PMC:7463108 / 97336-97614 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T918","span":{"begin":134,"end":143},"obj":"Body_part"},{"id":"T919","span":{"begin":158,"end":162},"obj":"Body_part"},{"id":"T920","span":{"begin":202,"end":210},"obj":"Body_part"}],"attributes":[{"id":"A918","pred":"fma_id","subj":"T918","obj":"http://purl.org/sig/ont/fma/fma13889"},{"id":"A919","pred":"fma_id","subj":"T919","obj":"http://purl.org/sig/ont/fma/fma12520"},{"id":"A920","pred":"fma_id","subj":"T920","obj":"http://purl.org/sig/ont/fma/fma67238"}],"text":" effects based on “on-off” and “steady-state” drug administration schedules have been reported for the stress-responsive hypothalamic-pituitary-adrenal (HPA) axis, the endogenous opioid system, and the dopamine system (Kreek 1973; Kreek et al. 2002; George et al. 2012). Acute o"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T205","span":{"begin":134,"end":143},"obj":"Disease"}],"attributes":[{"id":"A205","pred":"mondo_id","subj":"T205","obj":"http://purl.obolibrary.org/obo/MONDO_0021156"}],"text":" effects based on “on-off” and “steady-state” drug administration schedules have been reported for the stress-responsive hypothalamic-pituitary-adrenal (HPA) axis, the endogenous opioid system, and the dopamine system (Kreek 1973; Kreek et al. 2002; George et al. 2012). Acute o"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T976","span":{"begin":202,"end":210},"obj":"http://purl.obolibrary.org/obo/CHEBI_18243"}],"text":" effects based on “on-off” and “steady-state” drug administration schedules have been reported for the stress-responsive hypothalamic-pituitary-adrenal (HPA) axis, the endogenous opioid system, and the dopamine system (Kreek 1973; Kreek et al. 2002; George et al. 2012). Acute o"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T19189","span":{"begin":46,"end":50},"obj":"Chemical"},{"id":"T97969","span":{"begin":153,"end":156},"obj":"Chemical"},{"id":"T44514","span":{"begin":202,"end":210},"obj":"Chemical"}],"attributes":[{"id":"A17932","pred":"chebi_id","subj":"T19189","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A64887","pred":"chebi_id","subj":"T97969","obj":"http://purl.obolibrary.org/obo/CHEBI_29031"},{"id":"A13409","pred":"chebi_id","subj":"T97969","obj":"http://purl.obolibrary.org/obo/CHEBI_53393"},{"id":"A77746","pred":"chebi_id","subj":"T97969","obj":"http://purl.obolibrary.org/obo/CHEBI_61431"},{"id":"A45199","pred":"chebi_id","subj":"T97969","obj":"http://purl.obolibrary.org/obo/CHEBI_64342"},{"id":"A53409","pred":"chebi_id","subj":"T44514","obj":"http://purl.obolibrary.org/obo/CHEBI_18243"},{"id":"A79167","pred":"chebi_id","subj":"T44514","obj":"http://purl.obolibrary.org/obo/CHEBI_59905"}],"text":" effects based on “on-off” and “steady-state” drug administration schedules have been reported for the stress-responsive hypothalamic-pituitary-adrenal (HPA) axis, the endogenous opioid system, and the dopamine system (Kreek 1973; Kreek et al. 2002; George et al. 2012). Acute o"}

{"project":"LitCovid-PubTator","denotations":[{"id":"3398","span":{"begin":202,"end":210},"obj":"Chemical"},{"id":"3401","span":{"begin":121,"end":151},"obj":"Disease"},{"id":"3402","span":{"begin":153,"end":156},"obj":"Disease"}],"attributes":[{"id":"A3398","pred":"tao:has_database_id","subj":"3398","obj":"MESH:D004298"},{"id":"A3401","pred":"tao:has_database_id","subj":"3401","obj":"MESH:D007029"},{"id":"A3402","pred":"tao:has_database_id","subj":"3402","obj":"MESH:D010661"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":" effects based on “on-off” and “steady-state” drug administration schedules have been reported for the stress-responsive hypothalamic-pituitary-adrenal (HPA) axis, the endogenous opioid system, and the dopamine system (Kreek 1973; Kreek et al. 2002; George et al. 2012). Acute o"}

{"project":"LitCovid-sentences","denotations":[{"id":"T1239","span":{"begin":244,"end":263},"obj":"Sentence"},{"id":"T1240","span":{"begin":264,"end":270},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":" effects based on “on-off” and “steady-state” drug administration schedules have been reported for the stress-responsive hypothalamic-pituitary-adrenal (HPA) axis, the endogenous opioid system, and the dopamine system (Kreek 1973; Kreek et al. 2002; George et al. 2012). Acute o"}

{"project":"2_test","denotations":[{"id":"32876803-4739193-62958321","span":{"begin":225,"end":229},"obj":"4739193"},{"id":"32876803-12209151-62958322","span":{"begin":244,"end":248},"obj":"12209151"},{"id":"32876803-22108506-62958323","span":{"begin":264,"end":268},"obj":"22108506"}],"text":" effects based on “on-off” and “steady-state” drug administration schedules have been reported for the stress-responsive hypothalamic-pituitary-adrenal (HPA) axis, the endogenous opioid system, and the dopamine system (Kreek 1973; Kreek et al. 2002; George et al. 2012). Acute o"}