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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T555 11-14 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T556 73-78 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T557 214-219 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T558 989-1000 Body_part denotes vasculature http://purl.org/sig/ont/fma/fma69050
T559 1010-1028 Body_part denotes perivascular space http://purl.org/sig/ont/fma/fma323243|http://purl.org/sig/ont/fma/fma323272
T561 1036-1046 Body_part denotes parenchyma http://purl.org/sig/ont/fma/fma45732
T562 1054-1062 Body_part denotes striatum http://purl.org/sig/ont/fma/fma77618
T563 1141-1147 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T564 1208-1212 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T565 1345-1363 Body_part denotes perivascular space http://purl.org/sig/ont/fma/fma323243|http://purl.org/sig/ont/fma/fma323272
T567 1364-1374 Body_part denotes parenchyma http://purl.org/sig/ont/fma/fma45732
T568 1438-1447 Body_part denotes left-hand http://purl.org/sig/ont/fma/fma9714
T569 1540-1551 Body_part denotes capillaries http://purl.org/sig/ont/fma/fma63194
T570 1552-1574 Body_part denotes post-capillary venules http://purl.org/sig/ont/fma/fma63191
T571 1557-1566 Body_part denotes capillary http://purl.org/sig/ont/fma/fma63194
T572 1676-1688 Body_part denotes blood vessel http://purl.org/sig/ont/fma/fma63183
T573 1769-1781 Body_part denotes white matter http://purl.org/sig/ont/fma/fma83929
T574 1800-1808 Body_part denotes striatum http://purl.org/sig/ont/fma/fma77618
T575 1935-1941 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T576 1945-1951 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T577 1962-1970 Body_part denotes striatum http://purl.org/sig/ont/fma/fma77618
T578 2123-2131 Body_part denotes striatum http://purl.org/sig/ont/fma/fma77618
T579 2216-2222 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637
T580 2226-2232 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T110 73-78 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T111 214-219 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955
T112 989-1000 Body_part denotes vasculature http://purl.obolibrary.org/obo/UBERON_0002049
T113 1010-1028 Body_part denotes perivascular space http://purl.obolibrary.org/obo/UBERON_0014930
T114 1036-1046 Body_part denotes parenchyma http://purl.obolibrary.org/obo/UBERON_0000353
T115 1054-1062 Body_part denotes striatum http://purl.obolibrary.org/obo/UBERON_0002435
T116 1141-1147 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T117 1345-1363 Body_part denotes perivascular space http://purl.obolibrary.org/obo/UBERON_0014930
T118 1364-1374 Body_part denotes parenchyma http://purl.obolibrary.org/obo/UBERON_0000353
T119 1443-1447 Body_part denotes hand http://purl.obolibrary.org/obo/UBERON_0002398
T120 1552-1574 Body_part denotes post-capillary venules http://purl.obolibrary.org/obo/UBERON_0035428
T121 1557-1566 Body_part denotes capillary http://purl.obolibrary.org/obo/UBERON_0001982
T122 1676-1688 Body_part denotes blood vessel http://purl.obolibrary.org/obo/UBERON_0001981
T123 1676-1681 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T124 1682-1688 Body_part denotes vessel http://purl.obolibrary.org/obo/UBERON_0000055
T125 1769-1781 Body_part denotes white matter http://purl.obolibrary.org/obo/UBERON_0002316
T126 1800-1808 Body_part denotes striatum http://purl.obolibrary.org/obo/UBERON_0002435
T127 1901-1906 Body_part denotes Scale http://purl.obolibrary.org/obo/UBERON_0002542
T128 1935-1941 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T129 1962-1970 Body_part denotes striatum http://purl.obolibrary.org/obo/UBERON_0002435
T130 2123-2131 Body_part denotes striatum http://purl.obolibrary.org/obo/UBERON_0002435
T131 2216-2222 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T646 73-78 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T647 73-78 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T648 137-138 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T649 214-219 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T650 214-219 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T651 296-301 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T652 302-308 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brains
T653 302-308 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brains
T654 382-383 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T655 396-397 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T656 728-729 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T657 1208-1212 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T658 1657-1658 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T659 1676-1688 http://purl.obolibrary.org/obo/UBERON_0001981 denotes blood vessel
