PMC:7464116 / 1475-4523
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T8 | 2445-2453 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
| T9 | 2492-2498 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T10 | 2569-2575 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T11 | 2698-2704 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
| T12 | 2985-2991 | Body_part | denotes | kidney | http://purl.org/sig/ont/fma/fma7203 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T7 | 2492-2498 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T8 | 2569-2575 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T9 | 2698-2704 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T10 | 2985-2991 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T32 | 51-60 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T33 | 267-314 | Disease | denotes | severe acute respiratory syndrome-coronavirus-2 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T34 | 267-300 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T35 | 316-324 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T36 | 316-320 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T37 | 393-426 | Disease | denotes | severe acute respiratory syndrome | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T38 | 428-432 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T39 | 507-515 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T40 | 507-511 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T41 | 559-583 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T42 | 588-596 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T43 | 795-803 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T44 | 1740-1748 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T45 | 1987-1990 | Disease | denotes | flu | http://purl.obolibrary.org/obo/MONDO_0005812 |
| T46 | 2063-2071 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T47 | 2156-2165 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
| T48 | 2192-2211 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
| T49 | 2268-2290 | Disease | denotes | venous thromboembolism | http://purl.obolibrary.org/obo/MONDO_0005399 |
| T50 | 2292-2295 | Disease | denotes | VTE | http://purl.obolibrary.org/obo/MONDO_0005399 |
| T51 | 2307-2313 | Disease | denotes | stroke | http://purl.obolibrary.org/obo/MONDO_0005098|http://purl.obolibrary.org/obo/MONDO_0011057 |
| T53 | 2318-2341 | Disease | denotes | acute coronary syndrome | http://purl.obolibrary.org/obo/MONDO_0005542 |
| T54 | 2348-2369 | Disease | denotes | myocardial infarction | http://purl.obolibrary.org/obo/MONDO_0005068 |
| T55 | 2424-2432 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T56 | 2465-2490 | Disease | denotes | acute respiratory failure | http://purl.obolibrary.org/obo/MONDO_0001208|http://purl.obolibrary.org/obo/MONDO_0021113 |
| T58 | 2563-2582 | Disease | denotes | acute kidney injury | http://purl.obolibrary.org/obo/MONDO_0002492 |
| T59 | 2576-2582 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T60 | 2584-2587 | Disease | denotes | AKI | http://purl.obolibrary.org/obo/MONDO_0002492 |
| T61 | 2613-2621 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T62 | 2613-2617 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T63 | 2690-2712 | Disease | denotes | chronic kidney disease | http://purl.obolibrary.org/obo/MONDO_0005300 |
| T64 | 2698-2712 | Disease | denotes | kidney disease | http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240 |
| T66 | 2714-2717 | Disease | denotes | CKD | http://purl.obolibrary.org/obo/MONDO_0005300 |
| T67 | 2763-2771 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T68 | 2860-2868 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
| T69 | 2869-2878 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T70 | 2985-3000 | Disease | denotes | kidney diseases | http://purl.obolibrary.org/obo/MONDO_0001343|http://purl.obolibrary.org/obo/MONDO_0005240 |
| T72 | 3021-3029 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T26 | 183-195 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | Organization |
| T27 | 240-241 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T28 | 478-485 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T29 | 743-744 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T30 | 1386-1389 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T31 | 1458-1461 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T32 | 1471-1472 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T33 | 1576-1581 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T34 | 1590-1593 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T35 | 1676-1679 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T36 | 1738-1739 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T37 | 1765-1768 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T38 | 1835-1836 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T39 | 1985-1986 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T40 | 2022-2025 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T41 | 2171-2172 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T42 | 2371-2373 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T43 | 2492-2498 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
