PMC:7497282 / 48975-50253 JSONTXT

{"project":"MyTest","denotations":[{"id":"32741232-28687986-29927094","span":{"begin":254,"end":256},"obj":"28687986"},{"id":"32741232-28838198-29927095","span":{"begin":449,"end":451},"obj":"28838198"},{"id":"32741232-24472313-29927096","span":{"begin":494,"end":496},"obj":"24472313"},{"id":"32741232-25316861-29927097","span":{"begin":498,"end":500},"obj":"25316861"},{"id":"32741232-25316863-29927098","span":{"begin":502,"end":504},"obj":"25316863"},{"id":"32741232-25316864-29927099","span":{"begin":506,"end":508},"obj":"25316864"},{"id":"32741232-25505296-29927100","span":{"begin":510,"end":512},"obj":"25505296"},{"id":"32741232-28838194-29927101","span":{"begin":743,"end":745},"obj":"28838194"},{"id":"32741232-30839913-29927102","span":{"begin":868,"end":870},"obj":"30839913"},{"id":"32741232-17184393-29927103","span":{"begin":1108,"end":1110},"obj":"17184393"},{"id":"32741232-26404632-29927104","span":{"begin":1112,"end":1114},"obj":"26404632"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"Recognizing the increasing role of environmental surveillance for polioviruses, KRI systematically reviewed published poliovirus environmental surveillance studies and reported information related to the design, cost, and effectiveness of these systems [67]. KRI also explored the dynamics of die-out of serotype 2 polioviruses after homotypic OPV cessation and lessons learned from its cessation relevant to the cessation of OPV serotypes 1 and 3 [68]. Reviewing insights from prior modeling [35, 36, 40, 41, 43], KRI demonstrated how under-vaccinated subpopulations can sustain poliovirus transmission despite high coverage in the surrounding population, depending on the degree of mixing and the size of the under-vaccinated subpopulation [69]. Building on these lessons, KRI explored the potential for silent circulation of live polioviruses in small populations [70], and the role of hard-to-reach subpopulations in characterizing the confidence about the absence of transmission for purposes of certifying the eradication of WPV1 [71]. KRI revisited its earlier characterizations of containment risks [13, 51] and explored current containment risks and their management [72]. KRI also discussed the role of system dynamics in integrated polio risk management modeling [4]."}

{"project":"2_test","denotations":[{"id":"32741232-28687986-29927094","span":{"begin":254,"end":256},"obj":"28687986"},{"id":"32741232-28838198-29927095","span":{"begin":449,"end":451},"obj":"28838198"},{"id":"32741232-24472313-29927096","span":{"begin":494,"end":496},"obj":"24472313"},{"id":"32741232-25316861-29927097","span":{"begin":498,"end":500},"obj":"25316861"},{"id":"32741232-25316863-29927098","span":{"begin":502,"end":504},"obj":"25316863"},{"id":"32741232-25316864-29927099","span":{"begin":506,"end":508},"obj":"25316864"},{"id":"32741232-25505296-29927100","span":{"begin":510,"end":512},"obj":"25505296"},{"id":"32741232-28838194-29927101","span":{"begin":743,"end":745},"obj":"28838194"},{"id":"32741232-30839913-29927102","span":{"begin":868,"end":870},"obj":"30839913"},{"id":"32741232-17184393-29927103","span":{"begin":1108,"end":1110},"obj":"17184393"},{"id":"32741232-26404632-29927104","span":{"begin":1112,"end":1114},"obj":"26404632"}],"text":"Recognizing the increasing role of environmental surveillance for polioviruses, KRI systematically reviewed published poliovirus environmental surveillance studies and reported information related to the design, cost, and effectiveness of these systems [67]. KRI also explored the dynamics of die-out of serotype 2 polioviruses after homotypic OPV cessation and lessons learned from its cessation relevant to the cessation of OPV serotypes 1 and 3 [68]. Reviewing insights from prior modeling [35, 36, 40, 41, 43], KRI demonstrated how under-vaccinated subpopulations can sustain poliovirus transmission despite high coverage in the surrounding population, depending on the degree of mixing and the size of the under-vaccinated subpopulation [69]. Building on these lessons, KRI explored the potential for silent circulation of live polioviruses in small populations [70], and the role of hard-to-reach subpopulations in characterizing the confidence about the absence of transmission for purposes of certifying the eradication of WPV1 [71]. KRI revisited its earlier characterizations of containment risks [13, 51] and explored current containment risks and their management [72]. KRI also discussed the role of system dynamics in integrated polio risk management modeling [4]."}