PMC:7463108 / 48637-48984
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T485 | 12-15 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
| T486 | 40-49 | Body_part | denotes | microglia | http://purl.org/sig/ont/fma/fma68923 |
| T487 | 90-98 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
| T488 | 139-147 | Body_part | denotes | cytokine | http://purl.org/sig/ont/fma/fma84050 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T132 | 235-238 | Disease | denotes | UPS | http://purl.obolibrary.org/obo/MONDO_0002142 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T582 | 40-49 | http://purl.obolibrary.org/obo/CL_0000129 | denotes | microglia |
| T583 | 55-56 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T584 | 279-280 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
| T585 | 322-323 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T495 | 66-69 | Chemical | denotes | ROS | http://purl.obolibrary.org/obo/CHEBI_26523 |
| T496 | 125-133 | Chemical | denotes | morphine | http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097 |
| T498 | 318-320 | Chemical | denotes | NF | http://purl.obolibrary.org/obo/CHEBI_141424|http://purl.obolibrary.org/obo/CHEBI_25573|http://purl.obolibrary.org/obo/CHEBI_1224 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1769 | 25-28 | Gene | denotes | MOR | Gene:4988 |
| 1770 | 318-323 | Gene | denotes | NF-κB | Gene:4790 |
| 1772 | 12-15 | Species | denotes | HIV | Tax:12721 |
| 1787 | 125-133 | Chemical | denotes | morphine | MESH:D009020 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T81 | 90-109 | http://purl.obolibrary.org/obo/GO_0001816 | denotes | cytokine production |
| T82 | 113-133 | http://purl.obolibrary.org/obo/GO_0043278 | denotes | response to morphine |
| T83 | 258-269 | http://purl.obolibrary.org/obo/GO_0009056 | denotes | degradation |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T712 | 0-347 | Sentence | denotes | Thus, while HIV-exposed, MOR-expressing microglia show a burst of ROS and proinflammatory cytokine production in response to morphine, the cytokine release collapses within 24 h seemingly because sustained opiate exposure inhibits the UPS thereby preventing degradation of the IκB subunit and nuclear translocation of NF-κB (Turchan-Cholewo et al. |