PMC:7461420 / 19353-20038
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T109 | 254-259 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T110 | 303-314 | Body_part | denotes | endothelium | http://purl.org/sig/ont/fma/fma63916 |
T111 | 327-331 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T112 | 356-381 | Body_part | denotes | alveolar epithelial cells | http://purl.org/sig/ont/fma/fma62499 |
T113 | 376-381 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T114 | 426-433 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T115 | 465-475 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
T116 | 528-535 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T117 | 554-561 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T118 | 680-684 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T6 | 303-314 | Body_part | denotes | endothelium | http://purl.obolibrary.org/obo/UBERON_0001986 |
T7 | 327-331 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T8 | 680-684 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T105 | 20-24 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T106 | 67-71 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T107 | 96-100 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T108 | 189-198 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T109 | 200-204 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T110 | 387-391 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T111 | 439-443 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T112 | 515-519 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T113 | 541-545 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T218 | 152-159 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T219 | 235-236 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T220 | 254-259 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T221 | 267-270 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T222 | 303-314 | http://purl.obolibrary.org/obo/UBERON_0001986 | denotes | endothelium |
T223 | 327-331 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T224 | 327-331 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T225 | 365-375 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T226 | 376-381 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T227 | 405-415 | http://purl.obolibrary.org/obo/CLO_0009900 | denotes | 76% of its |
T228 | 459-460 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T229 | 603-605 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
T230 | 680-684 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T231 | 680-684 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T148 | 426-433 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T149 | 465-475 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
T150 | 465-470 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T151 | 471-475 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T152 | 528-535 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T153 | 554-561 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T18 | 647-656 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | virulence |
T19 | 647-656 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | virulence |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
617 | 227-231 | Gene | denotes | ACE2 | Gene:59272 |
618 | 416-421 | Gene | denotes | spike | Gene:43740568 |
619 | 423-424 | Gene | denotes | S | Gene:43740568 |
620 | 571-575 | Gene | denotes | ACE2 | Gene:59272 |
621 | 552-553 | Gene | denotes | S | Gene:43740568 |
622 | 20-30 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
623 | 67-75 | Species | denotes | SARS‐CoV | Tax:694009 |
624 | 200-208 | Species | denotes | SARS‐CoV | Tax:694009 |
625 | 387-397 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
626 | 439-447 | Species | denotes | SARS‐CoV | Tax:694009 |
627 | 515-523 | Species | denotes | SARS‐CoV | Tax:694009 |
628 | 541-551 | Species | denotes | SARS‐CoV‐2 | Tax:2697049 |
629 | 189-198 | Disease | denotes | infection | MESH:D007239 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T193 | 0-118 | Sentence | denotes | The genetic code of SARS‐CoV‐2 shares noticeable similarities with SARS‐CoV‐1, which caused the SARS epidemic in 2002. |
T194 | 119-199 | Sentence | denotes | 26 , 54 More importantly, both viruses have identical mechanisms of infection. |
T195 | 200-382 | Sentence | denotes | SARS‐CoV‐1 uses the host's ACE2 as a portal to infect cells, which has high expression in the vascular endothelium 55 and the lung, particularly in type 2 alveolar epithelial cells. |
T196 | 383-450 | Sentence | denotes | 56 SARS‐CoV‐2 shares 76% of its spike (S) protein with SARS‐CoV‐1. |
T197 | 451-685 | Sentence | denotes | Despite a few amino acid differences in its RBD compared to the SARS‐CoV‐1 S protein, the SARS‐CoV‐2 S protein binds to ACE2 with even greater affinity 27 offering an explanation for its greater virulence and preference for the lung. |