PMC:7461420 / 56272-56567
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T249 | 251-259 | Body_part | denotes | cysteine | http://purl.org/sig/ont/fma/fma82751 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T713 | 99-100 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T714 | 159-160 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T52365 | 71-80 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T9616 | 132-137 | Chemical | denotes | amide | http://purl.obolibrary.org/obo/CHEBI_29337|http://purl.obolibrary.org/obo/CHEBI_32988 |
T14214 | 138-144 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
T69815 | 188-194 | Chemical | denotes | amides | http://purl.obolibrary.org/obo/CHEBI_32988 |
T98 | 251-259 | Chemical | denotes | cysteine | http://purl.obolibrary.org/obo/CHEBI_15356 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
1703 | 251-268 | Gene | denotes | cysteine protease | Gene:1508 |
1704 | 4-13 | Chemical | denotes | thioketal | |
1705 | 50-56 | Chemical | denotes | Cys145 | |
1706 | 113-118 | Chemical | denotes | His41 | |
1707 | 132-137 | Chemical | denotes | amide | MESH:D000577 |
1708 | 138-144 | Chemical | denotes | oxygen | MESH:D010100 |
1709 | 188-194 | Chemical | denotes | amides | MESH:D000577 |
1710 | 198-204 | Chemical | denotes | Gly143 | |
1711 | 206-212 | Chemical | denotes | Cys145 | |
1712 | 227-233 | Chemical | denotes | Ser144 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T492 | 0-295 | Sentence | denotes | The thioketal that resulted from the nucleophilic Cys145 attacking the inhibitor, is stabilized by a H‐bond from His41, whereas the amide oxygen of 67 accepts a H‐bond from the main‐chain amides of Gly143, Cys145, and in part, Ser144 that make up the cysteine protease's canonical oxyanion hole. |