PMC:7461420 / 87345-87864 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T413","span":{"begin":402,"end":406},"obj":"Disease"}],"attributes":[{"id":"A413","pred":"mondo_id","subj":"T413","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Drug repurposing is an attractive strategy for finding new indications for already well‐established, marketed drugs or highly characterized compounds. It is a fast way to identify of new therapeutic options directly available for clinical use or eligible for accelerated approval for various diseases and disorders. An extensive effort has been made in repurposing approved drugs since the outbreak of SARS‐CoV‐1. Below, we summarize selected drug repositioning strategies for anticoronaviral therapy and their results."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T1004","span":{"begin":157,"end":158},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T1005","span":{"begin":336,"end":339},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"}],"text":"Drug repurposing is an attractive strategy for finding new indications for already well‐established, marketed drugs or highly characterized compounds. It is a fast way to identify of new therapeutic options directly available for clinical use or eligible for accelerated approval for various diseases and disorders. An extensive effort has been made in repurposing approved drugs since the outbreak of SARS‐CoV‐1. Below, we summarize selected drug repositioning strategies for anticoronaviral therapy and their results."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T10086","span":{"begin":110,"end":115},"obj":"Chemical"},{"id":"T554","span":{"begin":374,"end":379},"obj":"Chemical"},{"id":"T48660","span":{"begin":443,"end":447},"obj":"Chemical"}],"attributes":[{"id":"A59185","pred":"chebi_id","subj":"T10086","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A50289","pred":"chebi_id","subj":"T554","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"},{"id":"A8793","pred":"chebi_id","subj":"T48660","obj":"http://purl.obolibrary.org/obo/CHEBI_23888"}],"text":"Drug repurposing is an attractive strategy for finding new indications for already well‐established, marketed drugs or highly characterized compounds. It is a fast way to identify of new therapeutic options directly available for clinical use or eligible for accelerated approval for various diseases and disorders. An extensive effort has been made in repurposing approved drugs since the outbreak of SARS‐CoV‐1. Below, we summarize selected drug repositioning strategies for anticoronaviral therapy and their results."}

{"project":"LitCovid-PubTator","denotations":[{"id":"2699","span":{"begin":402,"end":410},"obj":"Species"}],"attributes":[{"id":"A2699","pred":"tao:has_database_id","subj":"2699","obj":"Tax:694009"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Drug repurposing is an attractive strategy for finding new indications for already well‐established, marketed drugs or highly characterized compounds. It is a fast way to identify of new therapeutic options directly available for clinical use or eligible for accelerated approval for various diseases and disorders. An extensive effort has been made in repurposing approved drugs since the outbreak of SARS‐CoV‐1. Below, we summarize selected drug repositioning strategies for anticoronaviral therapy and their results."}

{"project":"LitCovid-sentences","denotations":[{"id":"T758","span":{"begin":0,"end":150},"obj":"Sentence"},{"id":"T759","span":{"begin":151,"end":315},"obj":"Sentence"},{"id":"T760","span":{"begin":316,"end":413},"obj":"Sentence"},{"id":"T761","span":{"begin":414,"end":519},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Drug repurposing is an attractive strategy for finding new indications for already well‐established, marketed drugs or highly characterized compounds. It is a fast way to identify of new therapeutic options directly available for clinical use or eligible for accelerated approval for various diseases and disorders. An extensive effort has been made in repurposing approved drugs since the outbreak of SARS‐CoV‐1. Below, we summarize selected drug repositioning strategies for anticoronaviral therapy and their results."}