PMC:7463108 / 49701-50146 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T499","span":{"begin":11,"end":15},"obj":"Body_part"},{"id":"T500","span":{"begin":155,"end":164},"obj":"Body_part"}],"attributes":[{"id":"A499","pred":"fma_id","subj":"T499","obj":"http://purl.org/sig/ont/fma/fma54541"},{"id":"A500","pred":"fma_id","subj":"T500","obj":"http://purl.org/sig/ont/fma/fma67314"}],"text":"butions of glia cannot be excluded in this study (Fitting et al. 2014a). Combined morphine and Tat exposure accelerates the formation of Tat-induced focal dendritic varicosities/swelling via a MOR-related mechanism that was caused by focal increases in Na+ influx and [Ca2+]i, an overload of Na+/K+-ATPase, ATP depletion, and a collapse in mitochondrial inner membrane potential (Fitting et al. 2014a). Importantly, morphine’s additive effects w"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T591","span":{"begin":191,"end":192},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T592","span":{"begin":326,"end":327},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T593","span":{"begin":360,"end":368},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"}],"text":"butions of glia cannot be excluded in this study (Fitting et al. 2014a). Combined morphine and Tat exposure accelerates the formation of Tat-induced focal dendritic varicosities/swelling via a MOR-related mechanism that was caused by focal increases in Na+ influx and [Ca2+]i, an overload of Na+/K+-ATPase, ATP depletion, and a collapse in mitochondrial inner membrane potential (Fitting et al. 2014a). Importantly, morphine’s additive effects w"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T32116","span":{"begin":82,"end":90},"obj":"Chemical"},{"id":"T64562","span":{"begin":253,"end":255},"obj":"Chemical"},{"id":"T5757","span":{"begin":292,"end":294},"obj":"Chemical"},{"id":"T9480","span":{"begin":307,"end":310},"obj":"Chemical"}],"attributes":[{"id":"A96099","pred":"chebi_id","subj":"T32116","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A93790","pred":"chebi_id","subj":"T32116","obj":"http://purl.obolibrary.org/obo/CHEBI_58097"},{"id":"A88457","pred":"chebi_id","subj":"T64562","obj":"http://purl.obolibrary.org/obo/CHEBI_26708"},{"id":"A13351","pred":"chebi_id","subj":"T5757","obj":"http://purl.obolibrary.org/obo/CHEBI_26708"},{"id":"A21099","pred":"chebi_id","subj":"T9480","obj":"http://purl.obolibrary.org/obo/CHEBI_15422"},{"id":"A72149","pred":"chebi_id","subj":"T9480","obj":"http://purl.obolibrary.org/obo/CHEBI_30616"}],"text":"butions of glia cannot be excluded in this study (Fitting et al. 2014a). Combined morphine and Tat exposure accelerates the formation of Tat-induced focal dendritic varicosities/swelling via a MOR-related mechanism that was caused by focal increases in Na+ influx and [Ca2+]i, an overload of Na+/K+-ATPase, ATP depletion, and a collapse in mitochondrial inner membrane potential (Fitting et al. 2014a). Importantly, morphine’s additive effects w"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1910","span":{"begin":95,"end":98},"obj":"Gene"},{"id":"1911","span":{"begin":137,"end":140},"obj":"Gene"},{"id":"1912","span":{"begin":193,"end":196},"obj":"Gene"},{"id":"1925","span":{"begin":82,"end":90},"obj":"Chemical"},{"id":"1926","span":{"begin":269,"end":273},"obj":"Chemical"},{"id":"1927","span":{"begin":307,"end":310},"obj":"Chemical"},{"id":"1928","span":{"begin":416,"end":424},"obj":"Chemical"},{"id":"1937","span":{"begin":149,"end":186},"obj":"Disease"}],"attributes":[{"id":"A1910","pred":"tao:has_database_id","subj":"1910","obj":"Gene:6898"},{"id":"A1911","pred":"tao:has_database_id","subj":"1911","obj":"Gene:6898"},{"id":"A1912","pred":"tao:has_database_id","subj":"1912","obj":"Gene:4988"},{"id":"A1925","pred":"tao:has_database_id","subj":"1925","obj":"MESH:D009020"},{"id":"A1926","pred":"tao:has_database_id","subj":"1926","obj":"MESH:D000069285"},{"id":"A1927","pred":"tao:has_database_id","subj":"1927","obj":"MESH:D000255"},{"id":"A1928","pred":"tao:has_database_id","subj":"1928","obj":"MESH:D009020"},{"id":"A1937","pred":"tao:has_database_id","subj":"1937","obj":"MESH:D014647"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"butions of glia cannot be excluded in this study (Fitting et al. 2014a). Combined morphine and Tat exposure accelerates the formation of Tat-induced focal dendritic varicosities/swelling via a MOR-related mechanism that was caused by focal increases in Na+ influx and [Ca2+]i, an overload of Na+/K+-ATPase, ATP depletion, and a collapse in mitochondrial inner membrane potential (Fitting et al. 2014a). Importantly, morphine’s additive effects w"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T87","span":{"begin":124,"end":133},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"butions of glia cannot be excluded in this study (Fitting et al. 2014a). Combined morphine and Tat exposure accelerates the formation of Tat-induced focal dendritic varicosities/swelling via a MOR-related mechanism that was caused by focal increases in Na+ influx and [Ca2+]i, an overload of Na+/K+-ATPase, ATP depletion, and a collapse in mitochondrial inner membrane potential (Fitting et al. 2014a). Importantly, morphine’s additive effects w"}

{"project":"LitCovid-sentences","denotations":[{"id":"T719","span":{"begin":65,"end":72},"obj":"Sentence"},{"id":"T720","span":{"begin":73,"end":394},"obj":"Sentence"},{"id":"T721","span":{"begin":395,"end":402},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"butions of glia cannot be excluded in this study (Fitting et al. 2014a). Combined morphine and Tat exposure accelerates the formation of Tat-induced focal dendritic varicosities/swelling via a MOR-related mechanism that was caused by focal increases in Na+ influx and [Ca2+]i, an overload of Na+/K+-ATPase, ATP depletion, and a collapse in mitochondrial inner membrane potential (Fitting et al. 2014a). Importantly, morphine’s additive effects w"}