| T44 | 2492-2498 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
| T45 | 2492-2498 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
| T46 | 2510-2513 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T47 | 2569-2575 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
| T48 | 2569-2575 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
| T49 | 2569-2575 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
| T50 | 2698-2704 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
| T51 | 2698-2704 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
| T52 | 2698-2704 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
| T53 | 2720-2722 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
| T54 | 2746-2754 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney’s |
| T55 | 2746-2754 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney’s |
| T56 | 2746-2754 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney’s |
| T57 | 2806-2809 | http://purl.obolibrary.org/obo/PR_000001343 | denotes | aim |
| T58 | 2985-2991 | http://purl.obolibrary.org/obo/UBERON_0002113 | denotes | kidney |
| T59 | 2985-2991 | http://www.ebi.ac.uk/efo/EFO_0000927 | denotes | kidney |
| T60 | 2985-2991 | http://www.ebi.ac.uk/efo/EFO_0000929 | denotes | kidney |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T11 | 0-2 | Sentence | denotes | 1. |
| T12 | 3-15 | Sentence | denotes | Introduction |
| T13 | 16-143 | Sentence | denotes | By December 2019, unusual cases of pneumonia had been reported in the city of Wuhan, located in central China’s Hubei province. |
| T14 | 144-492 | Sentence | denotes | On January 12th 2020, the World Health Organization (WHO) stated that the disease was caused by a novel coronavirus, named severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), belonging to the β-coronavirus cluster, which also includes the severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS) viruses [1,2]. |
| T15 | 493-761 | Sentence | denotes | The resulting SARS-CoV-2 related disease was defined as the novel coronavirus disease 2019, or COVID-19, that rapidly spread throughout China, followed by an increasing number of cases in all continents with the exception of Antarctica, resulting in a global pandemic. |
| T16 | 762-819 | Sentence | denotes | The data of the global burden of COVID-19 are impressive. |
| T17 | 820-1030 | Sentence | denotes | Indeed, currently (available data up to 23 July 2020) the coronavirus is affecting 212 countries and territories around the world, with over 15 million cases and over 630,000 confirmed deaths (global mortality: |
| T18 | 1031-1043 | Sentence | denotes | 5.4%) [3,4]. |
| T19 | 1044-1114 | Sentence | denotes | The Americas and Europe are the most affected continents in the world. |
| T20 | 1115-1216 | Sentence | denotes | In the United States of America (U.S.A.), 4,103,674 cases and over 146,000 deaths have been reported. |
| T21 | 1217-1345 | Sentence | denotes | In Europe, many outbreaks are steadily rising in Russia, Spain, UK and Italy, with over 200,000 overall deaths in the continent. |
| T22 | 1346-1444 | Sentence | denotes | However, in China the rate of new cases has progressively decreased substantially since March [3]. |
| T23 | 1445-1496 | Sentence | denotes | The pandemic has also had a severe economic impact. |
| T24 | 1497-1761 | Sentence | denotes | In fact, to help improve the clinical management of patients infected with the virus, Europe has mobilized more than 10 million euros from research funding and the United Kingdom has also invested £20,000,000 to allow for the development of a COVID-19 vaccine [5]. |
| T25 | 1762-2375 | Sentence | denotes | It has also been estimated that in the U.S.A., the health care costs for a single infected patient is over $3000, resulting in an overall predicted expenditure of $654.0 billion over the entire period of the pandemic [6,7].A flu-like syndrome of mild severity has been observed in most cases (80%) of COVID-19 [8,9], but in 20% of cases there have been other complications such as interstitial pneumonia with a variable degree of respiratory failure [10] as well as thromboembolic complications, including venous thromboembolism (VTE), ischemic stroke and acute coronary syndrome (ACS)/myocardial infarction [11]. |
| T26 | 2376-2624 | Sentence | denotes | Although the principal features associated with COVID-19 are diffuse alveolar damage and acute respiratory failure, kidney impairment has also often developed, with the frequent onset of acute kidney injury (AKI) in patients infected by SARS-CoV-2. |
| T27 | 2625-2724 | Sentence | denotes | In addition, more than 20% of deceased patients were affected by chronic kidney disease (CKD) [11]. |
| T28 | 2725-2801 | Sentence | denotes | For this reason, the kidney’s role in COVID-19 needs to be investigated [8]. |
| T29 | 2802-3048 | Sentence | denotes | The aim of this review is to describe the main aspects of COVID-19 infection, namely the epidemiology and pathophysiology, together with prevention strategies and the contribution of kidney diseases to the prognosis of COVID-19 affected patients. |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T12 | 51-60 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T13 | 2156-2165 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
