PMC:7463108 / 110421-111201 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T80 114-124 Body_part denotes astrocytes http://purl.org/sig/ont/fma/fma54537
T81 126-135 Body_part denotes microglia http://purl.org/sig/ont/fma/fma68923
T82 137-146 Body_part denotes pericytes http://purl.org/sig/ont/fma/fma63174
T83 274-279 Body_part denotes brain http://purl.org/sig/ont/fma/fma50801
T84 280-284 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T85 362-366 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T86 572-582 Body_part denotes astrocytes http://purl.org/sig/ont/fma/fma54537

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T210 274-279 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T98 108-113 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T99 114-124 http://purl.obolibrary.org/obo/CL_0000127 denotes astrocytes
T100 126-135 http://purl.obolibrary.org/obo/CL_0000129 denotes microglia
T101 274-279 http://purl.obolibrary.org/obo/UBERON_0000955 denotes brain
T102 274-279 http://www.ebi.ac.uk/efo/EFO_0000302 denotes brain
T103 280-290 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T104 362-371 http://purl.obolibrary.org/obo/CL_0000000 denotes cell type
T105 572-582 http://purl.obolibrary.org/obo/CL_0000127 denotes astrocytes
T106 737-738 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T11420 55-67 Chemical denotes dolutegravir http://purl.obolibrary.org/obo/CHEBI_76010
T157 69-78 Chemical denotes tenofovir http://purl.obolibrary.org/obo/CHEBI_134504|http://purl.obolibrary.org/obo/CHEBI_63625|http://purl.obolibrary.org/obo/CHEBI_63716
T41404 83-96 Chemical denotes emtricitabine http://purl.obolibrary.org/obo/CHEBI_31536
T85995 381-390 Chemical denotes tenofovir http://purl.obolibrary.org/obo/CHEBI_134504|http://purl.obolibrary.org/obo/CHEBI_63625|http://purl.obolibrary.org/obo/CHEBI_63716
T97760 467-475 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T53034 597-605 Chemical denotes morphine http://purl.obolibrary.org/obo/CHEBI_17303|http://purl.obolibrary.org/obo/CHEBI_58097
T72635 663-668 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T51837 728-733 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
3684 108-113 Species denotes human Tax:9606
3685 55-67 Chemical denotes dolutegravir MESH:C562325
3686 69-78 Chemical denotes tenofovir MESH:D000068698
3687 83-96 Chemical denotes emtricitabine MESH:D000068679

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1377 0-170 Sentence denotes Another study measured intracellular concentrations of dolutegravir, tenofovir and emtricitabine in primary human astrocytes, microglia, pericytes and BMECs (Patel et al.
T1378 171-177 Sentence denotes 2019).
T1379 178-291 Sentence denotes Intracellular ARV concentrations were typically significantly higher in BMECs than in the other brain cell types.
T1380 292-426 Sentence denotes Dolutegravir achieved the highest relative concentrations within each cell type, whereas tenofovir accumulated the least (Patel et al.
T1381 427-433 Sentence denotes 2019).
T1382 434-583 Sentence denotes Furthermore, 24 h treatment with morphine significantly decreased intracellular accumulation of composite ARV concentrations, but only in astrocytes.
T1383 584-703 Sentence denotes In contrast, morphine exposure significantly increased the net accumulation of drugs within BMECs compared to controls.
T1384 704-773 Sentence denotes BMECs may sequester ARV drugs as a protective mechanism (Patel et al.
T1385 774-780 Sentence denotes 2019).