PMC:7463108 / 102349-102629 JSONTXT

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T30","span":{"begin":42,"end":45},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"In comparison to methadone, buprenorphine has been shown to have fewer pharmacodynamic interactions with ARVs and causes less opioid withdrawal symptoms potentially due to its partial agonism on MOR, but also due to its high affinity and long duration of MOR binding (Walsh et al."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T54595","span":{"begin":17,"end":26},"obj":"Chemical"},{"id":"T51815","span":{"begin":28,"end":41},"obj":"Chemical"}],"attributes":[{"id":"A94635","pred":"chebi_id","subj":"T54595","obj":"http://purl.obolibrary.org/obo/CHEBI_6807"},{"id":"A50009","pred":"chebi_id","subj":"T51815","obj":"http://purl.obolibrary.org/obo/CHEBI_3216"}],"text":"In comparison to methadone, buprenorphine has been shown to have fewer pharmacodynamic interactions with ARVs and causes less opioid withdrawal symptoms potentially due to its partial agonism on MOR, but also due to its high affinity and long duration of MOR binding (Walsh et al."}

{"project":"LitCovid-PubTator","denotations":[{"id":"3508","span":{"begin":195,"end":198},"obj":"Gene"},{"id":"3509","span":{"begin":255,"end":258},"obj":"Gene"},{"id":"3521","span":{"begin":17,"end":26},"obj":"Chemical"},{"id":"3522","span":{"begin":28,"end":41},"obj":"Chemical"},{"id":"3534","span":{"begin":105,"end":109},"obj":"Disease"},{"id":"3535","span":{"begin":126,"end":152},"obj":"Disease"}],"attributes":[{"id":"A3508","pred":"tao:has_database_id","subj":"3508","obj":"Gene:4988"},{"id":"A3509","pred":"tao:has_database_id","subj":"3509","obj":"Gene:4988"},{"id":"A3521","pred":"tao:has_database_id","subj":"3521","obj":"MESH:D008691"},{"id":"A3522","pred":"tao:has_database_id","subj":"3522","obj":"MESH:D002047"},{"id":"A3535","pred":"tao:has_database_id","subj":"3535","obj":"MESH:D013375"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"In comparison to methadone, buprenorphine has been shown to have fewer pharmacodynamic interactions with ARVs and causes less opioid withdrawal symptoms potentially due to its partial agonism on MOR, but also due to its high affinity and long duration of MOR binding (Walsh et al."}

{"project":"LitCovid-sentences","denotations":[{"id":"T1286","span":{"begin":0,"end":280},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"In comparison to methadone, buprenorphine has been shown to have fewer pharmacodynamic interactions with ARVs and causes less opioid withdrawal symptoms potentially due to its partial agonism on MOR, but also due to its high affinity and long duration of MOR binding (Walsh et al."}