PMC:7463108 / 51631-52076 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T508","span":{"begin":72,"end":81},"obj":"Body_part"},{"id":"T509","span":{"begin":169,"end":182},"obj":"Body_part"}],"attributes":[{"id":"A508","pred":"fma_id","subj":"T508","obj":"http://purl.org/sig/ont/fma/fma67314"},{"id":"A509","pred":"fma_id","subj":"T509","obj":"http://purl.org/sig/ont/fma/fma82760"}],"text":"Combined Tat and morphine promotes structural and functional defects in dendrites via α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPAR), N-methyl-D-aspartic acid receptors (NMDAR), and MOR, causing influxes of Na+ and/or Ca2+, compensatory increases in Na+/K+-dependent ATPase activity, and a rapid loss in ATP mobilization with an inability to extrude excess Na+ via Na+/K+-ATPase caused by mitochondrial hyperpolarization."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T598","span":{"begin":298,"end":306},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T599","span":{"begin":312,"end":313},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"text":"Combined Tat and morphine promotes structural and functional defects in dendrites via α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPAR), N-methyl-D-aspartic acid receptors (NMDAR), and MOR, causing influxes of Na+ and/or Ca2+, compensatory increases in Na+/K+-dependent ATPase activity, and a rapid loss in ATP mobilization with an inability to extrude excess Na+ via Na+/K+-ATPase caused by mitochondrial hyperpolarization."}

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{"project":"LitCovid-PubTator","denotations":[{"id":"1842","span":{"begin":206,"end":209},"obj":"Gene"},{"id":"1846","span":{"begin":9,"end":12},"obj":"Gene"}],"attributes":[{"id":"A1842","pred":"tao:has_database_id","subj":"1842","obj":"Gene:4988"},{"id":"A1846","pred":"tao:has_database_id","subj":"1846","obj":"Gene:6898"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Combined Tat and morphine promotes structural and functional defects in dendrites via α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPAR), N-methyl-D-aspartic acid receptors (NMDAR), and MOR, causing influxes of Na+ and/or Ca2+, compensatory increases in Na+/K+-dependent ATPase activity, and a rapid loss in ATP mobilization with an inability to extrude excess Na+ via Na+/K+-ATPase caused by mitochondrial hyperpolarization."}

{"project":"LitCovid-sentences","denotations":[{"id":"T734","span":{"begin":0,"end":445},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Combined Tat and morphine promotes structural and functional defects in dendrites via α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPAR), N-methyl-D-aspartic acid receptors (NMDAR), and MOR, causing influxes of Na+ and/or Ca2+, compensatory increases in Na+/K+-dependent ATPase activity, and a rapid loss in ATP mobilization with an inability to extrude excess Na+ via Na+/K+-ATPase caused by mitochondrial hyperpolarization."}