PMC:7463108 / 45636-46184
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7463108","sourcedb":"PMC","sourceid":"7463108","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7463108","text":"In wild-type mice, Tat ± morphine administration markedly increases the proportion of CCL2 immunoreactive astrocytes (g) or macrophages/microglia (h) [*p \u003c 0.05 vs. other groups in wild-type or CCL5(−/−) mice; bp \u003c 0.05 vs. vehicle- or Tat plus morphine-treated wild-type mice; #p \u003c 0.05 vs. equivalent treatment in wild-type mice], while in CCL5 null mice, significant increases in CCL2 immunoreactivity were only seen in macrophages/microglia co-exposed to Tat and morphine (§p \u003c 0.05 vs. vehicle injected CCL5 knockout mice) (see, El-Hage et al.","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T457","span":{"begin":106,"end":116},"obj":"Body_part"},{"id":"T458","span":{"begin":124,"end":135},"obj":"Body_part"},{"id":"T459","span":{"begin":136,"end":145},"obj":"Body_part"},{"id":"T460","span":{"begin":423,"end":434},"obj":"Body_part"},{"id":"T461","span":{"begin":435,"end":444},"obj":"Body_part"}],"attributes":[{"id":"A457","pred":"fma_id","subj":"T457","obj":"http://purl.org/sig/ont/fma/fma54537"},{"id":"A458","pred":"fma_id","subj":"T458","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A459","pred":"fma_id","subj":"T459","obj":"http://purl.org/sig/ont/fma/fma68923"},{"id":"A460","pred":"fma_id","subj":"T460","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A461","pred":"fma_id","subj":"T461","obj":"http://purl.org/sig/ont/fma/fma68923"},{"subj":"T457","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T458","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T459","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T460","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T461","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T557","span":{"begin":106,"end":116},"obj":"http://purl.obolibrary.org/obo/CL_0000127"},{"id":"T558","span":{"begin":136,"end":145},"obj":"http://purl.obolibrary.org/obo/CL_0000129"},{"id":"T559","span":{"begin":146,"end":153},"obj":"http://purl.obolibrary.org/obo/CLO_0003797"},{"id":"T560","span":{"begin":146,"end":153},"obj":"http://purl.obolibrary.org/obo/PR_000008725"},{"id":"T561","span":{"begin":146,"end":153},"obj":"http://purl.obolibrary.org/obo/UBERON_0000007"},{"id":"T562","span":{"begin":435,"end":444},"obj":"http://purl.obolibrary.org/obo/CL_0000129"}],"attributes":[{"subj":"T557","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T558","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T559","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T560","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T561","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T562","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T464","span":{"begin":25,"end":33},"obj":"Chemical"},{"id":"T466","span":{"begin":245,"end":253},"obj":"Chemical"},{"id":"T468","span":{"begin":467,"end":475},"obj":"Chemical"}],"attributes":[{"id":"A464","pred":"chebi_id","subj":"T464","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A465","pred":"chebi_id","subj":"T464","obj":"http://purl.obolibrary.org/obo/CHEBI_58097"},{"id":"A466","pred":"chebi_id","subj":"T466","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A467","pred":"chebi_id","subj":"T466","obj":"http://purl.obolibrary.org/obo/CHEBI_58097"},{"id":"A468","pred":"chebi_id","subj":"T468","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A469","pred":"chebi_id","subj":"T468","obj":"http://purl.obolibrary.org/obo/CHEBI_58097"},{"subj":"T464","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T466","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T468","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"1639","span":{"begin":19,"end":22},"obj":"Gene"},{"id":"1640","span":{"begin":86,"end":90},"obj":"Gene"},{"id":"1641","span":{"begin":194,"end":198},"obj":"Gene"},{"id":"1642","span":{"begin":236,"end":239},"obj":"Gene"},{"id":"1643","span":{"begin":342,"end":346},"obj":"Gene"},{"id":"1644","span":{"begin":383,"end":387},"obj":"Gene"},{"id":"1645","span":{"begin":459,"end":462},"obj":"Gene"},{"id":"1646","span":{"begin":508,"end":512},"obj":"Gene"},{"id":"1659","span":{"begin":537,"end":541},"obj":"Gene"},{"id":"1666","span":{"begin":13,"end":17},"obj":"Species"},{"id":"1667","span":{"begin":204,"end":208},"obj":"Species"},{"id":"1668","span":{"begin":272,"end":276},"obj":"Species"},{"id":"1669","span":{"begin":326,"end":330},"obj":"Species"},{"id":"1670","span":{"begin":352,"end":356},"obj":"Species"},{"id":"1671","span":{"begin":522,"end":526},"obj":"Species"}],"attributes":[{"id":"A1639","pred":"tao:has_database_id","subj":"1639","obj":"Gene:234724"},{"id":"A1640","pred":"tao:has_database_id","subj":"1640","obj":"Gene:20296"},{"id":"A1641","pred":"tao:has_database_id","subj":"1641","obj":"Gene:20304"},{"id":"A1642","pred":"tao:has_database_id","subj":"1642","obj":"Gene:234724"},{"id":"A1643","pred":"tao:has_database_id","subj":"1643","obj":"Gene:20304"},{"id":"A1644","pred":"tao:has_database_id","subj":"1644","obj":"Gene:20296"},{"id":"A1645","pred":"tao:has_database_id","subj":"1645","obj":"Gene:234724"},{"id":"A1646","pred":"tao:has_database_id","subj":"1646","obj":"Gene:20304"},{"id":"A1659","pred":"tao:has_database_id","subj":"1659","obj":"Gene:55510"},{"id":"A1666","pred":"tao:has_database_id","subj":"1666","obj":"Tax:10090"},{"id":"A1667","pred":"tao:has_database_id","subj":"1667","obj":"Tax:10090"},{"id":"A1668","pred":"tao:has_database_id","subj":"1668","obj":"Tax:10090"},{"id":"A1669","pred":"tao:has_database_id","subj":"1669","obj":"Tax:10090"},{"id":"A1670","pred":"tao:has_database_id","subj":"1670","obj":"Tax:10090"},{"id":"A1671","pred":"tao:has_database_id","subj":"1671","obj":"Tax:10090"},{"subj":"1639","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1640","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1641","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1642","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1643","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1644","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1645","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1646","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1659","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1666","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1667","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1668","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1669","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1670","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1671","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T690","span":{"begin":0,"end":548},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T690","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#ecd093","default":true},{"id":"LitCovid-PD-CLO","color":"#b693ec"},{"id":"LitCovid-PD-CHEBI","color":"#93ec9c"},{"id":"LitCovid-PubTator","color":"#ec93a3"},{"id":"LitCovid-sentences","color":"#93bdec"}]}]}}