PMC:7463108 / 79628-80606
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T767 | 193-196 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T768 | 321-342 | Body_part | denotes | endoplasmic reticulum | http://purl.org/sig/ont/fma/fma63842 |
T769 | 400-409 | Body_part | denotes | G Protein | http://purl.org/sig/ont/fma/fma61788 |
T770 | 402-409 | Body_part | denotes | Protein | http://purl.org/sig/ont/fma/fma67257 |
T771 | 479-494 | Body_part | denotes | plasma membrane | http://purl.org/sig/ont/fma/fma63841 |
T772 | 657-660 | Body_part | denotes | CNS | http://purl.org/sig/ont/fma/fma55675 |
T773 | 661-665 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T774 | 694-697 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T168 | 657-660 | Body_part | denotes | CNS | http://purl.obolibrary.org/obo/UBERON_0001017 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T183 | 199-208 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T184 | 922-926 | Disease | denotes | HIVE | http://purl.obolibrary.org/obo/MONDO_0020689 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T824 | 65-71 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | humans |
T825 | 400-430 | http://purl.obolibrary.org/obo/PR_000030035 | denotes | G Protein-coupled receptors or |
T826 | 479-485 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
T827 | 486-494 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T828 | 581-586 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T829 | 657-660 | http://www.ebi.ac.uk/efo/EFO_0000302 | denotes | CNS |
T830 | 657-660 | http://www.ebi.ac.uk/efo/EFO_0000908 | denotes | CNS |
T831 | 657-660 | http://purl.obolibrary.org/obo/UBERON_0001017 | denotes | CNS |
T832 | 661-671 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
T833 | 849-854 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T834 | 889-892 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T37316 | 112-114 | Chemical | denotes | Lu | http://purl.obolibrary.org/obo/CHEBI_33382 |
T86315 | 402-409 | Chemical | denotes | Protein | http://purl.obolibrary.org/obo/CHEBI_16541 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
2708 | 19-24 | Gene | denotes | OPRM1 | Gene:4988 |
2709 | 129-134 | Gene | denotes | OPRM1 | Gene:4988 |
2710 | 587-590 | Gene | denotes | MOR | Gene:4988 |
2711 | 755-760 | Gene | denotes | MOR-1 | Gene:18390 |
2712 | 65-71 | Species | denotes | humans | Tax:9606 |
2713 | 581-586 | Species | denotes | human | Tax:9606 |
2714 | 849-854 | Species | denotes | human | Tax:9606 |
2715 | 694-697 | Species | denotes | HIV | Tax:12721 |
2716 | 193-208 | Disease | denotes | HIV-1 infection | MESH:D015658 |
2717 | 931-951 | Disease | denotes | cognitive impairment | MESH:D003072 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T158 | 147-155 | http://purl.obolibrary.org/obo/GO_0045292 | denotes | splicing |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1083 | 0-104 | Sentence | denotes | Nineteen different OPRM1 spliced variants have been described in humans (Pasternak 2004, 2014; Xu et al. |
T1084 | 105-121 | Sentence | denotes | 2014a; Lu et al. |
T1085 | 122-128 | Sentence | denotes | 2015). |
T1086 | 129-222 | Sentence | denotes | OPRM1 alternative splicing may also influence susceptibility to HIV-1 infection (Dever et al. |
T1087 | 223-235 | Sentence | denotes | 2012, 2014). |
T1088 | 236-512 | Sentence | denotes | Although many variants are thought to be non-functional and fail to traffic from the endoplasmic reticulum, increasing evidence suggests they may oligomerize other G Protein-coupled receptors or bind chaperones to assist in trafficking to the plasma membrane (Samoshkin et al. |
T1089 | 513-529 | Sentence | denotes | 2015; Zhu et al. |
T1090 | 530-536 | Sentence | denotes | 2019). |
T1091 | 537-711 | Sentence | denotes | Quantitative and qualitative differences in human MOR splice variant expression levels have been noted across different CNS cell types following exposure to HIV (Dever et al. |
T1092 | 712-724 | Sentence | denotes | 2012, 2014). |
T1093 | 725-811 | Sentence | denotes | Interestingly, an excitatory, MOR-1 K splice variant, that couples to GαS (Gris et al. |
T1094 | 812-878 | Sentence | denotes | 2010) is preferentially expressed in human astroglia (Dever et al. |
T1095 | 879-965 | Sentence | denotes | 2012) and has been shown to correlate with HIVE and cognitive impairment (Dever et al. |
T1096 | 966-978 | Sentence | denotes | 2012, 2014). |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T60 | 931-951 | Phenotype | denotes | cognitive impairment | http://purl.obolibrary.org/obo/HP_0100543 |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32876803-15464147-62958269 | 83-87 | 15464147 | denotes | 2004 |
32876803-26011641-62958271 | 122-126 | 26011641 | denotes | 2015 |
32876803-20525224-62958272 | 812-816 | 20525224 | denotes | 2010 |