PMC:7461420 / 7667-8015 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T33","span":{"begin":15,"end":22},"obj":"Body_part"},{"id":"T34","span":{"begin":207,"end":213},"obj":"Body_part"},{"id":"T35","span":{"begin":232,"end":238},"obj":"Body_part"},{"id":"T36","span":{"begin":329,"end":344},"obj":"Body_part"}],"attributes":[{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma82764"},{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma63841"}],"text":"When the spike protein attaches to its host cellular receptor, it is cleaved into two parts (S1 and S2) by extracellular proteases. While S1 remains attached to its target, S2 is further cleaved by the host cell's own transmembrane serine protease 2 (TMPRSS2). This process induces the fusion of the viral membrane with the host cell's membrane. 15"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T80","span":{"begin":93,"end":95},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T81","span":{"begin":100,"end":102},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T82","span":{"begin":100,"end":102},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"},{"id":"T83","span":{"begin":138,"end":140},"obj":"http://purl.obolibrary.org/obo/CLO_0050050"},{"id":"T84","span":{"begin":173,"end":175},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T85","span":{"begin":173,"end":175},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"},{"id":"T86","span":{"begin":207,"end":213},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T87","span":{"begin":306,"end":314},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T88","span":{"begin":329,"end":335},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T89","span":{"begin":336,"end":344},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"}],"text":"When the spike protein attaches to its host cellular receptor, it is cleaved into two parts (S1 and S2) by extracellular proteases. While S1 remains attached to its target, S2 is further cleaved by the host cell's own transmembrane serine protease 2 (TMPRSS2). This process induces the fusion of the viral membrane with the host cell's membrane. 15"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T33","span":{"begin":15,"end":22},"obj":"Chemical"},{"id":"T34","span":{"begin":100,"end":102},"obj":"Chemical"},{"id":"T35","span":{"begin":173,"end":175},"obj":"Chemical"},{"id":"T36","span":{"begin":232,"end":238},"obj":"Chemical"}],"attributes":[{"id":"A33","pred":"chebi_id","subj":"T33","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A34","pred":"chebi_id","subj":"T34","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A35","pred":"chebi_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A36","pred":"chebi_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/CHEBI_17822"}],"text":"When the spike protein attaches to its host cellular receptor, it is cleaved into two parts (S1 and S2) by extracellular proteases. While S1 remains attached to its target, S2 is further cleaved by the host cell's own transmembrane serine protease 2 (TMPRSS2). This process induces the fusion of the viral membrane with the host cell's membrane. 15"}

{"project":"LitCovid-PubTator","denotations":[{"id":"307","span":{"begin":9,"end":14},"obj":"Gene"},{"id":"308","span":{"begin":218,"end":249},"obj":"Gene"},{"id":"309","span":{"begin":251,"end":258},"obj":"Gene"}],"attributes":[{"id":"A307","pred":"tao:has_database_id","subj":"307","obj":"Gene:43740568"},{"id":"A308","pred":"tao:has_database_id","subj":"308","obj":"Gene:7113"},{"id":"A309","pred":"tao:has_database_id","subj":"309","obj":"Gene:7113"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"When the spike protein attaches to its host cellular receptor, it is cleaved into two parts (S1 and S2) by extracellular proteases. While S1 remains attached to its target, S2 is further cleaved by the host cell's own transmembrane serine protease 2 (TMPRSS2). This process induces the fusion of the viral membrane with the host cell's membrane. 15"}

{"project":"LitCovid-sentences","denotations":[{"id":"T94","span":{"begin":0,"end":131},"obj":"Sentence"},{"id":"T95","span":{"begin":132,"end":260},"obj":"Sentence"},{"id":"T96","span":{"begin":261,"end":345},"obj":"Sentence"},{"id":"T97","span":{"begin":346,"end":348},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"When the spike protein attaches to its host cellular receptor, it is cleaved into two parts (S1 and S2) by extracellular proteases. While S1 remains attached to its target, S2 is further cleaved by the host cell's own transmembrane serine protease 2 (TMPRSS2). This process induces the fusion of the viral membrane with the host cell's membrane. 15"}