PMC:7463108 / 46374-46626 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T465","span":{"begin":19,"end":22},"obj":"Body_part"},{"id":"T466","span":{"begin":33,"end":36},"obj":"Body_part"},{"id":"T467","span":{"begin":141,"end":151},"obj":"Body_part"},{"id":"T468","span":{"begin":199,"end":208},"obj":"Body_part"},{"id":"T469","span":{"begin":209,"end":220},"obj":"Body_part"}],"attributes":[{"id":"A465","pred":"fma_id","subj":"T465","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A466","pred":"fma_id","subj":"T466","obj":"http://purl.org/sig/ont/fma/fma55675"},{"id":"A467","pred":"fma_id","subj":"T467","obj":"http://purl.org/sig/ont/fma/fma54537"},{"id":"A468","pred":"fma_id","subj":"T468","obj":"http://purl.org/sig/ont/fma/fma68923"},{"id":"A469","pred":"fma_id","subj":"T469","obj":"http://purl.org/sig/ont/fma/fma63261"}],"text":"Opioids exacerbate HIV-1-induced CNS inflammation, in part, by increasing CCL5 and augmenting CCR5-dependent increases in CCL2 production by astrocytes resulting in the activation and recruitment of microglia/macrophages and spiraling inflammation (k)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T97","span":{"begin":33,"end":36},"obj":"Body_part"}],"attributes":[{"id":"A97","pred":"uberon_id","subj":"T97","obj":"http://purl.obolibrary.org/obo/UBERON_0001017"}],"text":"Opioids exacerbate HIV-1-induced CNS inflammation, in part, by increasing CCL5 and augmenting CCR5-dependent increases in CCL2 production by astrocytes resulting in the activation and recruitment of microglia/macrophages and spiraling inflammation (k)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T124","span":{"begin":37,"end":49},"obj":"Disease"},{"id":"T125","span":{"begin":235,"end":247},"obj":"Disease"}],"attributes":[{"id":"A124","pred":"mondo_id","subj":"T124","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A125","pred":"mondo_id","subj":"T125","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"Opioids exacerbate HIV-1-induced CNS inflammation, in part, by increasing CCL5 and augmenting CCR5-dependent increases in CCL2 production by astrocytes resulting in the activation and recruitment of microglia/macrophages and spiraling inflammation (k)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T564","span":{"begin":33,"end":36},"obj":"http://www.ebi.ac.uk/efo/EFO_0000302"},{"id":"T565","span":{"begin":33,"end":36},"obj":"http://www.ebi.ac.uk/efo/EFO_0000908"},{"id":"T566","span":{"begin":33,"end":36},"obj":"http://purl.obolibrary.org/obo/UBERON_0001017"},{"id":"T567","span":{"begin":141,"end":151},"obj":"http://purl.obolibrary.org/obo/CL_0000127"},{"id":"T568","span":{"begin":169,"end":179},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T569","span":{"begin":199,"end":208},"obj":"http://purl.obolibrary.org/obo/CL_0000129"}],"text":"Opioids exacerbate HIV-1-induced CNS inflammation, in part, by increasing CCL5 and augmenting CCR5-dependent increases in CCL2 production by astrocytes resulting in the activation and recruitment of microglia/macrophages and spiraling inflammation (k)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1649","span":{"begin":74,"end":78},"obj":"Gene"},{"id":"1650","span":{"begin":94,"end":98},"obj":"Gene"},{"id":"1651","span":{"begin":122,"end":126},"obj":"Gene"},{"id":"1673","span":{"begin":19,"end":24},"obj":"Species"},{"id":"1677","span":{"begin":33,"end":49},"obj":"Disease"},{"id":"1678","span":{"begin":235,"end":247},"obj":"Disease"}],"attributes":[{"id":"A1649","pred":"tao:has_database_id","subj":"1649","obj":"Gene:6352"},{"id":"A1650","pred":"tao:has_database_id","subj":"1650","obj":"Gene:1234"},{"id":"A1651","pred":"tao:has_database_id","subj":"1651","obj":"Gene:6347"},{"id":"A1673","pred":"tao:has_database_id","subj":"1673","obj":"Tax:11676"},{"id":"A1677","pred":"tao:has_database_id","subj":"1677","obj":"MESH:D007249"},{"id":"A1678","pred":"tao:has_database_id","subj":"1678","obj":"MESH:D007249"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Opioids exacerbate HIV-1-induced CNS inflammation, in part, by increasing CCL5 and augmenting CCR5-dependent increases in CCL2 production by astrocytes resulting in the activation and recruitment of microglia/macrophages and spiraling inflammation (k)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T78","span":{"begin":37,"end":49},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T79","span":{"begin":122,"end":137},"obj":"http://purl.obolibrary.org/obo/GO_0071605"},{"id":"T80","span":{"begin":235,"end":247},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Opioids exacerbate HIV-1-induced CNS inflammation, in part, by increasing CCL5 and augmenting CCR5-dependent increases in CCL2 production by astrocytes resulting in the activation and recruitment of microglia/macrophages and spiraling inflammation (k)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T694","span":{"begin":0,"end":252},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Opioids exacerbate HIV-1-induced CNS inflammation, in part, by increasing CCL5 and augmenting CCR5-dependent increases in CCL2 production by astrocytes resulting in the activation and recruitment of microglia/macrophages and spiraling inflammation (k)."}