T660 1676-1688 http://www.ebi.ac.uk/efo/EFO_0000817 denotes blood vessel
T661 1945-1951 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T662 2226-2232 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T663 2351-2352 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T125 25-33 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T127 190-196 Chemical denotes tracer http://purl.obolibrary.org/obo/CHEBI_35204
T88715 326-334 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T13546 425-433 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T66413 561-569 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T134 659-667 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T136 717-725 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T138 855-863 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T81225 880-888 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T142 909-917 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T37279 1177-1190 Chemical denotes Hoechst 33342 http://purl.obolibrary.org/obo/CHEBI_51232
T79767 1213-1219 Chemical denotes nuclei http://purl.obolibrary.org/obo/CHEBI_33252
T42686 1274-1277 Chemical denotes DIC http://purl.obolibrary.org/obo/CHEBI_4305|http://purl.obolibrary.org/obo/CHEBI_53092
T5674 1403-1411 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T61069 1855-1860 Chemical denotes group http://purl.obolibrary.org/obo/CHEBI_24433
T21571 2008-2016 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T2284 2053-2065 Chemical denotes dolutegravir http://purl.obolibrary.org/obo/CHEBI_76010
T19714 2074-2082 Chemical denotes abacavir http://purl.obolibrary.org/obo/CHEBI_421707
T29469 2096-2106 Chemical denotes lamivudine http://purl.obolibrary.org/obo/CHEBI_63577
T20462 2186-2194 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T49655 2310-2318 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T84615 2335-2343 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
2041 112-115 Gene denotes Tat Gene:234724
2042 223-226 Gene denotes Tat Gene:234724
2043 252-255 Gene denotes Tat Gene:234724
2044 350-353 Gene denotes Tat Gene:234724
2045 618-621 Gene denotes Tat Gene:234724
2046 628-631 Gene denotes Tat Gene:234724
2047 810-813 Gene denotes Tat Gene:234724
2048 830-833 Gene denotes Tat Gene:234724
2049 850-853 Gene denotes Tat Gene:234724
2050 875-878 Gene denotes Tat Gene:234724
2051 1994-1997 Gene denotes Tat Gene:234724
2052 2265-2268 Gene denotes Tat Gene:234724
2053 2285-2288 Gene denotes Tat Gene:234724
2054 2305-2308 Gene denotes Tat Gene:234724
2055 2330-2333 Gene denotes Tat Gene:234724
2056 17-20 Gene denotes Tat Gene:6898
2057 290-293 Gene denotes Tat Gene:234724
2058 11-16 Species denotes HIV-1 Tax:11676
2059 266-270 Species denotes mice Tax:10090
2060 296-301 Species denotes mouse Tax:10090
2061 364-368 Species denotes mice Tax:10090
2062 889-893 Species denotes mice Tax:10090
2063 937-948 Species denotes horseradish Tax:3704
2064 1420-1424 Species denotes mice Tax:10090
2065 1846-1850 Species denotes mice Tax:10090
2066 2344-2348 Species denotes mice Tax:10090
2067 25-33 Chemical denotes morphine MESH:D009020
2068 326-334 Chemical denotes morphine MESH:D009020
2069 425-433 Chemical denotes morphine MESH:D009020
2070 561-569 Chemical denotes morphine MESH:D009020
2071 659-667 Chemical denotes morphine MESH:D009020
2072 717-725 Chemical denotes morphine MESH:D009020
2073 855-863 Chemical denotes morphine MESH:D009020
2074 880-888 Chemical denotes morphine MESH:D009020
2075 909-917 Chemical denotes morphine MESH:D009020
2076 1177-1190 Chemical denotes Hoechst 33342 MESH:C017807
2077 1403-1411 Chemical denotes morphine MESH:D009020
2078 2008-2016 Chemical denotes morphine MESH:D009020
2079 2053-2065 Chemical denotes dolutegravir MESH:C562325
2080 2074-2082 Chemical denotes abacavir MESH:C106538
2081 2096-2106 Chemical denotes lamivudine MESH:D019259
2082 2186-2194 Chemical denotes morphine MESH:D009020
2083 2310-2318 Chemical denotes morphine MESH:D009020
2084 2335-2343 Chemical denotes morphine MESH:D009020
2085 41-50 Disease denotes leakiness MESH:C535298

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T106 937-965 http://purl.obolibrary.org/obo/GO_0004601 denotes horseradish peroxidase (HRP)

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T792 95-385 Sentence denotes After 14 days of Tat induction, there was a significant increase in the 10 kDa (Cascade Blue®) tracer leakage into the brain in Tat + placebo as compared to Tat − placebo mice (*p < 0.05) and in Tat − mouse brains upon exposure to morphine as compared to Tat − placebo mice (*p < 0.05) (a).
