PMC:7463108 / 23298-23555 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T171","span":{"begin":130,"end":137},"obj":"Body_part"},{"id":"T172","span":{"begin":158,"end":162},"obj":"Body_part"},{"id":"T173","span":{"begin":220,"end":225},"obj":"Body_part"}],"attributes":[{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A172","pred":"fma_id","subj":"T172","obj":"http://purl.org/sig/ont/fma/fma67122"},{"id":"A173","pred":"fma_id","subj":"T173","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"SIVmacR71/17E\nTat No info • Morphine (escalating doses of 1–3 mg/kg i.m., q.i.d., 12 months)\n• Morphine in vitro • SIV ↑ Synaptic protein HSPA5\n• Tat ↑ HSPA5 mRNA (in vitro) Rhesus macaques;\nHuman,\nSH-SY5Y neuroblastoma cells in vitro (Pendyala et al. 2015)"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T62","span":{"begin":115,"end":118},"obj":"Disease"},{"id":"T63","span":{"begin":206,"end":219},"obj":"Disease"}],"attributes":[{"id":"A62","pred":"mondo_id","subj":"T62","obj":"http://purl.obolibrary.org/obo/MONDO_0010029"},{"id":"A63","pred":"mondo_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/MONDO_0005072"}],"text":"SIVmacR71/17E\nTat No info • Morphine (escalating doses of 1–3 mg/kg i.m., q.i.d., 12 months)\n• Morphine in vitro • SIV ↑ Synaptic protein HSPA5\n• Tat ↑ HSPA5 mRNA (in vitro) Rhesus macaques;\nHuman,\nSH-SY5Y neuroblastoma cells in vitro (Pendyala et al. 2015)"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T210","span":{"begin":174,"end":189},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9544"},{"id":"T211","span":{"begin":191,"end":196},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_9606"},{"id":"T212","span":{"begin":198,"end":205},"obj":"http://purl.obolibrary.org/obo/CLO_0009015"},{"id":"T213","span":{"begin":198,"end":205},"obj":"http://purl.obolibrary.org/obo/CLO_0051795"},{"id":"T214","span":{"begin":198,"end":205},"obj":"http://purl.obolibrary.org/obo/CLO_0052135"},{"id":"T215","span":{"begin":198,"end":205},"obj":"http://purl.obolibrary.org/obo/CLO_0052139"},{"id":"T216","span":{"begin":198,"end":205},"obj":"http://purl.obolibrary.org/obo/CLO_0052141"},{"id":"T217","span":{"begin":220,"end":234},"obj":"http://purl.obolibrary.org/obo/CL_0001034"}],"text":"SIVmacR71/17E\nTat No info • Morphine (escalating doses of 1–3 mg/kg i.m., q.i.d., 12 months)\n• Morphine in vitro • SIV ↑ Synaptic protein HSPA5\n• Tat ↑ HSPA5 mRNA (in vitro) Rhesus macaques;\nHuman,\nSH-SY5Y neuroblastoma cells in vitro (Pendyala et al. 2015)"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T153","span":{"begin":28,"end":36},"obj":"Chemical"},{"id":"T154","span":{"begin":95,"end":103},"obj":"Chemical"},{"id":"T155","span":{"begin":130,"end":137},"obj":"Chemical"},{"id":"T156","span":{"begin":198,"end":200},"obj":"Chemical"}],"attributes":[{"id":"A153","pred":"chebi_id","subj":"T153","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A154","pred":"chebi_id","subj":"T154","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A155","pred":"chebi_id","subj":"T155","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A156","pred":"chebi_id","subj":"T156","obj":"http://purl.obolibrary.org/obo/CHEBI_29312"},{"id":"A157","pred":"chebi_id","subj":"T156","obj":"http://purl.obolibrary.org/obo/CHEBI_73651"}],"text":"SIVmacR71/17E\nTat No info • Morphine (escalating doses of 1–3 mg/kg i.m., q.i.d., 12 months)\n• Morphine in vitro • SIV ↑ Synaptic protein HSPA5\n• Tat ↑ HSPA5 mRNA (in vitro) Rhesus macaques;\nHuman,\nSH-SY5Y neuroblastoma cells in vitro (Pendyala et al. 2015)"}

