PMC:7461420 / 49102-49700
Annnotations
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T626 | 119-121 | http://purl.obolibrary.org/obo/CLO_0008922 | denotes | S2 |
| T627 | 119-121 | http://purl.obolibrary.org/obo/CLO_0050052 | denotes | S2 |
| T628 | 146-148 | http://purl.obolibrary.org/obo/CLO_0008307 | denotes | P2 |
| T629 | 362-364 | http://purl.obolibrary.org/obo/CLO_0008285 | denotes | P1 |
| T630 | 423-429 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T565 | 35-40 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T566 | 119-121 | Chemical | denotes | S2 | http://purl.obolibrary.org/obo/CHEBI_29387 |
| T567 | 146-148 | Chemical | denotes | P2 | http://purl.obolibrary.org/obo/CHEBI_33472 |
| T568 | 272-280 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
| T569 | 362-364 | Chemical | denotes | P1 | http://purl.obolibrary.org/obo/CHEBI_60949 |
| T570 | 365-374 | Chemical | denotes | imidazole | http://purl.obolibrary.org/obo/CHEBI_14434|http://purl.obolibrary.org/obo/CHEBI_16069 |
| T572 | 390-398 | Chemical | denotes | aldehyde | http://purl.obolibrary.org/obo/CHEBI_17478 |
| T573 | 410-415 | Chemical | denotes | group | http://purl.obolibrary.org/obo/CHEBI_24433 |
| T574 | 456-461 | Chemical | denotes | butyl | http://purl.obolibrary.org/obo/CHEBI_41264 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1472 | 65-85 | Chemical | denotes | octahydroisochromene | |
| 1473 | 286-314 | Chemical | denotes | (1S,3S)‐octahydroisochromene | |
| 1474 | 362-374 | Chemical | denotes | P1‐imidazole | |
| 1475 | 390-398 | Chemical | denotes | aldehyde | MESH:D000447 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T440 | 0-156 | Sentence | denotes | Rather recently, the same research group explored the ability of octahydroisochromene to interact with the hydrophobic S2 pocket as an innovative P2‐moiety. |
| T441 | 157-249 | Sentence | denotes | 150 To identify the best specific configuration, all possible diastereomers were evaluated. |
| T442 | 250-435 | Sentence | denotes | It was found that the molecule with (1S,3S)‐octahydroisochromene 53–56 could secure the optimal position of the P1‐imidazole as well as the aldehyde functional group at the active site. |
| T443 | 436-598 | Sentence | denotes | Additionally, the N‐butyl side chain attached to the 1‐position of the fused ring system was recognized to be important for establishing hydrophobic interactions. |