PMC:7473478 / 2547-3760
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T27 | 17-30 | Body_part | denotes | IMMUNE SYSTEM | http://purl.org/sig/ont/fma/fma9825 |
| T28 | 199-205 | Body_part | denotes | plasma | http://purl.org/sig/ont/fma/fma62970 |
| T29 | 216-220 | Body_part | denotes | IL-1 | http://purl.org/sig/ont/fma/fma86583 |
| T30 | 257-265 | Body_part | denotes | monocyte | http://purl.org/sig/ont/fma/fma62864 |
| T31 | 300-310 | Body_part | denotes | macrophage | http://purl.org/sig/ont/fma/fma63261 |
| T32 | 324-331 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
| T33 | 352-355 | Body_part | denotes | CSF | http://purl.org/sig/ont/fma/fma20935 |
| T34 | 541-546 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T35 | 551-559 | Body_part | denotes | NK cells | http://purl.org/sig/ont/fma/fma63147 |
| T36 | 554-559 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T37 | 622-627 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T38 | 643-656 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
| T39 | 681-695 | Body_part | denotes | helper T cells | http://purl.org/sig/ont/fma/fma70572 |
| T40 | 690-695 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T41 | 721-726 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T42 | 732-750 | Body_part | denotes | regulatory T cells | http://purl.org/sig/ont/fma/fma84070 |
| T43 | 745-750 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T44 | 864-882 | Body_part | denotes | regulatory T cells | http://purl.org/sig/ont/fma/fma84070 |
| T45 | 877-882 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T46 | 1015-1020 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T47 | 1044-1049 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T48 | 1122-1127 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T4 | 643-656 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T20 | 0-8 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T21 | 143-151 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T22 | 183-191 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T23 | 582-590 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T24 | 783-791 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T25 | 931-943 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
| T26 | 1202-1210 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T24 | 17-30 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | IMMUNE SYSTEM |
| T25 | 199-205 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
| T26 | 237-241 | http://purl.obolibrary.org/obo/CLO_0053704 | denotes | IL-8 |
| T27 | 257-265 | http://purl.obolibrary.org/obo/CL_0000576 | denotes | monocyte |
| T28 | 283-290 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
| T29 | 350-355 | http://purl.obolibrary.org/obo/PR_000005932 | denotes | G-CSF |
| T30 | 539-546 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T31 | 551-559 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | NK cells |
| T32 | 622-627 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T33 | 643-656 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
| T34 | 681-695 | http://purl.obolibrary.org/obo/CL_0000912 | denotes | helper T cells |
| T35 | 719-726 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T36 | 732-750 | http://purl.obolibrary.org/obo/CL_0000815 | denotes | regulatory T cells |
| T37 | 864-882 | http://purl.obolibrary.org/obo/CL_0000815 | denotes | regulatory T cells |
| T38 | 945-947 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T39 | 966-967 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T40 | 1007-1020 | http://purl.obolibrary.org/obo/CL_0000898 | denotes | naïve T cells |
| T41 | 1042-1049 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
| T42 | 1122-1127 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T43 | 1135-1136 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T3 | 216-218 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T5 | 223-225 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T7 | 231-233 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T9 | 237-239 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T11 | 243-245 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
| T13 | 283-290 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
