PMC:7499668
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T1 | 155-167 | Body_part | denotes | aortic valve | http://purl.org/sig/ont/fma/fma7236 |
| T2 | 408-425 | Body_part | denotes | base of the heart | http://purl.org/sig/ont/fma/fma223286 |
| T3 | 420-425 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T4 | 452-460 | Body_part | denotes | troponin | http://purl.org/sig/ont/fma/fma62338 |
| T5 | 476-486 | Body_part | denotes | troponin T | http://purl.org/sig/ont/fma/fma67900 |
| T6 | 476-484 | Body_part | denotes | troponin | http://purl.org/sig/ont/fma/fma62338 |
| T7 | 570-575 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
| T8 | 931-943 | Body_part | denotes | aortic valve | http://purl.org/sig/ont/fma/fma7236 |
| T9 | 998-1012 | Body_part | denotes | left ventricle | http://purl.org/sig/ont/fma/fma7101 |
| T10 | 1067-1082 | Body_part | denotes | right ventricle | http://purl.org/sig/ont/fma/fma7098 |
| T11 | 1109-1114 | Body_part | denotes | chest | http://purl.org/sig/ont/fma/fma9576 |
| T12 | 1264-1269 | Body_part | denotes | heart | http://purl.org/sig/ont/fma/fma7088 |
| T13 | 1366-1376 | Body_part | denotes | adrenaline | http://purl.org/sig/ont/fma/fma67243 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 155-167 | Body_part | denotes | aortic valve | http://purl.obolibrary.org/obo/UBERON_0002137 |
| T2 | 162-167 | Body_part | denotes | valve | http://purl.obolibrary.org/obo/UBERON_0003978 |
| T3 | 420-425 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
| T4 | 570-575 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T5 | 931-943 | Body_part | denotes | aortic valve | http://purl.obolibrary.org/obo/UBERON_0002137 |
| T6 | 938-943 | Body_part | denotes | valve | http://purl.obolibrary.org/obo/UBERON_0003978 |
| T7 | 1109-1114 | Body_part | denotes | chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
| T8 | 1264-1269 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 31-39 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T2 | 74-96 | Disease | denotes | infective endocarditis | http://purl.obolibrary.org/obo/MONDO_0000565 |
| T3 | 84-96 | Disease | denotes | endocarditis | http://purl.obolibrary.org/obo/MONDO_0005025 |
| T4 | 146-167 | Disease | denotes | bicuspid aortic valve | http://purl.obolibrary.org/obo/MONDO_0013902|http://purl.obolibrary.org/obo/MONDO_0024523 |
| T6 | 173-191 | Disease | denotes | aortic coarctation | http://purl.obolibrary.org/obo/MONDO_0007345 |
| T7 | 248-257 | Disease | denotes | diarrhoea | http://purl.obolibrary.org/obo/MONDO_0001673 |
| T8 | 650-661 | Disease | denotes | pneumonitis | http://purl.obolibrary.org/obo/MONDO_0043905 |
| T9 | 688-690 | Disease | denotes | he | http://purl.obolibrary.org/obo/MONDO_0017319 |
| T10 | 804-814 | Disease | denotes | (AV) block | http://purl.obolibrary.org/obo/MONDO_0000465 |
| T11 | 891-911 | Disease | denotes | aortic regurgitation | http://purl.obolibrary.org/obo/MONDO_0005648 |
| T12 | 972-979 | Disease | denotes | abscess | http://purl.obolibrary.org/obo/MONDO_0005227 |
| T13 | 1186-1194 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T14 | 1195-1206 | Disease | denotes | pneumonitis | http://purl.obolibrary.org/obo/MONDO_0043905 |
| T15 | 1255-1275 | Disease | denotes | complete heart block | http://purl.obolibrary.org/obo/MONDO_0000468 |
| T16 | 1505-1513 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T17 | 1598-1620 | Disease | denotes | infective endocarditis | http://purl.obolibrary.org/obo/MONDO_0000565 |
| T18 | 1608-1620 | Disease | denotes | endocarditis | http://purl.obolibrary.org/obo/MONDO_0005025 |
| T19 | 1646-1655 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 100-101 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T2 | 117-121 | http://purl.obolibrary.org/obo/CLO_0001564 | denotes | A 20 |
| T3 | 117-121 | http://purl.obolibrary.org/obo/CLO_0050194 | denotes | A 20 |
