEG-based case series demonstrates abnormalities seen in encephalopathic patients with COVID-19, including generalized slowing, generalized epileptiform discharges and focal seizures, although many of the patients in the series had preexisting epilepsy.10 In this study, there were 2 patients with focal seizures, 1 was new onset and 1 was in a PWE. Additionally, in this study several patients had generalized periodic discharges of triphasic morphology. Other patients with COVID-19 related new onset seizures and SE have also been described.11,12"}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T136","span":{"begin":0,"end":114},"obj":"Sentence"},{"id":"T137","span":{"begin":115,"end":845},"obj":"Sentence"},{"id":"T138","span":{"begin":846,"end":951},"obj":"Sentence"},{"id":"T139","span":{"begin":952,"end":1045},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"There are very few data regarding the type of new-onset seizures seen in patients with COVID-19 in the literature. There is a single case report of focal SE as a presenting manifestation in a patient with underlying postencephalitic epilepsy.8 A small case series of 7 patients with COVID-19 presenting with seizures, of which 4 had new-onset seizures, has been reported.9 A patient with COVID-19 related meningoencephalitis was reported to have generalized seizures lasting about a minute.7 One EEG-based case series demonstrates abnormalities seen in encephalopathic patients with COVID-19, including generalized slowing, generalized epileptiform discharges and focal seizures, although many of the patients in the series had preexisting epilepsy.10 In this study, there were 2 patients with focal seizures, 1 was new onset and 1 was in a PWE. Additionally, in this study several patients had generalized periodic discharges of triphasic morphology. Other patients with COVID-19 related new onset seizures and SE have also been described.11,12"}

    MyTest

    {"project":"MyTest","denotations":[{"id":"32942901-32344366-28639241","span":{"begin":242,"end":244},"obj":"32344366"},{"id":"32942901-32739397-28639242","span":{"begin":371,"end":373},"obj":"32739397"},{"id":"32942901-32251791-28639243","span":{"begin":490,"end":492},"obj":"32251791"},{"id":"32942901-32578124-28639244","span":{"begin":1040,"end":1042},"obj":"32578124"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"There are very few data regarding the type of new-onset seizures seen in patients with COVID-19 in the literature. There is a single case report of focal SE as a presenting manifestation in a patient with underlying postencephalitic epilepsy.8 A small case series of 7 patients with COVID-19 presenting with seizures, of which 4 had new-onset seizures, has been reported.9 A patient with COVID-19 related meningoencephalitis was reported to have generalized seizures lasting about a minute.7 One EEG-based case series demonstrates abnormalities seen in encephalopathic patients with COVID-19, including generalized slowing, generalized epileptiform discharges and focal seizures, although many of the patients in the series had preexisting epilepsy.10 In this study, there were 2 patients with focal seizures, 1 was new onset and 1 was in a PWE. Additionally, in this study several patients had generalized periodic discharges of triphasic morphology. Other patients with COVID-19 related new onset seizures and SE have also been described.11,12"}