| T14 | 292-295 | Chemical | denotes | MCP | http://purl.obolibrary.org/obo/CHEBI_132592|http://purl.obolibrary.org/obo/CHEBI_50099 |
| T16 | 324-331 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 41 | 0-8 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 68 | 216-221 | Gene | denotes | IL-1β | Gene:3552 |
| 69 | 223-229 | Gene | denotes | IL-1RA | Gene:3557 |
| 70 | 231-235 | Gene | denotes | IL-7 | Gene:3574 |
| 71 | 237-241 | Gene | denotes | IL-8 | Gene:3576 |
| 72 | 243-248 | Gene | denotes | IL-10 | Gene:3586 |
| 73 | 250-255 | Gene | denotes | IFN-γ | Gene:3458 |
| 74 | 257-298 | Gene | denotes | monocyte chemoattrac-tant peptide (MCP)-1 | Gene:6347 |
| 75 | 300-340 | Gene | denotes | macrophage inflammatory protein (MIP)-1A | Gene:6348 |
| 76 | 342-348 | Gene | denotes | MIP-1B | Gene:6351 |
| 77 | 350-355 | Gene | denotes | G-CSF | Gene:1440 |
| 78 | 361-366 | Gene | denotes | TNF-α | Gene:7124 |
| 79 | 1137-1141 | Gene | denotes | plau | Gene:5328 |
| 80 | 160-168 | Species | denotes | patients | Tax:9606 |
| 81 | 183-193 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 82 | 460-468 | Species | denotes | patients | Tax:9606 |
| 83 | 591-599 | Species | denotes | patients | Tax:9606 |
| 84 | 769-777 | Species | denotes | patients | Tax:9606 |
| 85 | 1074-1082 | Species | denotes | patients | Tax:9606 |
| 86 | 1202-1212 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 87 | 143-151 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 88 | 169-177 | Disease | denotes | infected | MESH:D007239 |
| 89 | 582-590 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 90 | 783-791 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 91 | 931-943 | Disease | denotes | inflammation | MESH:D007249 |
| 92 | 1035-1043 | Disease | denotes | memory T | MESH:D008569 |
| 93 | 1065-1073 | Disease | denotes | infected | MESH:D007239 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T5 | 223-229 | http://purl.obolibrary.org/obo/GO_0005152 | denotes | IL-1RA |
| T6 | 931-943 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
| T7 | 1035-1041 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | memory |
| T8 | 1115-1121 | http://purl.obolibrary.org/obo/GO_0007613 | denotes | memory |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T21 | 0-30 | Sentence | denotes | COVID-19 AND THE IMMUNE SYSTEM |
| T22 | 31-156 | Sentence | denotes | The dynamic equilibrium maintained by innate and adaptive immunity is essential for impeding the progression of COVID-19 (7). |
| T23 | 157-409 | Sentence | denotes | In patients infected with SARS-CoV-2, the plasma levels of IL-1β, IL-1RA, IL-7, IL-8, IL-10, IFN-γ, monocyte chemoattrac-tant peptide (MCP)-1, macrophage inflammatory protein (MIP)-1A, MIP-1B, G-CSF, and TNF-α are significantly higher than in controls. |
| T24 | 410-499 | Sentence | denotes | The levels of these factors are also increased in patients who were admitted to ICUs (8). |
| T25 | 500-604 | Sentence | denotes | Similarly, reductions in the levels of T cells and NK cells have been observed in COVID-19 patients (9). |
| T26 | 605-662 | Sentence | denotes | The loss of such cells can impair the immune system (10). |
| T27 | 663-843 | Sentence | denotes | The levels of the helper T cells, cytotoxic suppressive T cells, and regulatory T cells are much lower in patients with COVID-19 than in their healthy and less severe counterparts. |
| T28 | 844-949 | Sentence | denotes | The decrease in the regulatory T cells may hamper their ability to inhibit the chronic inflammation (11). |
| T29 | 950-1088 | Sentence | denotes | Interes-tingly, a remarkable increase is observed in the naïve T cells, where as the memory T cells are reduced in infected patients (10). |
| T30 | 1089-1213 | Sentence | denotes | The reduced expression of memory cells may be a plau-sible explanation for the increased rates of reinfection by SARS-CoV-2. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32731913-31981224-8028458 | 153-154 | 31981224 | denotes | 7 |
| 32731913-32161940-8028459 | 496-497 | 32161940 | denotes | 8 |
| 32731913-32299202-8028460 | 658-660 | 32299202 | denotes | 10 |
| 32731913-20559327-8028461 | 945-947 | 20559327 | denotes | 11 |
| 32731913-32299202-8028462 | 1084-1086 | 32299202 | denotes | 10 |