PMC:7461420 / 42553-43027
Annnotations
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T219 | 89-93 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
| T220 | 402-412 | Disease | denotes | infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
| T221 | 413-423 | Disease | denotes | bronchitis | http://purl.obolibrary.org/obo/MONDO_0003781 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T519 | 8-16 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptidic |
| T520 | 27-28 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T521 | 158-159 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
| T522 | 337-340 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T523 | 371-379 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
| T524 | 386-392 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
| T525 | 424-429 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T444 | 17-21 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
| T445 | 37-45 | Chemical | denotes | acceptor | http://purl.obolibrary.org/obo/CHEBI_15339 |
| T446 | 175-184 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
| T447 | 361-370 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T17 | 413-423 | Phenotype | denotes | bronchitis | http://purl.obolibrary.org/obo/HP_0012387 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1277 | 302-306 | Gene | denotes | Mpro | Gene:8673700 |
| 1278 | 240-244 | Gene | denotes | Mpro | Gene:8673700 |
| 1279 | 89-97 | Species | denotes | SARS‐CoV | Tax:694009 |
| 1280 | 217-221 | Species | denotes | CoVs | Tax:11118 |
| 1281 | 231-239 | Species | denotes | MERS‐CoV | Tax:1335626 |
| 1282 | 266-275 | Species | denotes | HCoV‐229E | Tax:11137 |
| 1283 | 277-286 | Species | denotes | HCoV‐NL63 | Tax:277944 |
| 1284 | 292-301 | Species | denotes | HCoV‐HKU1 | Tax:290028 |
| 1285 | 402-429 | Species | denotes | infectious bronchitis virus | Tax:11120 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T389 | 0-135 | Sentence | denotes | Another peptidic drug with a Michael acceptor was N3 (40), which was reported to inhibit SARS‐CoV‐1 3CLpro (K i, 9.0 µM) by Yang et al. |
| T390 | 136-307 | Sentence | denotes | It was observed to be a broad‐spectrum antiviral compound, also inhibiting other CoVs, such as MERS‐CoV Mpro (IC50, 0.28µM), 135 HCoV‐229E, HCoV‐NL63, and HCoV‐HKU1 Mpro. |
| T391 | 308-430 | Sentence | denotes | 135 , 136 , 137 , 138 It has also exhibited high antiviral activity in an animal model of infectious bronchitis virus. |
| T392 | 431-474 | Sentence | denotes | 137 The CC50 of 40 is greater than 133 μM. |