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PMC:7499529 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 974-978 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T2 1003-1007 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T3 1090-1094 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T4 1291-1295 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1708-1713 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 87-95 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T2 135-182 Disease denotes Severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T3 184-192 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T4 219-227 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T5 380-388 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T6 749-757 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T7 1437-1445 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T8 1589-1597 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 96-103 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T2 201-206 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T3 368-375 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T4 389-392 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T5 457-464 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T6 535-536 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T7 577-578 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T8 664-665 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 764-769 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T10 771-772 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 797-800 http://purl.obolibrary.org/obo/CL_0000990 denotes CDC
T12 974-978 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T13 1003-1007 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T14 1023-1026 http://purl.obolibrary.org/obo/CL_0000990 denotes CDC
T15 1090-1094 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T16 1291-1295 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T17 1567-1574 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T18 1631-1638 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1 87-95 Disease denotes COVID-19 MESH:C000657245
6 135-182 Species denotes Severe acute respiratory syndrome coronavirus 2 Tax:2697049
7 184-194 Species denotes SARS-CoV-2 Tax:2697049
8 219-227 Disease denotes COVID-19 MESH:C000657245
9 380-388 Disease denotes COVID-19 MESH:C000657245
12 696-704 Species denotes patients Tax:9606
13 749-759 Species denotes SARS-CoV-2 Tax:2697049
16 995-1002 Gene denotes RNase P
17 1437-1445 Disease denotes COVID-19 MESH:C000657245
19 1589-1599 Species denotes SARS-CoV-2 Tax:2697049

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 289-302 http://purl.obolibrary.org/obo/GO_0003968 denotes Transcriptase
T2 289-302 http://purl.obolibrary.org/obo/GO_0003899 denotes Transcriptase
T3 819-832 http://purl.obolibrary.org/obo/GO_0003968 denotes Transcriptase
T4 819-832 http://purl.obolibrary.org/obo/GO_0003899 denotes Transcriptase
T5 995-1002 http://purl.obolibrary.org/obo/GO_0004526 denotes RNase P
T6 1135-1142 http://purl.obolibrary.org/obo/GO_0004526 denotes RNase P

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-103 Sentence denotes 3D Printed Alternative to the Standard Synthetic Flocked Nasopharyngeal Swabs Used for COVID-19 testing
T2 105-113 Sentence denotes Abstract
T3 114-122 Sentence denotes Abstract
T4 124-134 Sentence denotes Background
T5 135-339 Sentence denotes Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19, can be detected in respiratory samples by Real-time Reverse Transcriptase (RT)-PCR or other molecular methods.
T6 340-512 Sentence denotes Accessibility of diagnostic testing for COVID-19 has been limited by intermittent shortages of supplies required for testing, including flocked nasopharyngeal (FLNP) swabs.
T7 514-521 Sentence denotes Methods
T8 522-608 Sentence denotes We developed a 3D-printed nasopharyngeal (3DP) swab as a replacement of the FLNP swab.
T9 609-921 Sentence denotes The performance of 3DP and FLNP swabs were compared in a clinical trial of symptomatic patients at three clinical sites (n=291) using three SARS-CoV-2 EUA tests: a modified version of the CDC Real-time Reverse Transcriptase (RT)-PCR Diagnostic Panel and two commercial automated formats, Roche Cobas and NeuMoDx.
T10 923-930 Sentence denotes Results
T11 931-1211 Sentence denotes The cycle threshold (C(t)) values from the gene targets and the RNase P gene control in the CDC assay showed no significant differences between swabs for both gene targets (p=0.152 and p=0.092), with the RNase P target performing significantly better in the 3DP swabs (p & 0.001).
T12 1212-1400 Sentence denotes The C(t) values showed no significant differences between swabs for both viral gene targets in the Roche cobas assay (p=0.05 and p=0.05) as well as the NeuMoDx assay (p=0.401 and p=0.484).
T13 1401-1501 Sentence denotes The overall clinical correlation of COVID-19 diagnosis between all methods was 95.88% (Kappa 0.901).
T14 1503-1514 Sentence denotes Conclusions
T15 1515-1600 Sentence denotes 3DP swabs were equivalent to standard FLNP in three testing platforms for SARS-CoV-2.
T16 1601-1810 Sentence denotes Given the need for widespread testing, 3DP swabs printed on-site are an alternate to FLNP that can rapidly scale in response to acute needs when supply chain disruptions affect availability of collection kits.