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PMC:7461420 / 29529-30172 JSONTXT

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LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T157 83-92 Body_part denotes endosomal http://purl.org/sig/ont/fma/fma67180
T158 209-216 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T159 262-269 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T160 521-526 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T161 540-546 Body_part denotes serine http://purl.org/sig/ont/fma/fma82764

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T167 410-420 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T168 494-498 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T325 0-8 http://purl.obolibrary.org/obo/UBERON_0000158 denotes Membrane
T326 169-175 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T327 224-226 http://purl.obolibrary.org/obo/CLO_0050050 denotes S1
T328 227-229 http://purl.obolibrary.org/obo/CLO_0008922 denotes S2
T329 227-229 http://purl.obolibrary.org/obo/CLO_0050052 denotes S2
T330 247-255 http://purl.obolibrary.org/obo/CLO_0001658 denotes activate
T331 274-282 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T332 422-423 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T333 514-526 http://purl.obolibrary.org/obo/CLO_0051719 denotes VeroE6 cells
T334 538-539 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T335 561-570 http://purl.obolibrary.org/obo/CLO_0001658 denotes activates
T336 617-625 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T337 640-643 http://purl.obolibrary.org/obo/CLO_0054060 denotes 102

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T259 209-216 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T260 227-229 Chemical denotes S2 http://purl.obolibrary.org/obo/CHEBI_29387
T261 262-269 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T262 540-546 Chemical denotes serine http://purl.obolibrary.org/obo/CHEBI_17822

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T37 0-15 http://purl.obolibrary.org/obo/GO_0061025 denotes Membrane fusion
T38 274-289 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion
T39 474-490 http://purl.obolibrary.org/obo/GO_0019058 denotes viral life cycle
T40 617-632 http://purl.obolibrary.org/obo/GO_0061025 denotes membrane fusion

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
938 132-143 Gene denotes cathepsin L Gene:1514
939 145-152 Gene denotes TMPRSS2 Gene:7113
940 458-465 Gene denotes TMPRSS2 Gene:7113
941 531-536 Gene denotes Furin Gene:103231185
942 49-52 Species denotes CoV Tax:11118
943 571-579 Species denotes MERS‐CoV Tax:1335626
944 540-546 Chemical denotes serine MESH:D012694
945 406-420 Disease denotes CoV infections MESH:D018352
946 494-513 Disease denotes SARS‐CoV‐2‐infected MESH:C000657245
947 514-520 CellLine denotes VeroE6 CVCL:0574

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T278 0-290 Sentence denotes Membrane fusion is also the crucial step for the CoV life cycle in the nonclathrin/endosomal route, in which host proteases such as cathepsin L, TMPRSS2, and TMPRSS11D (airway trypsin‐like protease) cut the S protein at the S1/S2 cleavage site to activate the S protein for membrane fusion.
T279 291-421 Sentence denotes 101 Interference with this process by targeting these proteases could become an attractive strategy for combating CoV infections.
T280 422-527 Sentence denotes A recent study confirms the role of TMPRSS2 for the viral life cycle in SARS‐CoV‐2‐infected VeroE6 cells.
T281 528-639 Sentence denotes 5 Furin (a serine endoprotease) activates MERS‐CoV to initiate the nonclathrin mediated membrane fusion event.
T282 640-643 Sentence denotes 102