PMC:7461420 / 69135-69422
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T325 | 0-3 | Disease | denotes | HTS | http://purl.obolibrary.org/obo/MONDO_0011549 |
| T326 | 124-128 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T837 | 33-36 | http://purl.obolibrary.org/obo/CLO_0001230 | denotes | 293 |
| T838 | 33-36 | http://purl.obolibrary.org/obo/CLO_0037237 | denotes | 293 |
| T839 | 33-36 | http://purl.obolibrary.org/obo/CLO_0050903 | denotes | 293 |
| T840 | 33-36 | http://purl.obolibrary.org/obo/CLO_0054249 | denotes | 293 |
| T841 | 33-36 | http://purl.obolibrary.org/obo/CLO_0054250 | denotes | 293 |
| T842 | 33-36 | http://purl.obolibrary.org/obo/CLO_0054251 | denotes | 293 |
| T843 | 33-36 | http://purl.obolibrary.org/obo/CLO_0054252 | denotes | 293 |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T42754 | 65-74 | Chemical | denotes | dipeptide | http://purl.obolibrary.org/obo/CHEBI_46761 |
| T30698 | 251-261 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 2152 | 135-139 | Gene | denotes | Mpro | Gene:8673700 |
| 2153 | 124-132 | Species | denotes | SARS‐CoV | Tax:694009 |
| 2154 | 194-197 | Species | denotes | SAR | Tax:2698737 |
| 2155 | 65-74 | Chemical | denotes | dipeptide | MESH:D004151 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T600 | 0-181 | Sentence | denotes | HTS of NIH molecular libraries (~293 000 substances) yielded the dipeptide 122 containing 3‐pyridyl as hit compound against SARS‐CoV‐1 Mpro with an IC50 value of 2.2 µM (Figure 30). |
| T601 | 182-276 | Sentence | denotes | Preliminary SAR studies identified 123 and 124 as the most promising inhibitors of the series. |
| T602 | 277-287 | Sentence | denotes | 184 , 185 |