PMC:7463108 / 85099-85434 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T821","span":{"begin":10,"end":17},"obj":"Body_part"},{"id":"T822","span":{"begin":46,"end":53},"obj":"Body_part"}],"attributes":[{"id":"A821","pred":"fma_id","subj":"T821","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A822","pred":"fma_id","subj":"T822","obj":"http://purl.org/sig/ont/fma/fma67257"}],"text":"The green protein represents MOR and the blue protein represents CCR5, while the bivalent ligand is colored in yellow. (b) Different binding pocket (green) for the triazole moiety of the bivalent ligand yellow) at 0 ns and 6.0 ns. (c) Construction of a chemical probe that interacts with both the MOR and CCR5 receptors simultaneously."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T883","span":{"begin":120,"end":121},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T884","span":{"begin":251,"end":252},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"The green protein represents MOR and the blue protein represents CCR5, while the bivalent ligand is colored in yellow. (b) Different binding pocket (green) for the triazole moiety of the bivalent ligand yellow) at 0 ns and 6.0 ns. (c) Construction of a chemical probe that interacts with both the MOR and CCR5 receptors simultaneously."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T60468","span":{"begin":10,"end":17},"obj":"Chemical"},{"id":"T47897","span":{"begin":46,"end":53},"obj":"Chemical"},{"id":"T43994","span":{"begin":90,"end":96},"obj":"Chemical"},{"id":"T54004","span":{"begin":164,"end":172},"obj":"Chemical"},{"id":"T59698","span":{"begin":196,"end":202},"obj":"Chemical"},{"id":"T303","span":{"begin":262,"end":267},"obj":"Chemical"}],"attributes":[{"id":"A1969","pred":"chebi_id","subj":"T60468","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A20073","pred":"chebi_id","subj":"T47897","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A84649","pred":"chebi_id","subj":"T43994","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A26426","pred":"chebi_id","subj":"T54004","obj":"http://purl.obolibrary.org/obo/CHEBI_38597"},{"id":"A86322","pred":"chebi_id","subj":"T59698","obj":"http://purl.obolibrary.org/obo/CHEBI_52214"},{"id":"A49535","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_50406"}],"text":"The green protein represents MOR and the blue protein represents CCR5, while the bivalent ligand is colored in yellow. (b) Different binding pocket (green) for the triazole moiety of the bivalent ligand yellow) at 0 ns and 6.0 ns. (c) Construction of a chemical probe that interacts with both the MOR and CCR5 receptors simultaneously."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2885","span":{"begin":29,"end":32},"obj":"Gene"},{"id":"2886","span":{"begin":65,"end":69},"obj":"Gene"},{"id":"2887","span":{"begin":297,"end":300},"obj":"Gene"},{"id":"2888","span":{"begin":305,"end":309},"obj":"Gene"},{"id":"2901","span":{"begin":164,"end":172},"obj":"Chemical"}],"attributes":[{"id":"A2885","pred":"tao:has_database_id","subj":"2885","obj":"Gene:4988"},{"id":"A2886","pred":"tao:has_database_id","subj":"2886","obj":"Gene:1234"},{"id":"A2887","pred":"tao:has_database_id","subj":"2887","obj":"Gene:4988"},{"id":"A2888","pred":"tao:has_database_id","subj":"2888","obj":"Gene:1234"},{"id":"A2901","pred":"tao:has_database_id","subj":"2901","obj":"MESH:D014230"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"The green protein represents MOR and the blue protein represents CCR5, while the bivalent ligand is colored in yellow. (b) Different binding pocket (green) for the triazole moiety of the bivalent ligand yellow) at 0 ns and 6.0 ns. (c) Construction of a chemical probe that interacts with both the MOR and CCR5 receptors simultaneously."}

{"project":"LitCovid-sentences","denotations":[{"id":"T1140","span":{"begin":0,"end":335},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"The green protein represents MOR and the blue protein represents CCR5, while the bivalent ligand is colored in yellow. (b) Different binding pocket (green) for the triazole moiety of the bivalent ligand yellow) at 0 ns and 6.0 ns. (c) Construction of a chemical probe that interacts with both the MOR and CCR5 receptors simultaneously."}