PMC:7463108 / 1354-1794 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T64264","span":{"begin":195,"end":200},"obj":"Body_part"},{"id":"T26336","span":{"begin":201,"end":206},"obj":"Body_part"},{"id":"T43402","span":{"begin":248,"end":251},"obj":"Body_part"},{"id":"T14505","span":{"begin":334,"end":348},"obj":"Body_part"},{"id":"T96043","span":{"begin":349,"end":357},"obj":"Body_part"},{"id":"T51030","span":{"begin":415,"end":420},"obj":"Body_part"}],"attributes":[{"id":"A9605","pred":"fma_id","subj":"T64264","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A12649","pred":"fma_id","subj":"T26336","obj":"http://purl.org/sig/ont/fma/fma50801"},{"id":"A61751","pred":"fma_id","subj":"T43402","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A77759","pred":"fma_id","subj":"T14505","obj":"http://purl.org/sig/ont/fma/fma67397"},{"id":"A35460","pred":"fma_id","subj":"T96043","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A25030","pred":"fma_id","subj":"T51030","obj":"http://purl.org/sig/ont/fma/fma50801"}],"text":"e comorbidity. Lastly, we present topics that need to be considered in the future to better understand the unique contributions of opioids to the pathophysiology of neuroHIV.\nGraphical Abstract Blood-brain barrier and the neurovascular unit. With HIV and opiate co-exposure (represented below the dotted line), there is breakdown of tight junction proteins and increased leakage of paracellular compounds into the brain. Despite this, opia"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T4","span":{"begin":195,"end":214},"obj":"Body_part"},{"id":"T5","span":{"begin":201,"end":206},"obj":"Body_part"},{"id":"T6","span":{"begin":415,"end":420},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0000120"},{"id":"A5","pred":"uberon_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/UBERON_0000955"}],"text":"e comorbidity. Lastly, we present topics that need to be considered in the future to better understand the unique contributions of opioids to the pathophysiology of neuroHIV.\nGraphical Abstract Blood-brain barrier and the neurovascular unit. With HIV and opiate co-exposure (represented below the dotted line), there is breakdown of tight junction proteins and increased leakage of paracellular compounds into the brain. Despite this, opia"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T47640","span":{"begin":195,"end":200},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T18975","span":{"begin":195,"end":200},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T73965","span":{"begin":201,"end":206},"obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"T21933","span":{"begin":201,"end":206},"obj":"http://www.ebi.ac.uk/efo/EFO_0000302"},{"id":"T54654","span":{"begin":340,"end":348},"obj":"http://purl.obolibrary.org/obo/UBERON_0007651"},{"id":"T9825","span":{"begin":415,"end":420},"obj":"http://purl.obolibrary.org/obo/UBERON_0000955"},{"id":"T35601","span":{"begin":415,"end":420},"obj":"http://www.ebi.ac.uk/efo/EFO_0000302"}],"text":"e comorbidity. Lastly, we present topics that need to be considered in the future to better understand the unique contributions of opioids to the pathophysiology of neuroHIV.\nGraphical Abstract Blood-brain barrier and the neurovascular unit. With HIV and opiate co-exposure (represented below the dotted line), there is breakdown of tight junction proteins and increased leakage of paracellular compounds into the brain. Despite this, opia"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T1","span":{"begin":349,"end":357},"obj":"Chemical"}],"attributes":[{"id":"A1","pred":"chebi_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"e comorbidity. Lastly, we present topics that need to be considered in the future to better understand the unique contributions of opioids to the pathophysiology of neuroHIV.\nGraphical Abstract Blood-brain barrier and the neurovascular unit. With HIV and opiate co-exposure (represented below the dotted line), there is breakdown of tight junction proteins and increased leakage of paracellular compounds into the brain. Despite this, opia"}

{"project":"LitCovid-PubTator","denotations":[{"id":"25","span":{"begin":248,"end":251},"obj":"Species"}],"attributes":[{"id":"A25","pred":"tao:has_database_id","subj":"25","obj":"Tax:12721"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"e comorbidity. Lastly, we present topics that need to be considered in the future to better understand the unique contributions of opioids to the pathophysiology of neuroHIV.\nGraphical Abstract Blood-brain barrier and the neurovascular unit. With HIV and opiate co-exposure (represented below the dotted line), there is breakdown of tight junction proteins and increased leakage of paracellular compounds into the brain. Despite this, opia"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T85650","span":{"begin":321,"end":330},"obj":"http://purl.obolibrary.org/obo/GO_0009056"}],"text":"e comorbidity. Lastly, we present topics that need to be considered in the future to better understand the unique contributions of opioids to the pathophysiology of neuroHIV.\nGraphical Abstract Blood-brain barrier and the neurovascular unit. With HIV and opiate co-exposure (represented below the dotted line), there is breakdown of tight junction proteins and increased leakage of paracellular compounds into the brain. Despite this, opia"}

{"project":"LitCovid-sentences","denotations":[{"id":"T9","span":{"begin":15,"end":174},"obj":"Sentence"},{"id":"T10","span":{"begin":175,"end":242},"obj":"Sentence"},{"id":"T11","span":{"begin":243,"end":421},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"e comorbidity. Lastly, we present topics that need to be considered in the future to better understand the unique contributions of opioids to the pathophysiology of neuroHIV.\nGraphical Abstract Blood-brain barrier and the neurovascular unit. With HIV and opiate co-exposure (represented below the dotted line), there is breakdown of tight junction proteins and increased leakage of paracellular compounds into the brain. Despite this, opia"}