PMC:7461420 / 34065-34388 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T186","span":{"begin":47,"end":52},"obj":"Body_part"}],"attributes":[{"id":"A186","pred":"fma_id","subj":"T186","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"f 5.33 µM. In a pseudotype‐based assay in 293T cells, the EC50 value of 23 was around 6.4 µM, and no cytotoxicity was detected below 100 µM. 48\nPhenotypic screening approaches led to the identification of several viral entry inhibitors. This approach has the advantage of finding cellular‐active compounds, providing inform"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T401","span":{"begin":14,"end":15},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T402","span":{"begin":42,"end":46},"obj":"http://purl.obolibrary.org/obo/CLO_0050894"},{"id":"T403","span":{"begin":42,"end":46},"obj":"http://purl.obolibrary.org/obo/CLO_0051650"},{"id":"T404","span":{"begin":42,"end":46},"obj":"http://purl.obolibrary.org/obo/CLO_0052052"},{"id":"T405","span":{"begin":47,"end":52},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T406","span":{"begin":141,"end":143},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"},{"id":"T407","span":{"begin":251,"end":254},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T408","span":{"begin":289,"end":295},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"f 5.33 µM. In a pseudotype‐based assay in 293T cells, the EC50 value of 23 was around 6.4 µM, and no cytotoxicity was detected below 100 µM. 48\nPhenotypic screening approaches led to the identification of several viral entry inhibitors. This approach has the advantage of finding cellular‐active compounds, providing inform"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T305","span":{"begin":225,"end":235},"obj":"Chemical"}],"attributes":[{"id":"A305","pred":"chebi_id","subj":"T305","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"}],"text":"f 5.33 µM. In a pseudotype‐based assay in 293T cells, the EC50 value of 23 was around 6.4 µM, and no cytotoxicity was detected below 100 µM. 48\nPhenotypic screening approaches led to the identification of several viral entry inhibitors. This approach has the advantage of finding cellular‐active compounds, providing inform"}

{"project":"LitCovid-PubTator","denotations":[{"id":"1078","span":{"begin":101,"end":113},"obj":"Disease"},{"id":"1079","span":{"begin":42,"end":46},"obj":"CellLine"}],"attributes":[{"id":"A1078","pred":"tao:has_database_id","subj":"1078","obj":"MESH:D064420"},{"id":"A1079","pred":"tao:has_database_id","subj":"1079","obj":"CVCL:0063"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"f 5.33 µM. In a pseudotype‐based assay in 293T cells, the EC50 value of 23 was around 6.4 µM, and no cytotoxicity was detected below 100 µM. 48\nPhenotypic screening approaches led to the identification of several viral entry inhibitors. This approach has the advantage of finding cellular‐active compounds, providing inform"}

{"project":"LitCovid-sentences","denotations":[{"id":"T315","span":{"begin":11,"end":140},"obj":"Sentence"},{"id":"T316","span":{"begin":141,"end":143},"obj":"Sentence"},{"id":"T317","span":{"begin":144,"end":236},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"f 5.33 µM. In a pseudotype‐based assay in 293T cells, the EC50 value of 23 was around 6.4 µM, and no cytotoxicity was detected below 100 µM. 48\nPhenotypic screening approaches led to the identification of several viral entry inhibitors. This approach has the advantage of finding cellular‐active compounds, providing inform"}