PMC:7473770 / 40979-42287 JSONTXT

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The tissue volume V is given by the sum of all voxels containing tissue. The surface area SA is defined by all tissue voxels with a distance of 1 pixel to the air. From this information we calculated the specific surface(2) SV=SA/Vwith S⁢A/V surface area volume -ratio. Further a characteristic length(3) Lc=V/SA⋅vxwith v⁢x edge length of a voxel was determined for each sample. Additionally, the mean distance (dO2¯) from all tissue voxels to the closest air compartment and its standard deviation was 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