T793 386-734 Sentence denotes There was a significant main effect of morphine, resulting in reduced integrity of the BBB and increased leakage of the higher molecular weight (40 kDa and 70 kDa) tracers in morphine-exposed groups as compared to the those groups (Tat + and Tat − together) not exposed to morphine (placebo) (#p < 0.05; significant main effect of morphine) (b, c).
T794 735-894 Sentence denotes Data represent the fold change in mean fluorescence intensity ± SEM; n = 8 Tat−/placebo, n = 6 Tat+/placebo, n = 9 Tat−/morphine, and n = 7 Tat+/morphine mice.
T795 895-1070 Sentence denotes Additionally, morphine exposure increased horseradish peroxidase (HRP) extravasation from the vasculature into the perivascular space and/or parenchyma in the striatum (d, e).
T796 1071-1308 Sentence denotes HRP antigenicity was detected by indirect immunofluorescence (red) in tissue sections counterstained with Hoechst 33342 (blue) to reveal cell nuclei and visualized by differential interference contrast (DIC)-enhanced confocal microscopy.
T797 1309-1470 Sentence denotes HRP extravasation into the striatal perivascular space/parenchyma was especially prevalent in morphine-exposed mice (arrowheads; left-hand panels in e versus d).
T798 1471-1741 Sentence denotes The dotted lines (············) indicate the approximate edge of the capillaries/post-capillary venules; while intermittent dotted lines (· · · · · · ·) indicate the approximate edge of a partly sectioned blood vessel that appears partially outside the plane of section.
T799 1742-1809 Sentence denotes The asterisks (*) indicate white matter tracts within the striatum.
T800 1810-1861 Sentence denotes Representative samples from ≥ n = 4 mice per group.
T801 1862-1900 Sentence denotes All images are the same magnification.
T802 1901-1919 Sentence denotes Scale bar = 10 μm.
T803 1920-1977 Sentence denotes Antiretroviral tissue-to-plasma ratios in striatum (f–g).
T804 1978-2196 Sentence denotes Irrespective of Tat exposure, morphine significantly reduced the levels of dolutegravir (f) and abacavir (g), but not lamivudine (h), within the striatum, as compared to placebo. (* p < 0.05; main effect for morphine).
T805 2197-2422 Sentence denotes Data represent the tissue-to-plasma ratios ± SEM sampled from n = 9 Tat−/placebo, n = 9 Tat+/placebo, n = 6 Tat−/morphine, and n = 8 Tat+/morphine mice. (a–h) Modified and reprinted with permission from Leibrand et al. (2019)

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T46 1010-1028 Phenotype denotes perivascular space http://purl.obolibrary.org/obo/HP_0012520
T47 1345-1363 Phenotype denotes perivascular space http://purl.obolibrary.org/obo/HP_0012520