PMC:7463108 / 10128-10535 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T92740","span":{"begin":15,"end":21},"obj":"Body_part"},{"id":"T88403","span":{"begin":62,"end":65},"obj":"Body_part"},{"id":"T91823","span":{"begin":275,"end":284},"obj":"Body_part"},{"id":"T67325","span":{"begin":315,"end":324},"obj":"Body_part"},{"id":"T63785","span":{"begin":334,"end":351},"obj":"Body_part"},{"id":"T89876","span":{"begin":353,"end":356},"obj":"Body_part"}],"attributes":[{"id":"A31994","pred":"fma_id","subj":"T92740","obj":"http://purl.org/sig/ont/fma/fma62977"},{"id":"A78119","pred":"fma_id","subj":"T88403","obj":"http://purl.org/sig/ont/fma/fma55675"},{"id":"A13757","pred":"fma_id","subj":"T91823","obj":"http://purl.org/sig/ont/fma/fma54537"},{"id":"A1293","pred":"fma_id","subj":"T67325","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A60748","pred":"fma_id","subj":"T63785","obj":"http://purl.org/sig/ont/fma/fma61889"},{"id":"A59669","pred":"fma_id","subj":"T89876","obj":"http://purl.org/sig/ont/fma/fma61889"}],"text":"ive effects on myelin dysregulation will significantly worsen CNS outcomes.\nPreclinical studies indicate opioid-induced neuroimmune signaling alter the saliency of opioid reward and physical dependence (Narita et al. 2006; Hutchinson et al. 2008, 2009). Direct injections of astrocyte-conditioned medium containing cytokines into the nucleus accumbens (NAc) increase morphine conditioned place preference (N"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T23","span":{"begin":15,"end":21},"obj":"Body_part"},{"id":"T24","span":{"begin":62,"end":65},"obj":"Body_part"},{"id":"T25","span":{"begin":334,"end":351},"obj":"Body_part"},{"id":"T26","span":{"begin":353,"end":356},"obj":"Body_part"}],"attributes":[{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0000345"},{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0001017"},{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0001882"},{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0001882"}],"text":"ive effects on myelin dysregulation will significantly worsen CNS outcomes.\nPreclinical studies indicate opioid-induced neuroimmune signaling alter the saliency of opioid reward and physical dependence (Narita et al. 2006; Hutchinson et al. 2008, 2009). Direct injections of astrocyte-conditioned medium containing cytokines into the nucleus accumbens (NAc) increase morphine conditioned place preference (N"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T8555","span":{"begin":62,"end":65},"obj":"http://www.ebi.ac.uk/efo/EFO_0000302"},{"id":"T18804","span":{"begin":62,"end":65},"obj":"http://www.ebi.ac.uk/efo/EFO_0000908"},{"id":"T44390","span":{"begin":62,"end":65},"obj":"http://purl.obolibrary.org/obo/UBERON_0001017"},{"id":"T44837","span":{"begin":132,"end":141},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T4348","span":{"begin":275,"end":284},"obj":"http://purl.obolibrary.org/obo/CL_0000127"}],"text":"ive effects on myelin dysregulation will significantly worsen CNS outcomes.\nPreclinical studies indicate opioid-induced neuroimmune signaling alter the saliency of opioid reward and physical dependence (Narita et al. 2006; Hutchinson et al. 2008, 2009). Direct injections of astrocyte-conditioned medium containing cytokines into the nucleus accumbens (NAc) increase morphine conditioned place preference (N"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T42","span":{"begin":334,"end":341},"obj":"Chemical"},{"id":"T43","span":{"begin":367,"end":375},"obj":"Chemical"}],"attributes":[{"id":"A42","pred":"chebi_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/CHEBI_33252"},{"id":"A43","pred":"chebi_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_17303"},{"id":"A44","pred":"chebi_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/CHEBI_58097"}],"text":"ive effects on myelin dysregulation will significantly worsen CNS outcomes.\nPreclinical studies indicate opioid-induced neuroimmune signaling alter the saliency of opioid reward and physical dependence (Narita et al. 2006; Hutchinson et al. 2008, 2009). Direct injections of astrocyte-conditioned medium containing cytokines into the nucleus accumbens (NAc) increase morphine conditioned place preference (N"}

{"project":"LitCovid-PubTator","denotations":[{"id":"182","span":{"begin":367,"end":375},"obj":"Chemical"}],"attributes":[{"id":"A182","pred":"tao:has_database_id","subj":"182","obj":"MESH:D009020"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"ive effects on myelin dysregulation will significantly worsen CNS outcomes.\nPreclinical studies indicate opioid-induced neuroimmune signaling alter the saliency of opioid reward and physical dependence (Narita et al. 2006; Hutchinson et al. 2008, 2009). Direct injections of astrocyte-conditioned medium containing cytokines into the nucleus accumbens (NAc) increase morphine conditioned place preference (N"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T25593","span":{"begin":132,"end":141},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T77592","span":{"begin":376,"end":404},"obj":"http://purl.obolibrary.org/obo/GO_1990708"}],"text":"ive effects on myelin dysregulation will significantly worsen CNS outcomes.\nPreclinical studies indicate opioid-induced neuroimmune signaling alter the saliency of opioid reward and physical dependence (Narita et al. 2006; Hutchinson et al. 2008, 2009). Direct injections of astrocyte-conditioned medium containing cytokines into the nucleus accumbens (NAc) increase morphine conditioned place preference (N"}

{"project":"LitCovid-sentences","denotations":[{"id":"T106","span":{"begin":76,"end":216},"obj":"Sentence"},{"id":"T107","span":{"begin":217,"end":240},"obj":"Sentence"},{"id":"T108","span":{"begin":241,"end":253},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"ive effects on myelin dysregulation will significantly worsen CNS outcomes.\nPreclinical studies indicate opioid-induced neuroimmune signaling alter the saliency of opioid reward and physical dependence (Narita et al. 2006; Hutchinson et al. 2008, 2009). Direct injections of astrocyte-conditioned medium containing cytokines into the nucleus accumbens (NAc) increase morphine conditioned place preference (N"}

{"project":"2_test","denotations":[{"id":"32876803-16407899-62957885","span":{"begin":217,"end":221},"obj":"16407899"},{"id":"32876803-18706994-62957886","span":{"begin":241,"end":245},"obj":"18706994"},{"id":"32876803-18938237-62957887","span":{"begin":247,"end":251},"obj":"18938237"}],"text":"ive effects on myelin dysregulation will significantly worsen CNS outcomes.\nPreclinical studies indicate opioid-induced neuroimmune signaling alter the saliency of opioid reward and physical dependence (Narita et al. 2006; Hutchinson et al. 2008, 2009). Direct injections of astrocyte-conditioned medium containing cytokines into the nucleus accumbens (NAc) increase morphine conditioned place preference (N"}