| T4 | 155-161 | http://www.ebi.ac.uk/efo/EFO_0000265 | denotes | aortic |
| T5 | 162-167 | http://www.ebi.ac.uk/efo/EFO_0000825 | denotes | valve |
| T6 | 173-179 | http://www.ebi.ac.uk/efo/EFO_0000265 | denotes | aortic |
| T7 | 378-379 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T8 | 420-425 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T9 | 420-425 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T10 | 420-425 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T11 | 420-425 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T12 | 570-575 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
| T13 | 589-590 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T14 | 754-755 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T15 | 848-849 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T16 | 891-897 | http://www.ebi.ac.uk/efo/EFO_0000265 | denotes | aortic |
| T17 | 923-924 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T18 | 931-937 | http://www.ebi.ac.uk/efo/EFO_0000265 | denotes | aortic |
| T19 | 938-943 | http://www.ebi.ac.uk/efo/EFO_0000825 | denotes | valve |
| T20 | 960-966 | http://www.ebi.ac.uk/efo/EFO_0000265 | denotes | aortic |
| T21 | 988-991 | http://purl.obolibrary.org/obo/CLO_0002755 | denotes | D–F |
| T22 | 1109-1114 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | chest |
| T23 | 1264-1269 | http://purl.obolibrary.org/obo/UBERON_0000948 | denotes | heart |
| T24 | 1264-1269 | http://purl.obolibrary.org/obo/UBERON_0007100 | denotes | heart |
| T25 | 1264-1269 | http://purl.obolibrary.org/obo/UBERON_0015228 | denotes | heart |
| T26 | 1264-1269 | http://www.ebi.ac.uk/efo/EFO_0000815 | denotes | heart |
| T27 | 1316-1324 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T28 | 1366-1376 | http://purl.obolibrary.org/obo/CHEBI_33568 | denotes | adrenaline |
| T29 | 1452-1455 | http://purl.obolibrary.org/obo/PR_000001343 | denotes | aim |
| T30 | 1482-1483 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 2 | 31-39 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 3 | 74-96 | Disease | denotes | infective endocarditis | MESH:D004696 |
| 15 | 717-723 | Chemical | denotes | oxygen | MESH:D010100 |
| 16 | 146-167 | Disease | denotes | bicuspid aortic valve | MESH:C562388 |
| 17 | 173-191 | Disease | denotes | aortic coarctation | MESH:D001017 |
| 18 | 238-246 | Disease | denotes | vomiting | MESH:D014839 |
| 19 | 248-257 | Disease | denotes | diarrhoea | MESH:D003967 |
| 20 | 269-274 | Disease | denotes | fever | MESH:D005334 |
| 21 | 287-292 | Disease | denotes | cough | MESH:D003371 |
| 22 | 551-568 | Disease | denotes | sinus tachycardia | MESH:D013616 |
| 23 | 644-661 | Disease | denotes | COVID pneumonitis | MESH:C000657245 |
| 24 | 787-814 | Disease | denotes | atrioventricular (AV) block | MESH:D054537 |
| 25 | 831-840 | Disease | denotes | ischaemia | MESH:D007511 |
| 34 | 1237-1244 | Species | denotes | patient | Tax:9606 |
| 35 | 1366-1376 | Chemical | denotes | adrenaline | MESH:D004837 |
| 36 | 891-911 | Disease | denotes | aortic regurgitation | MESH:D001022 |
| 37 | 1037-1057 | Disease | denotes | systolic dysfunction | MESH:D006331 |
| 38 | 1186-1194 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 39 | 1195-1206 | Disease | denotes | pneumonitis | MESH:D011014 |
| 40 | 1264-1275 | Disease | denotes | heart block | MESH:D006327 |
| 41 | 1343-1351 | Disease | denotes | asystole | MESH:D006323 |
| 45 | 1505-1513 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 46 | 1598-1620 | Disease | denotes | infective endocarditis | MESH:D004696 |
| 47 | 1646-1655 | Disease | denotes | infection | MESH:D007239 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 74-96 | Phenotype | denotes | infective endocarditis | http://purl.obolibrary.org/obo/HP_0006689 |
| T2 | 146-167 | Phenotype | denotes | bicuspid aortic valve | http://purl.obolibrary.org/obo/HP_0001647 |
