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PMC:7464116 / 29699-30744 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T196 171-177 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T197 343-349 Body_part denotes muscle http://purl.org/sig/ont/fma/fma32558
T198 367-373 Body_part denotes kidney http://purl.org/sig/ont/fma/fma7203
T199 643-648 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T200 854-868 Body_part denotes muscle, tissue http://purl.org/sig/ont/fma/fma9641

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T81 171-177 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T82 367-373 Body_part denotes kidney http://purl.obolibrary.org/obo/UBERON_0002113
T83 854-868 Body_part denotes muscle, tissue http://purl.obolibrary.org/obo/UBERON_0002385
T84 862-868 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T324 91-99 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T325 269-283 Disease denotes rhabdomyolysis http://purl.obolibrary.org/obo/MONDO_0005290
T326 288-302 Disease denotes rhabdomyolysis http://purl.obolibrary.org/obo/MONDO_0005290
T327 676-698 Disease denotes acute tubular necrosis http://purl.obolibrary.org/obo/MONDO_0006637
T328 705-719 Disease denotes Rhabdomyolysis http://purl.obolibrary.org/obo/MONDO_0005290
T329 723-731 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T330 836-844 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T331 836-840 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T332 953-961 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T333 983-997 Disease denotes rhabdomyolysis http://purl.obolibrary.org/obo/MONDO_0005290
T334 1041-1044 Disease denotes AKI http://purl.obolibrary.org/obo/MONDO_0002492

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T426 46-47 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T427 132-133 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T428 171-177 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T429 171-177 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T430 171-177 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T431 326-335 http://purl.obolibrary.org/obo/PR_000010213 denotes myoglobin
T432 343-349 http://purl.obolibrary.org/obo/UBERON_0001630 denotes muscle
T433 343-349 http://purl.obolibrary.org/obo/UBERON_0005090 denotes muscle
T434 343-349 http://www.ebi.ac.uk/efo/EFO_0000801 denotes muscle
T435 343-349 http://www.ebi.ac.uk/efo/EFO_0001949 denotes muscle
T436 367-373 http://purl.obolibrary.org/obo/UBERON_0002113 denotes kidney
T437 367-373 http://www.ebi.ac.uk/efo/EFO_0000927 denotes kidney
T438 367-373 http://www.ebi.ac.uk/efo/EFO_0000929 denotes kidney
T439 387-396 http://purl.obolibrary.org/obo/PR_000010213 denotes Myoglobin
T440 643-648 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T441 807-808 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T442 854-868 http://purl.obolibrary.org/obo/UBERON_0002385 denotes muscle, tissue

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T78 229-237 Chemical denotes creatine http://purl.obolibrary.org/obo/CHEBI_16919|http://purl.obolibrary.org/obo/CHEBI_57947
T80 326-335 Chemical denotes myoglobin http://purl.obolibrary.org/obo/CHEBI_7044
T81 387-396 Chemical denotes Myoglobin http://purl.obolibrary.org/obo/CHEBI_7044
T82 560-572 Chemical denotes nitric oxide http://purl.obolibrary.org/obo/CHEBI_16480
T83 567-572 Chemical denotes oxide http://purl.obolibrary.org/obo/CHEBI_25741|http://purl.obolibrary.org/obo/CHEBI_29356
T85 912-916 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T56 466-482 http://purl.obolibrary.org/obo/GO_0042310 denotes vasoconstriction
T57 599-608 http://purl.obolibrary.org/obo/GO_0009058 denotes formation
T58 690-698 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T59 690-698 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T60 690-698 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T61 690-698 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T62 1025-1037 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T180 0-113 Sentence denotes In the most recent studies, the hypothesis of a multifactorial etiology of renal damage in COVID-19 is confirmed.
T181 114-284 Sentence denotes Su et al. [66] in a study performed by analyzing autopsy kidney samples showed pigmented casts with high levels of creatine phosphokinase, attributable to rhabdomyolysis.
T182 285-386 Sentence denotes In rhabdomyolysis the massive release of myoglobin due to muscle damage can cause kidney dysfunction.
T183 387-649 Sentence denotes Myoglobin, in fact, shows its renal toxicity through various mechanisms: renal vasoconstriction related to the hyperactivation of RASS by hypoperfusion and the reduction of nitric oxide levels; intratubular cast formation; direct toxicity on renal tubular cells.
T184 650-704 Sentence denotes These processes result in acute tubular necrosis [78].
T185 705-774 Sentence denotes Rhabdomyolysis in COVID-19 patients is hypothetically multifactorial.
T186 775-937 Sentence denotes In fact, it may be secondary to a direct cytotoxic effect of SARS-CoV-2 on the muscle, tissue hypoxia due to hyperventilation or also to drug-induced damage [66].
T187 938-1045 Sentence denotes Presumably, in COVID-19 patients who develop rhabdomyolysis, it may participate in the pathogenesis of AKI.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T100 269-283 Phenotype denotes rhabdomyolysis http://purl.obolibrary.org/obo/HP_0003201
T101 288-302 Phenotype denotes rhabdomyolysis http://purl.obolibrary.org/obo/HP_0003201
T102 676-698 Phenotype denotes acute tubular necrosis http://purl.obolibrary.org/obo/HP_0008682
T103 705-719 Phenotype denotes Rhabdomyolysis http://purl.obolibrary.org/obo/HP_0003201
T104 869-876 Phenotype denotes hypoxia http://purl.obolibrary.org/obo/HP_0012418
T105 884-900 Phenotype denotes hyperventilation http://purl.obolibrary.org/obo/HP_0002883
T106 983-997 Phenotype denotes rhabdomyolysis http://purl.obolibrary.org/obo/HP_0003201
T107 1041-1044 Phenotype denotes AKI http://purl.obolibrary.org/obo/HP_0001919

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
909 387-396 Gene denotes Myoglobin Gene:4151
910 326-335 Gene denotes myoglobin Gene:4151
911 732-740 Species denotes patients Tax:9606
912 836-846 Species denotes SARS-CoV-2 Tax:2697049
913 962-970 Species denotes patients Tax:9606
914 229-237 Chemical denotes creatine MESH:D003401
915 560-572 Chemical denotes nitric oxide MESH:D009569
916 75-87 Disease denotes renal damage MESH:D007674
917 91-99 Disease denotes COVID-19 MESH:C000657245
918 193-202 Disease denotes pigmented MESH:D010859
919 269-283 Disease denotes rhabdomyolysis MESH:D012206
920 288-302 Disease denotes rhabdomyolysis MESH:D012206
921 343-356 Disease denotes muscle damage MESH:D009135
922 367-385 Disease denotes kidney dysfunction MESH:D007674
923 423-431 Disease denotes toxicity MESH:D064420
924 617-625 Disease denotes toxicity MESH:D064420
925 676-698 Disease denotes acute tubular necrosis MESH:D007683
926 705-719 Disease denotes Rhabdomyolysis MESH:D012206
927 723-731 Disease denotes COVID-19 MESH:C000657245
928 869-876 Disease denotes hypoxia MESH:D000860
929 884-900 Disease denotes hyperventilation MESH:D006985
930 953-961 Disease denotes COVID-19 MESH:C000657245
931 983-997 Disease denotes rhabdomyolysis MESH:D012206

2_test

Id Subject Object Predicate Lexical cue
32759645-32327202-58096207 125-127 32327202 denotes 66
32759645-32327202-58096208 933-935 32327202 denotes 66