| T14 | 2192-2211 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
| T15 | 2228-2242 | Phenotype | denotes | thromboembolic | http://purl.obolibrary.org/obo/HP_0001907 |
| T16 | 2275-2290 | Phenotype | denotes | thromboembolism | http://purl.obolibrary.org/obo/HP_0001907 |
| T17 | 2298-2313 | Phenotype | denotes | ischemic stroke | http://purl.obolibrary.org/obo/HP_0002140 |
| T18 | 2348-2369 | Phenotype | denotes | myocardial infarction | http://purl.obolibrary.org/obo/HP_0001658 |
| T19 | 2437-2460 | Phenotype | denotes | diffuse alveolar damage | http://purl.obolibrary.org/obo/HP_0033006 |
| T20 | 2471-2490 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
| T21 | 2563-2582 | Phenotype | denotes | acute kidney injury | http://purl.obolibrary.org/obo/HP_0001919 |
| T22 | 2584-2587 | Phenotype | denotes | AKI | http://purl.obolibrary.org/obo/HP_0001919 |
| T23 | 2690-2712 | Phenotype | denotes | chronic kidney disease | http://purl.obolibrary.org/obo/HP_0012622 |
| T24 | 2714-2717 | Phenotype | denotes | CKD | http://purl.obolibrary.org/obo/HP_0012622 |
| T25 | 2985-3000 | Phenotype | denotes | kidney diseases | http://purl.obolibrary.org/obo/HP_0000112 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 55 | 242-259 | Species | denotes | novel coronavirus | Tax:2697049 |
| 56 | 267-314 | Species | denotes | severe acute respiratory syndrome-coronavirus-2 | Tax:2697049 |
| 57 | 316-326 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 58 | 346-359 | Species | denotes | β-coronavirus | Tax:694002 |
| 59 | 51-60 | Disease | denotes | pneumonia | MESH:D011014 |
| 60 | 438-470 | Disease | denotes | Middle East respiratory syndrome | MESH:D018352 |
| 61 | 472-476 | Disease | denotes | MERS | MESH:D018352 |
| 65 | 507-517 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 66 | 559-583 | Disease | denotes | coronavirus disease 2019 | MESH:C000657245 |
| 67 | 588-596 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 72 | 878-889 | Species | denotes | coronavirus | Tax:11118 |
| 73 | 795-803 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 74 | 1005-1011 | Disease | denotes | deaths | MESH:D003643 |
| 75 | 1020-1029 | Disease | denotes | mortality | MESH:D003643 |
| 110 | 1549-1557 | Species | denotes | patients | Tax:9606 |
| 111 | 1625-1630 | Species | denotes | euros | Tax:9319 |
| 112 | 1853-1860 | Species | denotes | patient | Tax:9606 |
| 113 | 2592-2600 | Species | denotes | patients | Tax:9606 |
| 114 | 2613-2623 | Species | denotes | SARS-CoV-2 | Tax:2697049 |
| 115 | 2664-2672 | Species | denotes | patients | Tax:9606 |
| 116 | 3039-3047 | Species | denotes | patients | Tax:9606 |
| 117 | 1190-1196 | Disease | denotes | deaths | MESH:D003643 |
| 118 | 1321-1327 | Disease | denotes | deaths | MESH:D003643 |
| 119 | 1558-1566 | Disease | denotes | infected | MESH:D007239 |
| 120 | 1740-1748 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 121 | 1844-1852 | Disease | denotes | infected | MESH:D007239 |
| 122 | 1987-2004 | Disease | denotes | flu-like syndrome | MESH:D007251 |
| 123 | 2063-2071 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 124 | 2143-2165 | Disease | denotes | interstitial pneumonia | MESH:D009395 |
| 125 | 2192-2211 | Disease | denotes | respiratory failure | MESH:D012131 |
| 126 | 2228-2256 | Disease | denotes | thromboembolic complications | MESH:D013923 |
| 127 | 2268-2290 | Disease | denotes | venous thromboembolism | MESH:D054556 |
| 128 | 2292-2295 | Disease | denotes | VTE | MESH:D054556 |
| 129 | 2298-2341 | Disease | denotes | ischemic stroke and acute coronary syndrome | MESH:D020521 |
| 130 | 2348-2369 | Disease | denotes | myocardial infarction | MESH:D009203 |
| 131 | 2424-2432 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 132 | 2445-2460 | Disease | denotes | alveolar damage | MESH:D055370 |
| 133 | 2471-2490 | Disease | denotes | respiratory failure | MESH:D012131 |
| 134 | 2492-2509 | Disease | denotes | kidney impairment | MESH:D007674 |
| 135 | 2563-2582 | Disease | denotes | acute kidney injury | MESH:D058186 |
| 136 | 2601-2609 | Disease | denotes | infected | MESH:D007239 |
| 137 | 2690-2712 | Disease | denotes | chronic kidney disease | MESH:D051436 |
| 138 | 2714-2717 | Disease | denotes | CKD | MESH:D012080 |
| 139 | 2763-2771 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 140 | 2860-2868 | Disease | denotes | COVID-19 | MESH:C000657245 |
| 141 | 2869-2878 | Disease | denotes | infection | MESH:D007239 |
| 142 | 2985-3000 | Disease | denotes | kidney diseases | MESH:D007674 |
| 143 | 3021-3029 | Disease | denotes | COVID-19 | MESH:C000657245 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32759645-31978945-58096132 | 489-490 | 31978945 | denotes | 2 |
| 32759645-32169574-58096133 | 1758-1759 | 32169574 | denotes | 5 |
| 32759645-32335410-58096134 | 1982-1983 | 32335410 | denotes | 7 |
| 32759645-32007143-58096135 | 2075-2076 | 32007143 | denotes | 9 |
| 32759645-32236465-58096136 | 2213-2215 | 32236465 | denotes | 10 |
| 32759645-32312654-58096137 | 2371-2373 | 32312654 | denotes | 11 |
| 32759645-32312654-58096138 | 2720-2722 | 32312654 | denotes | 11 |