PMC:7461420 / 22914-23172 JSONTXT

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T131","span":{"begin":49,"end":53},"obj":"Disease"},{"id":"T132","span":{"begin":60,"end":69},"obj":"Disease"},{"id":"T133","span":{"begin":140,"end":144},"obj":"Disease"},{"id":"T134","span":{"begin":245,"end":249},"obj":"Disease"}],"attributes":[{"id":"A131","pred":"mondo_id","subj":"T131","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A132","pred":"mondo_id","subj":"T132","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A133","pred":"mondo_id","subj":"T133","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A134","pred":"mondo_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"67 , 68 Mechanistic studies of chloroquine for SARS‐CoV‐1 infection revealed that it could also weaken the interaction between the RBD of SARS‐CoV‐1 and ACE2 by interfering with terminal glycosylation of ACE2, thereby reducing its affinity to SARS‐CoV‐1 S."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T211","span":{"begin":33,"end":44},"obj":"Chemical"}],"attributes":[{"id":"A211","pred":"chebi_id","subj":"T211","obj":"http://purl.obolibrary.org/obo/CHEBI_3638"}],"text":"67 , 68 Mechanistic studies of chloroquine for SARS‐CoV‐1 infection revealed that it could also weaken the interaction between the RBD of SARS‐CoV‐1 and ACE2 by interfering with terminal glycosylation of ACE2, thereby reducing its affinity to SARS‐CoV‐1 S."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T23","span":{"begin":180,"end":202},"obj":"http://purl.obolibrary.org/obo/GO_0033578"},{"id":"T24","span":{"begin":189,"end":202},"obj":"http://purl.obolibrary.org/obo/GO_0070085"}],"text":"67 , 68 Mechanistic studies of chloroquine for SARS‐CoV‐1 infection revealed that it could also weaken the interaction between the RBD of SARS‐CoV‐1 and ACE2 by interfering with terminal glycosylation of ACE2, thereby reducing its affinity to SARS‐CoV‐1 S."}

{"project":"LitCovid-PubTator","denotations":[{"id":"735","span":{"begin":155,"end":159},"obj":"Gene"},{"id":"736","span":{"begin":206,"end":210},"obj":"Gene"},{"id":"742","span":{"begin":140,"end":148},"obj":"Species"},{"id":"743","span":{"begin":245,"end":253},"obj":"Species"},{"id":"746","span":{"begin":33,"end":44},"obj":"Chemical"},{"id":"747","span":{"begin":49,"end":69},"obj":"Disease"}],"attributes":[{"id":"A735","pred":"tao:has_database_id","subj":"735","obj":"Gene:59272"},{"id":"A736","pred":"tao:has_database_id","subj":"736","obj":"Gene:59272"},{"id":"A742","pred":"tao:has_database_id","subj":"742","obj":"Tax:694009"},{"id":"A743","pred":"tao:has_database_id","subj":"743","obj":"Tax:694009"},{"id":"A746","pred":"tao:has_database_id","subj":"746","obj":"MESH:D002738"},{"id":"A747","pred":"tao:has_database_id","subj":"747","obj":"MESH:C000657245"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"67 , 68 Mechanistic studies of chloroquine for SARS‐CoV‐1 infection revealed that it could also weaken the interaction between the RBD of SARS‐CoV‐1 and ACE2 by interfering with terminal glycosylation of ACE2, thereby reducing its affinity to SARS‐CoV‐1 S."}

{"project":"LitCovid-sentences","denotations":[{"id":"T223","span":{"begin":0,"end":258},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"67 , 68 Mechanistic studies of chloroquine for SARS‐CoV‐1 infection revealed that it could also weaken the interaction between the RBD of SARS‐CoV‐1 and ACE2 by interfering with terminal glycosylation of ACE2, thereby reducing its affinity to SARS‐CoV‐1 S."}