PMC:7463108 / 76001-76559 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T734","span":{"begin":8,"end":11},"obj":"Body_part"},{"id":"T735","span":{"begin":46,"end":49},"obj":"Body_part"},{"id":"T736","span":{"begin":375,"end":378},"obj":"Body_part"},{"id":"T737","span":{"begin":422,"end":426},"obj":"Body_part"},{"id":"T738","span":{"begin":487,"end":490},"obj":"Body_part"}],"attributes":[{"id":"A734","pred":"fma_id","subj":"T734","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A735","pred":"fma_id","subj":"T735","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A736","pred":"fma_id","subj":"T736","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A737","pred":"fma_id","subj":"T737","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A738","pred":"fma_id","subj":"T738","obj":"http://purl.org/sig/ont/fma/fma278683"}],"text":"Besides HIV genetic diversity, differences in HIV tropism add another level of complexity. Morphine interactions can differ significantly between X4 and R5-tropic gp120 variants depending on the outcome measure (El-Hage et al. 2011b; Podhaizer et al. 2012; Balinang et al. 2017; Kim et al. 2018). Increased infectivity in the presence of morphine was noted for the R5-tropic HIV-1SF162 strain in a human hepatoma Huh7.5.1 cell line model, whereas the infectivity rate with the X4-tropic HIV-1LAI/IIIB strain was unaffected by morphine (El-Hage et al. 2011b)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T174","span":{"begin":153,"end":155},"obj":"Disease"},{"id":"T175","span":{"begin":365,"end":367},"obj":"Disease"},{"id":"T176","span":{"begin":404,"end":412},"obj":"Disease"}],"attributes":[{"id":"A174","pred":"mondo_id","subj":"T174","obj":"http://purl.obolibrary.org/obo/MONDO_0016654"},{"id":"A175","pred":"mondo_id","subj":"T175","obj":"http://purl.obolibrary.org/obo/MONDO_0016654"},{"id":"A176","pred":"mondo_id","subj":"T176","obj":"http://purl.obolibrary.org/obo/MONDO_0007256"}],"text":"Besides HIV genetic diversity, differences in HIV tropism add another level of complexity. Morphine interactions can differ significantly between X4 and R5-tropic gp120 variants depending on the outcome measure (El-Hage et al. 2011b; Podhaizer et al. 2012; Balinang et al. 2017; Kim et al. 2018). Increased infectivity in the presence of morphine was noted for the R5-tropic HIV-1SF162 strain in a human hepatoma Huh7.5.1 cell line model, whereas the infectivity rate with the X4-tropic HIV-1LAI/IIIB strain was unaffected by morphine (El-Hage et al. 2011b)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T805","span":{"begin":290,"end":294},"obj":"http://purl.obolibrary.org/obo/CLO_0001185"},{"id":"T806","span":{"begin":396,"end":397},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T807","span":{"begin":398,"end":403},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T808","span":{"begin":422,"end":431},"obj":"http://purl.obolibrary.org/obo/CLO_0000031"}],"text":"Besides HIV genetic diversity, differences in HIV tropism add another level of complexity. Morphine interactions can differ significantly between X4 and R5-tropic gp120 variants depending on the outcome measure (El-Hage et al. 2011b; Podhaizer et al. 2012; Balinang et al. 2017; Kim et al. 2018). Increased infectivity in the presence of morphine was noted for the R5-tropic HIV-1SF162 strain in a human hepatoma Huh7.5.1 cell line model, whereas the infectivity rate with the X4-tropic HIV-1LAI/IIIB strain was unaffected by morphine (El-Hage et al. 2011b)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T77864","span":{"begin":91,"end":99},"obj":"Chemical"},{"id":"T86034","span":{"begin":338,"end":346},"obj":"Chemical"},{"id":"T48999","span":{"begin":526,"end":534},"obj":"Chemical"}],"attributes":[{"id":"A96776","pred":"chebi_id","subj":"T77864","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A10395","pred":"chebi_id","subj":"T86034","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A86010","pred":"chebi_id","subj":"T86034","obj":"http://purl.obolibrary.org/obo/CHEBI_58097"},{"id":"A98323","pred":"chebi_id","subj":"T48999","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A40073","pred":"chebi_id","subj":"T48999","obj":"http://purl.obolibrary.org/obo/CHEBI_58097"}],"text":"Besides HIV genetic diversity, differences in HIV tropism add another level of complexity. Morphine interactions can differ significantly between X4 and R5-tropic gp120 variants depending on the outcome measure (El-Hage et al. 2011b; Podhaizer et al. 2012; Balinang et al. 2017; Kim et al. 2018). Increased infectivity in the presence of morphine was noted for the R5-tropic HIV-1SF162 strain in a human hepatoma Huh7.5.1 cell line model, whereas the infectivity rate with the X4-tropic HIV-1LAI/IIIB strain was unaffected by morphine (El-Hage et al. 