{"project":"LitCovid-PubTator","denotations":[{"id":"562","span":{"begin":138,"end":143},"obj":"Gene"},{"id":"563","span":{"begin":152,"end":157},"obj":"Gene"},{"id":"650","span":{"begin":174,"end":189},"obj":"Species"},{"id":"651","span":{"begin":191,"end":196},"obj":"Species"},{"id":"714","span":{"begin":115,"end":118},"obj":"Gene"},{"id":"737","span":{"begin":146,"end":149},"obj":"Gene"},{"id":"776","span":{"begin":206,"end":219},"obj":"Disease"},{"id":"777","span":{"begin":236,"end":244},"obj":"Disease"},{"id":"785","span":{"begin":198,"end":205},"obj":"CellLine"}],"attributes":[{"id":"A562","pred":"tao:has_database_id","subj":"562","obj":"Gene:14828"},{"id":"A563","pred":"tao:has_database_id","subj":"563","obj":"Gene:14828"},{"id":"A650","pred":"tao:has_database_id","subj":"650","obj":"Tax:9544"},{"id":"A651","pred":"tao:has_database_id","subj":"651","obj":"Tax:9606"},{"id":"A714","pred":"tao:has_database_id","subj":"714","obj":"Gene:8114"},{"id":"A737","pred":"tao:has_database_id","subj":"737","obj":"Gene:6898"},{"id":"A776","pred":"tao:has_database_id","subj":"776","obj":"MESH:D009447"},{"id":"A785","pred":"tao:has_database_id","subj":"785","obj":"CVCL:0019"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"SIVmacR71/17E\nTat No info • Morphine (escalating doses of 1–3 mg/kg i.m., q.i.d., 12 months)\n• Morphine in vitro • SIV ↑ Synaptic protein HSPA5\n• Tat ↑ HSPA5 mRNA (in vitro) Rhesus macaques;\nHuman,\nSH-SY5Y neuroblastoma cells in vitro (Pendyala et al. 2015)"}

{"project":"LitCovid-sentences","denotations":[{"id":"T348","span":{"begin":0,"end":13},"obj":"Sentence"},{"id":"T349","span":{"begin":14,"end":92},"obj":"Sentence"},{"id":"T350","span":{"begin":93,"end":143},"obj":"Sentence"},{"id":"T351","span":{"begin":144,"end":190},"obj":"Sentence"},{"id":"T352","span":{"begin":191,"end":197},"obj":"Sentence"},{"id":"T353","span":{"begin":198,"end":251},"obj":"Sentence"},{"id":"T354","span":{"begin":252,"end":257},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"SIVmacR71/17E\nTat No info • Morphine (escalating doses of 1–3 mg/kg i.m., q.i.d., 12 months)\n• Morphine in vitro • SIV ↑ Synaptic protein HSPA5\n• Tat ↑ HSPA5 mRNA (in vitro) Rhesus macaques;\nHuman,\nSH-SY5Y neuroblastoma cells in vitro (Pendyala et al. 2015)"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T31","span":{"begin":206,"end":219},"obj":"Phenotype"}],"attributes":[{"id":"A31","pred":"hp_id","subj":"T31","obj":"http://purl.obolibrary.org/obo/HP_0003006"}],"text":"SIVmacR71/17E\nTat No info • Morphine (escalating doses of 1–3 mg/kg i.m., q.i.d., 12 months)\n• Morphine in vitro • SIV ↑ Synaptic protein HSPA5\n• Tat ↑ HSPA5 mRNA (in vitro) Rhesus macaques;\nHuman,\nSH-SY5Y neuroblastoma cells in vitro (Pendyala et al. 2015)"}