PMC:7463108 / 38920-39174 JSONTXT

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    LitCovid-PD-FMA-UBERON

    {"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T385","span":{"begin":148,"end":151},"obj":"Body_part"},{"id":"T386","span":{"begin":218,"end":225},"obj":"Body_part"}],"attributes":[{"id":"A385","pred":"fma_id","subj":"T385","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A386","pred":"fma_id","subj":"T386","obj":"http://purl.org/sig/ont/fma/fma54527"}],"text":"GABA function • HIVBaL (R5)\n• gp120 (ADA, MN, and IIIB)\n• Tat1–86 No Morphine • Tat or morphine ↓ KCC2 levels via CCR5\n• ↑ KCC2 prevents Tat and R5 HIV, gp120, but not X4, gp120 neurotoxicity ± morphine Human, primary neurons, hNPCs (Barbour et al. 2020)"}

    LitCovid-PD-MONDO

    {"project":"LitCovid-PD-MONDO","denotations":[{"id":"T111","span":{"begin":24,"end":26},"obj":"Disease"},{"id":"T112","span":{"begin":37,"end":40},"obj":"Disease"},{"id":"T113","span":{"begin":145,"end":147},"obj":"Disease"},{"id":"T114","span":{"begin":178,"end":191},"obj":"Disease"}],"attributes":[{"id":"A111","pred":"mondo_id","subj":"T111","obj":"http://purl.obolibrary.org/obo/MONDO_0016654"},{"id":"A112","pred":"mondo_id","subj":"T112","obj":"http://purl.obolibrary.org/obo/MONDO_0007064"},{"id":"A113","pred":"mondo_id","subj":"T113","obj":"http://purl.obolibrary.org/obo/MONDO_0016654"},{"id":"A114","pred":"mondo_id","subj":"T114","obj":"http://purl.obolibrary.org/obo/MONDO_0005527"}],"text":"GABA function • HIVBaL (R5)\n• gp120 (ADA, MN, and IIIB)\n• Tat1–86 No Morphine • Tat or morphine ↓ KCC2 levels via CCR5\n• ↑ KCC2 prevents Tat and R5 HIV, gp120, but not X4, gp120 neurotoxicity ± morphine Human, primary neurons, hNPCs (Barbour et al. 2020)"}

    LitCovid-PD-CLO

    {"project":"LitCovid-PD-CLO","denotations":[{"id":"T486","span":{"begin":203,"end":208},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"}],"text":"GABA function • HIVBaL (R5)\n• gp120 (ADA, MN, and IIIB)\n• Tat1–86 No Morphine • Tat or morphine ↓ KCC2 levels via CCR5\n• ↑ KCC2 prevents Tat and R5 HIV, gp120, but not X4, gp120 neurotoxicity ± morphine Human, primary neurons, hNPCs (Barbour et al. 2020)"}

    LitCovid-PD-CHEBI

    {"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T398","span":{"begin":0,"end":4},"obj":"Chemical"},{"id":"T399","span":{"begin":37,"end":40},"obj":"Chemical"},{"id":"T400","span":{"begin":42,"end":44},"obj":"Chemical"},{"id":"T401","span":{"begin":69,"end":77},"obj":"Chemical"},{"id":"T402","span":{"begin":87,"end":95},"obj":"Chemical"},{"id":"T404","span":{"begin":194,"end":202},"obj":"Chemical"}],"attributes":[{"id":"A398","pred":"chebi_id","subj":"T398","obj":"http://purl.obolibrary.org/obo/CHEBI_16865"},{"id":"A399","pred":"chebi_id","subj":"T399","obj":"http://purl.obolibrary.org/obo/CHEBI_39048"},{"id":"A400","pred":"chebi_id","subj":"T400","obj":"http://purl.obolibrary.org/obo/CHEBI_141442"},{"id":"A401","pred":"chebi_id","subj":"T401","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A402","pred":"chebi_id","subj":"T402","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A403","pred":"chebi_id","subj":"T402","obj":"http://purl.obolibrary.org/obo/CHEBI_58097"},{"id":"A404","pred":"chebi_id","subj":"T404","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A405","pred":"chebi_id","subj":"T404","obj":"http://purl.obolibrary.org/obo/CHEBI_58097"}],"text":"GABA function • HIVBaL (R5)\n• gp120 (ADA, MN, and IIIB)\n• Tat1–86 No Morphine • Tat or morphine ↓ KCC2 levels via CCR5\n• ↑ KCC2 prevents Tat and R5 HIV, gp120, but not X4, gp120 neurotoxicity ± morphine Human, primary neurons, hNPCs (Barbour et al. 2020)"}

    LitCovid-sentences

    {"project":"LitCovid-sentences","denotations":[{"id":"T604","span":{"begin":0,"end":27},"obj":"Sentence"},{"id":"T605","span":{"begin":28,"end":55},"obj":"Sentence"},{"id":"T606","span":{"begin":56,"end":118},"obj":"Sentence"},{"id":"T607","span":{"begin":119,"end":248},"obj":"Sentence"},{"id":"T608","span":{"begin":249,"end":254},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"GABA function • HIVBaL (R5)\n• gp120 (ADA, MN, and IIIB)\n• Tat1–86 No Morphine • Tat or morphine ↓ KCC2 levels via CCR5\n• ↑ KCC2 prevents Tat and R5 HIV, gp120, but not X4, gp120 neurotoxicity ± morphine Human, primary neurons, hNPCs (Barbour et al. 2020)"}