2011b)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2591","span":{"begin":163,"end":168},"obj":"Gene"},{"id":"2592","span":{"begin":539,"end":543},"obj":"Gene"},{"id":"2593","span":{"begin":215,"end":219},"obj":"Gene"},{"id":"2594","span":{"begin":375,"end":380},"obj":"Species"},{"id":"2595","span":{"begin":398,"end":403},"obj":"Species"},{"id":"2596","span":{"begin":487,"end":492},"obj":"Species"},{"id":"2597","span":{"begin":8,"end":11},"obj":"Species"},{"id":"2598","span":{"begin":91,"end":99},"obj":"Chemical"},{"id":"2599","span":{"begin":338,"end":346},"obj":"Chemical"},{"id":"2600","span":{"begin":526,"end":534},"obj":"Chemical"},{"id":"2601","span":{"begin":46,"end":57},"obj":"Disease"},{"id":"2602","span":{"begin":404,"end":412},"obj":"Disease"},{"id":"2603","span":{"begin":413,"end":421},"obj":"CellLine"}],"attributes":[{"id":"A2591","pred":"tao:has_database_id","subj":"2591","obj":"Gene:3700"},{"id":"A2592","pred":"tao:has_database_id","subj":"2592","obj":"Gene:55510"},{"id":"A2593","pred":"tao:has_database_id","subj":"2593","obj":"Gene:55510"},{"id":"A2594","pred":"tao:has_database_id","subj":"2594","obj":"Tax:11676"},{"id":"A2595","pred":"tao:has_database_id","subj":"2595","obj":"Tax:9606"},{"id":"A2596","pred":"tao:has_database_id","subj":"2596","obj":"Tax:11676"},{"id":"A2597","pred":"tao:has_database_id","subj":"2597","obj":"Tax:12721"},{"id":"A2598","pred":"tao:has_database_id","subj":"2598","obj":"MESH:D009020"},{"id":"A2599","pred":"tao:has_database_id","subj":"2599","obj":"MESH:D009020"},{"id":"A2600","pred":"tao:has_database_id","subj":"2600","obj":"MESH:D009020"},{"id":"A2601","pred":"tao:has_database_id","subj":"2601","obj":"MESH:D015658"},{"id":"A2602","pred":"tao:has_database_id","subj":"2602","obj":"MESH:D006528"},{"id":"A2603","pred":"tao:has_database_id","subj":"2603","obj":"CVCL:E049"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Besides HIV genetic diversity, differences in HIV tropism add another level of complexity. Morphine interactions can differ significantly between X4 and R5-tropic gp120 variants depending on the outcome measure (El-Hage et al. 2011b; Podhaizer et al. 2012; Balinang et al. 2017; Kim et al. 2018). Increased infectivity in the presence of morphine was noted for the R5-tropic HIV-1SF162 strain in a human hepatoma Huh7.5.1 cell line model, whereas the infectivity rate with the X4-tropic HIV-1LAI/IIIB strain was unaffected by morphine (El-Hage et al. 2011b)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T149","span":{"begin":50,"end":57},"obj":"http://purl.obolibrary.org/obo/GO_0009606"}],"text":"Besides HIV genetic diversity, differences in HIV tropism add another level of complexity. Morphine interactions can differ significantly between X4 and R5-tropic gp120 variants depending on the outcome measure (El-Hage et al. 2011b; Podhaizer et al. 2012; Balinang et al. 2017; Kim et al. 2018). Increased infectivity in the presence of morphine was noted for the R5-tropic HIV-1SF162 strain in a human hepatoma Huh7.5.1 cell line model, whereas the infectivity rate with the X4-tropic HIV-1LAI/IIIB strain was unaffected by morphine (El-Hage et al. 2011b)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T1038","span":{"begin":0,"end":90},"obj":"Sentence"},{"id":"T1039","span":{"begin":91,"end":226},"obj":"Sentence"},{"id":"T1040","span":{"begin":227,"end":250},"obj":"Sentence"},{"id":"T1041","span":{"begin":251,"end":272},"obj":"Sentence"},{"id":"T1042","span":{"begin":273,"end":289},"obj":"Sentence"},{"id":"T1043","span":{"begin":290,"end":296},"obj":"Sentence"},{"id":"T1044","span":{"begin":297,"end":550},"obj":"Sentence"},{"id":"T1045","span":{"begin":551,"end":558},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Besides HIV genetic diversity, differences in HIV tropism add another level of complexity. Morphine interactions can differ significantly between X4 and R5-tropic gp120 variants depending on the outcome measure (El-Hage et al. 2011b; Podhaizer et al. 2012; Balinang et al. 2017; Kim et al. 2018). Increased infectivity in the presence of morphine was noted for the R5-tropic HIV-1SF162 strain in a human hepatoma Huh7.5.1 cell line model, whereas the infectivity rate with the X4-tropic HIV-1LAI/IIIB strain was unaffected by morphine (El-Hage et al. 2011b)."}

{"project":"2_test","denotations":[{"id":"32876803-22101471-62958244","span":{"begin":251,"end":255},"obj":"22101471"},{"id":"32876803-28099189-62958245","span":{"begin":273,"end":277},"obj":"28099189"}],"text":"Besides HIV genetic diversity, differences in HIV tropism add another level of complexity. Morphine interactions can differ significantly between X4 and R5-tropic gp120 variants depending on the outcome measure (El-Hage et al. 2011b; Podhaizer et al. 2012; Balinang et al. 2017; Kim et al. 2018). Increased infectivity in the presence of morphine was noted for the R5-tropic HIV-1SF162 strain in a human hepatoma Huh7.5.1 cell line model, whereas the infectivity rate with the X4-tropic HIV-1LAI/IIIB strain was unaffected by morphine (El-Hage et al. 2011b)."}