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PMC:7499532 / 155-1275 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 32-34 Body_part denotes AG http://purl.org/sig/ont/fma/fma61898
T2 232-234 Body_part denotes AG http://purl.org/sig/ont/fma/fma61898

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T2 165-173 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T3 176-185 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T4 190-198 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 352-360 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 390-398 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T7 734-742 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T8 805-813 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T9 904-912 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T3 113-114 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 350-351 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 483-484 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T6 651-656 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T7 803-804 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T8 857-862 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T9 941-942 http://purl.obolibrary.org/obo/CLO_0001020 denotes A

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
9 390-400 Species denotes SARS-CoV-2 Tax:2697049
10 734-744 Species denotes SARS-CoV-2 Tax:2697049
11 904-914 Species denotes SARS-CoV-2 Tax:2697049
12 165-185 Disease denotes SARS-CoV-2 infection MESH:C000657245
13 190-198 Disease denotes COVID-19 MESH:C000657245
14 352-360 Disease denotes COVID-19 MESH:C000657245
15 805-813 Disease denotes COVID-19 MESH:C000657245

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T4 0-227 Sentence denotes WHO convened an Advisory Group (AG) to consider the feasibility, potential value and limitations of establishing a closely-monitored challenge model of experimental SARS-CoV-2 infection and COVID-19 in healthy adult volunteers.
T5 228-307 Sentence denotes The AG included experts in design, establishment and performance of challenges.
T6 308-802 Sentence denotes This report summarizes issues that render a COVID-19 model daunting to establish (SARS-CoV-2’s potential to cause severe/fatal illness, its high transmissibility, and lack of a “rescue treatment” to prevent progression from mild/moderate to severe clinical illness) and it proffers prudent strategies for stepwise model development, challenge virus selection, guidelines for manufacturing challenge doses, and ways to contain SARS-CoV-2 and prevent transmission to household/community contacts.
T7 803-940 Sentence denotes A COVID-19 model could demonstrate protection against virus shedding and/or illness induced by prior SARS-CoV-2 challenge or vaccination.
T8 941-1120 Sentence denotes A limitation of the model is that vaccine efficacy in experimentally challenged healthy young adults cannot per se be extrapolated to predict efficacy in elderly/high-risk adults.