| T3 | 173-191 | Phenotype | denotes | aortic coarctation | http://purl.obolibrary.org/obo/HP_0001680 |
| T4 | 238-246 | Phenotype | denotes | vomiting | http://purl.obolibrary.org/obo/HP_0002013 |
| T5 | 248-257 | Phenotype | denotes | diarrhoea | http://purl.obolibrary.org/obo/HP_0002014 |
| T6 | 259-274 | Phenotype | denotes | low grade fever | http://purl.obolibrary.org/obo/HP_0011134 |
| T7 | 276-292 | Phenotype | denotes | productive cough | http://purl.obolibrary.org/obo/HP_0031245 |
| T8 | 353-361 | Phenotype | denotes | crackles | http://purl.obolibrary.org/obo/HP_0030830 |
| T9 | 551-568 | Phenotype | denotes | sinus tachycardia | http://purl.obolibrary.org/obo/HP_0011703 |
| T10 | 741-752 | Phenotype | denotes | haemoptysis | http://purl.obolibrary.org/obo/HP_0002105 |
| T11 | 891-911 | Phenotype | denotes | aortic regurgitation | http://purl.obolibrary.org/obo/HP_0001659 |
| T12 | 972-979 | Phenotype | denotes | abscess | http://purl.obolibrary.org/obo/HP_0025615 |
| T13 | 1255-1275 | Phenotype | denotes | complete heart block | http://purl.obolibrary.org/obo/HP_0001709 |
| T14 | 1598-1620 | Phenotype | denotes | infective endocarditis | http://purl.obolibrary.org/obo/HP_0006689 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-115 | Sentence | denotes | Collateral implications of the COVID-19 pandemic: belated presentation of infective endocarditis in a young patient |
| T2 | 117-325 | Sentence | denotes | A 20-year-old man with known bicuspid aortic valve, and aortic coarctation repair in childhood presented with 4 weeks of vomiting, diarrhoea, low grade fever, productive cough, and progressive breathlessness. |
| T3 | 326-426 | Sentence | denotes | Auscultation revealed fine crackles bilaterally and a loud systolic murmur at the base of the heart. |
| T4 | 427-526 | Sentence | denotes | Inflammatory markers and troponin were elevated (troponin T 388 ng/L; cut-off for normal <14 ng/L). |
| T5 | 527-569 | Sentence | denotes | Initial ECG showed only sinus tachycardia. |
| T6 | 570-662 | Sentence | denotes | Chest X-ray (Panel A) showed bilateral airspace infiltrates suspicious of COVID pneumonitis. |
| T7 | 663-753 | Sentence | denotes | Shortly after admission, he deteriorated, with rising oxygen requirements and haemoptysis. |
| T8 | 754-851 | Sentence | denotes | A repeat ECG showed first-degree atrioventricular (AV) block with widespread ischaemia (Panel B). |
| T9 | 852-993 | Sentence | denotes | Bedside echocardiogram revealed severe aortic regurgitation (Panel C), a large aortic valve vegetation, and aortic root abscess (Panels D–F). |
| T10 | 994-1094 | Sentence | denotes | The left ventricle was dilated with severe systolic dysfunction, and the right ventricle was normal. |
| T11 | 1095-1207 | Sentence | denotes | Incomplete CT chest (Panel G) showed bilateral multilobular consolidation, not typical for COVID-19 pneumonitis. |
| T12 | 1208-1433 | Sentence | denotes | While in the CT scanner, the patient developed complete heart block deteriorating into pulseless electrical activity (PEA) followed by asystole refractory to adrenaline and both transcutaneous and transvenous pacing attempts. |
| T13 | 1434-1656 | Sentence | denotes | With this case we aim to emphasize that even in a pandemic period like COVID-19, it is prudent to seek medical help especially for those at high risk of developing infective endocarditis and who have symptoms of infection. |
| T14 | 1657-1734 | Sentence | denotes | Timely presentation is essential as any delay can lead to fatal consequences. |
| T15 | 1735-1756 | Sentence | denotes | Conflict of interest: |
| T16 | 1757-1866 | Sentence | denotes | The authors have submitted their declaration which can be found in the article Supplementary Material online. |
| T17 | 1868-1890 | Sentence | denotes | Supplementary Material |
| T18 | 1891-1955 | Sentence | denotes | ehaa633_Supplementary_Data Click here for additional data file. |